13 Results for "

PRS

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "PRS" in MCE Product Catalog:

Cat. No.: HY-P99605
CAS No.: 2218515-90-1
Synonyms: PRS 343

Target:  

EGFR TNF Receptor

Research Areas:  

Cancer

Cinrebafusp alfa (PRS 343) is a high affinity CD137/HER2 bispecfic anticalin-based drug. Cinrebafusp alfa binds to recombinant human HER2 (Kd=0.3 nM) and human monomeric CD137 (4-1BB; Kd=5 nM). Cinrebafusp alfa facilitates T-cell costimulation by tumor-localized, HER2-dependent 4-1BB clustering and activation, further enhancing T-cell receptor-mediated activity and leading to tumor destruction. Cinrebafusp alfa has the potential for HER2+ solid tumors research .
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Cat. No.: HY-P99935
CAS No.: 2485020-60-6
Synonyms: PRS-060; AZD1402

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Elarekibep (PRS-060) (AZD1402) is a high affinity, slowly dissociating, long-acting full antagonist of IL-4Ra. Elarekibep can be used for the research of T2 endotype asthma .
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Cat. No.: HY-117938
CAS No.: 2209057-94-1
Research Areas:  

Cancer

T-3861174 is an inhibitor of prolyl-tRNA synthetase (PRS, Aminoacyl-tRNA Synthetase) without completely inhibiting its translation process. T-3861174 activates the GCN2-ATF4 pathway and induces death in multiple tumor cell lines, including SK-MEL-2. T-3861174 demonstrated significant antitumor activity in multiple xenograft models without significantly affecting body weight .
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Cat. No.: HY-145555
CAS No.: 2241808-52-4
Purity:  98.99%
Synonyms: DWN12088
Research Areas:  

Inflammation/Immunology

Bersiporocin (DWN12088) is an orally effective prolyl-tRNA synthetase (PRS) inhibitor. Bersiporocin exerts antifibrotic effects by inhibiting collagen synthesis. Bersiporocin can be used in the research of pulmonary fibrosis .
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Cat. No.: HY-P1436
CAS No.: 11076-29-2
Target:  

HIV

Research Areas:  

Infection

Acetyl-pepstatin is a potent classical inhibitor of aspartic proteases (PRs) with XMRV PR and HIV-1 PR Ki values of 712 nM and 13 nM .
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Cat. No.: HY-W275220
CAS No.: 3241-03-0
Research Areas:  

Infection

PEA-NBOMe hydrochloride (Compound 21) is a competitive phenylalanyl-tRNA synthetase (PRS) inhibitor (Ki=0.92 μM), which is found in Escherichia coli. PEA-NBOMe hydrochloride is promising for research of antibacterial or antiviral agents .
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Cat. No.: HY-RS15825
Research Areas:  

Others

WNK3 Human Pre-designed siRNA Set A contains three designed siRNAs for WNK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P99803
CAS No.: 2145123-44-8
Synonyms: VAL-1221

Target:  

Glycosidase

Research Areas:  

Others

Clervonafusp alfa (VAL-1221) is a fusion protein targeting both cytosolic and lysosomal glycogen. Clervonafusp alfa is comprised of the Fab portion of a cell-penetrating antibody and recombinant human acid alpha glucosidase (rhGAA), the former utilizing the nucleoside transporter ENT-2 to gain access to the cytosol, and the latter enters lysosomes via mannose-6-phosphate receptors (M6PRs). Clervonafusp alfa can be used for late-onset Pompe disease research .
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Cat. No.: HY-P5415
CAS No.: 127134-13-8
Target:  

HIV

Research Areas:  

Others

DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is a biological active peptide. (DABCYL-GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS is also called HIV protease substrate I in some literature. It is widely used for the continuous assay for HIV protease activity. The 11-Kd protease (PR) encoded by the human immunodeficiency virus 1 (HIV-1) is essential for the correct processing of viral polyproteins and the maturation of infectious virus, and is therefore a target for the design of selective acquired immunodeficiency syndrome (AIDS) therapeutics. The FRET-based fluorogenic substrate is derived from a natural processing site for HIV-1 PR. Incubation of recombinant HIV-1 PR with the fluorogenic substrate resulted in specific cleavage at the Tyr-Pro bond and a time-dependent increase in fluorescence intensity that is linearly related to the extent of substrate hydrolysis. The fluorescence quantum yields of the HIV-1 PR substrate in the FRET assay increased by 40.0- and 34.4-fold, respectively, per mole of substrate cleaved. Because of its simplicity and precision in the determination of reaction rates required for kinetic analysis, this substrate offers many advantages over the commonly used HPLC or electrophoresis-based assays for peptide substrate hydrolysis by retroviral PRs. Abs/Em = 340nm/490nm.)
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Cat. No.: HY-P77156
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Ribose-Phosphate Pyrophosphokinase 2; PPRibP; PRS-II; PRPS2
Species:  
Source:  
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Cat. No.: HY-P71108
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Ribose-Phosphate Pyrophosphokinase 2; PPRibP; Phosphoribosyl Pyrophosphate Synthase II; PRS-II; PRPS2
Species:  
Source:  
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Cat. No.: HY-P703424
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Immune protein Tsi3; Anti-toxin protein Tsi3; tsi3; Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Species:  
Source:  
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Cat. No.: HY-P700595
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PRPS1; phosphoribosyl pyrophosphate synthetase 1; deafness, X linked 2, perceptive, congenital , DFN2; ribose-phosphate pyrophosphokinase 1; CMTX5; DFNX1; PRS I; ribose phosphate diphosphokinase 1;
Species:  
Source:  
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