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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
P19 EC
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "P19 EC" in MCE Product Catalog:
9
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Tranylcypromine hydrochloride (SKF 385 hydrochloride) is an irreversible inhibitor of lysine-specific demethylase 1 (LSD1/BHC110) and monoamine oxidase (MAO). Tranylcypromine hydrochloride inhibits LSD1, MAO A and MAO B with IC50s of 20.7, 2.3 and 0.95 μM, respectively. Tranylcypromine hydrochloride can be used for the research of depression .
Cat. No.: HY-P99248
CAS No.: 1612838-76-2
Synonyms: Risankizumab rzaa; BI 655066; ABBV-066
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Cat. No.: HY-P9931
CAS No.: 1350289-85-8
Synonyms: CNTO 1959
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Cat. No.: HY-P99737
CAS No.: 1884201-71-1
Synonyms: LY3074828
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Cat. No.: HY-P990217
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Cat. No.: HY-P99256
CAS No.: 1326244-10-3
Synonyms: SCH 900222; MK 3222; Anti-Human IL23 RECombinant Antibody
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Cat. No.: HY-P99485
CAS No.: 1610353-18-8
Synonyms: AMG 139; MEDI2070
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Cat. No.: HY-P990057
CAS No.: 2622900-74-5
Synonyms: IBI-112
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Cat. No.: HY-P1494
CAS No.: 57468-17-4
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Shz-1, a small cardiogenic molecule, induces various cardiac-specific genes including sarcomeric tropomyosin in P19CL6 cells. Shz-1 induces Nkx2.5 expression in mouse. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells .
Cat. No.: HY-P991277
Synonyms: HS-20137
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Cat. No.: HY-P991274
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Cat. No.: HY-P11198
Cat. No.: HY-P991408
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Cat. No.: HY-180977
CAS No.: 2512843-74-0
P19P is a BCR-ABL PROTAC degrader based on Ponatinib (HY-12047), with a DC50 value of approximately 20 nM for the wild-type BCR-ABL protein. P19P can effectively degrade various drug-resistant mutants such as T315I, E255K, H396R, and V468F, and exhibits potent anti-proliferative activity in BaF3-BCR-ABL (T315I) cells. P19P maintains strong inhibitory activity against ABL (T315I), with a IC50 of 13.1 nM. P19P does not inhibit the formation of vascular lumens in HUVEC. P19P can be used for research on chronic myeloid leukemia and acute lymphoblastic leukemia .
Cat. No.: HY-180981
CAS No.: 2635386-55-7
P19As is a BCR-ABL PROTAC degrader based on Asciminib (HY-104010), with a DC50 value of approximately 200 nM for the wild-type BCR-ABL protein. P19As can degrade the T315I mutant and exhibits potent anti-proliferative activity in BaF3-BCR-ABL (T315I) cells. P19As can be used for the study of chronic myeloid leukemia and acute lymphoblastic leukemia .
Cat. No.: HY-180978
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H2N-PEG3-C2-Trizole-C3-COOH is a is a PEG-based PROTAC linker that can be used for the synthesis of PROTACs, such as P19As (HY-180981) and P19P (HY-180977) .
Cat. No.: HY-180982
CAS No.: 3106065-83-9
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Asciminib-NH2 is a BCR-ABL ligand and can be used for the synthesis of PROTACs, such as P19As (HY-180981) .
Cat. No.: HY-108440R
CAS No.: 326886-05-9
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Shz-1 (Standard) is the analytical standard of Shz-1 (HY-108440). This product is intended for research and analytical applications. Shz-1, a small cardiogenic molecule, induces various cardiac-specific genes including sarcomeric tropomyosin in P19CL6 cells. Shz-1 induces Nkx2.5 expression in mouse. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
