34 Results for "

PET imaging agent

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "PET imaging agent" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-128890
CAS No.: 170908-81-3
Purity:  ≥95.0%
Target:  

ADC Linkers

Research Areas:  

Cancer

DOTA-NHS-ester is a linker for affibody molecules and is applied in small animals PET, SPECT, and CT. DOTA-NHS-ester can be used to label radiotherapeutic agents or imaging probes for the detection of tumors .
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1
1 Cited Publications
Cat. No.: HY-W087028
CAS No.: 1338231-09-6
NOTA-NHS ester is a chelating agent. NOTA-NHS ester can be coupled with T140 (HY-P4810) to produce NOTA-T140. NOTA-T140 can be radiolabeled with Al[ 18F]. The uptake of Al[ 18F]NOTA-T140 in tumors is correlated with the expression level of CXCR4. Al[ 18F]NOTA-T140 can be used in tumor PET imaging studies. NOTA-NHS ester can be used for fluorescent labeling .
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1
1 Cited Publications
Cat. No.: HY-134797
CAS No.: 1222468-90-7
Purity:  ≥98.0%
Research Areas:  

Cancer

P-SCN-Bn-deferoxamine is a bifunctional chelating agent that can link radioactive metal nuclides (such as Zr-89) and biological targeting molecules (such as antibodies). P-SCN-Bn-deferoxamine can be used for the research of immune PET imaging .
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1
1 Cited Publications
Cat. No.: HY-129650
CAS No.: 938435-69-9
Purity:  99.08%
Synonyms: AV-45; Flobetapir
Research Areas:  

Others

Flobetapir (AV-45) may be a well-tolerated imaging agent. Flobetapir synthesizes Florbetapir (18F) that is a PET scanning radiopharmaceutical compound containing the radionuclide fluorine-18 .
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Cat. No.: HY-117756
CAS No.: 1423758-00-2
Purity:  99.10%
Synonyms: DCFPYL
Target:  

PSMA

Research Areas:  

Cancer

Piflufolastat (DCFPYL) can be used for the preparation of piflufolastat F 18 (DCFPyL F-18). Piflufolastat F-18 (DCFPyL F-18) is an 18F-labeled imaging agent. Piflufolastat F-18 can be used for positron emission tomography (PET) targeting prostate-specific membrane antigen (PSMA). Piflufolastat can be used for imaging of prostate cancer .
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Cat. No.: HY-75706
CAS No.: 763111-47-3
Research Areas:  

Cancer

N-Descyclopropanecarbaldehyde Olaparib is an analogue of Olaparib (HY-10162) containing DOTA moiety. N-Descyclopropanecarbaldehyde Olaparib is a PARP inhibitor used for synthesizing novel dual EGFR and PARP PROTAC, DP-C-4 (HY-141481) . N-Descyclopropanecarbaldehyde Olaparib can be radiolabeled with F-18 or fluorophore for positron emission tomography (PET) or optical imaging in several types of tumor .
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Cat. No.: HY-P5362
NODAGA-LM3 is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC50 = 1.3 nM). NODAGA-LM3 does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. 68Ga-labeled NODAGA-LM3 can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .
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Cat. No.: HY-P10137
CAS No.: 1801415-23-5
Synonyms: JR11
Satoreotide (JR11) is a somatostatin receptor subtype 2 (sstr2)-selective antagonist. Satoreotide can be used as a PET imaging agent when labeled with 68Ga. Satoreotide can be used for cancer research .
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Cat. No.: HY-177459
Target:  

FAP

Research Areas:  

Cancer

DOTA-2P(FAPI)2 is a dimeric FAP (fibroblast activation protein) that can be used as a PET imaging agent and a tracer for tumor therapy .
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Cat. No.: HY-164725
CAS No.: 3023869-94-2
Research Areas:  

Cancer

FAPI-mFS is a selective fibroblast activation protein (FAP) inhibitor with an IC50 of 0.0014 μM against human FAP. Through its covalent binding property with FAP, FAPI-mFS enhances its uptake and retention time in cancer cells. When radiolabeled with 68Ga, FAPI-mFS serves as a PET/CT imaging agent with superior tumor-to-background tissue contrast and lesion detection capability. When radiolabeled with 177Lu or 225Ac, FAPI-mFS induces tumor regression and inhibition in preclinical models. FAPI-mFS can be used in studies related to cancer and radionuclide-conjugated drugs (RDC) .
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Cat. No.: HY-172205
Target:  

Cytochrome P450

Research Areas:  

Cancer

CHL2310 is the inhibitor for CYP46A1 with an IC50 of 0.11 nM, and a Kd of 0.37 nM. CHL2310 can cross blood-brain barrier. CHL2310 can be used as a PET imaging agent, when labeled with radioactive 18F .
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Cat. No.: HY-141464
CAS No.: 131287-39-3
Purity:  95.03%
Synonyms: Fmoc-Asn(Ac3AcNH-beta-Glc)-OH
Research Areas:  

Cancer

Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH (Fmoc-Asn(Ac3AcNH-beta-Glc)-OH) can be used in the synthesis of silicon-fluoride acceptor (SiFA) derivatized octreotate derivatives. SiFA-octreotate analogues, as tumor imaging agents, are useful tool for the research of positron emission tomography (PET) .
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Cat. No.: HY-P5362A
NODAGA-LM3 TFA is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC50 = 1.3 nM). NODAGA-LM3 TFA does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 TFA shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. 68Ga-labeled NODAGA-LM3 TFA can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .
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Cat. No.: HY-156982
CAS No.: 1919043-65-4
Research Areas:  

Cancer

Parpi is a PET radioactive tracer with low lipotropy. Parpi can be used as a tumor imaging agent .
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Cat. No.: HY-170749
CAS No.: 2910882-32-3
Target:  

Drug Intermediate

Research Areas:  

Others

DFO-BCN is a drug intermediate, that can be used for synthesis of PET/CT imaging agent DFO-CPC634 through click chemistry .
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Cat. No.: HY-113719
CAS No.: 1071470-72-8
Target:  

Carbonic Anhydrase

Research Areas:  

Cancer

VM4-037 can be used for the synthesis of VM4-037(18F). VM4-037(18F) is a fluorinated PET imaging agent for carbonic anhydrase IX .
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Cat. No.: HY-129650R
CAS No.: 938435-69-9
Synonyms: AV-45 (Standard); Flobetapir (Standard)
Research Areas:  

Others

Flobetapir (Standard) (AV-45 (Standard)) is the analytical standard of Flobetapir (HY-129650). This product is intended for research and analytical applications. Flobetapirmay is a well-tolerated imaging agent. Flobetapir synthesizes Florbetapir (18F) that is a PET scanning radiopharmaceutical compound.
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Cat. No.: HY-147865
CAS No.: 2470024-51-0
Target:  

Galectin Apoptosis

Research Areas:  

Cancer

Apoptosis inducer 8 (Compound 7c) is a galectin-1 (gal-1) mediated apoptosis-inducing agent against global major leading lung cancer burden. Apoptosis inducer 8 significantly reduced the gal-1 protein level. Apoptosis inducer 8 is also a PET imaging agent .
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Cat. No.: HY-153127
CAS No.: 937245-42-6
Synonyms: AV-133
Research Areas:  

Neurological Disease

Florbenazine (AV-133) is a diagnostic imaging agent targeting the central nervous system monoamine transporter VMAT2, and its F-18 labeled form can be used for PET scanning. The biodistribution of [18F]Florbenazine in mice shows a high striatum/cerebellum ratio (0.48), which can be used for the diagnostic research of neurodegenerative diseases (including dementia with Lewy bodies and Parkinson's disease) .
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Cat. No.: HY-P11837
Research Areas:  

Cancer

NECT-224 is a bifunctional chelator and a nectin-4 targeting peptide conjugate. NECT-224 can be used as a PET imaging agent when labeled with 64Cu or 68Ga .
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