7 Results for "

Peptide T-1

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Peptide T-1" in MCE Product Catalog:

loading...
    loading...
Cat. No.: HY-P5488
CAS No.: 329696-53-9
Target:  

Inhibitory Antibodies

Research Areas:  

Others

BDC2.5 Mimotope 1040-63 is a biological active peptide. (The TCR transgenic model (BDC2.5) mimitope was used in type 1 diabetes (T1D) study. T1D is an autoimmune disease in which T cells mediate damage to pancreatic islet b cells. T1D is caused by autoreactive T cell destruction of insulin-producing cells. BDC2.5 mimotope was utilized to support the study on antigen presentation of antigenic peptides to islet autoantigen-specific T cells.)
loading...
    loading...
Cat. No.: HY-P11255
Target:  

MDM-2/p53

Research Areas:  

Cancer

SPDI-48-T1 is a lysine-stapled peptide. SPDI-48-T1 exhibits discernible binding affinities for MDM2 and MDMX, with Kd values of 396 nM and 456 nM, respectively. SPDI-48-T1 exhibits anticancer activity against breast cancer, colorectal cancer, non-small cell lung cancer, cervical cancer, and malignant melanoma .
loading...
    loading...
Cat. No.: HY-P11298
CAS No.: 2120397-85-3
d-T101 peptide, a human hormone-peptide, is a T1/ST2 receptor ligand. d-T101 peptide binds to the T1/ST2 receptor and activates caspases 8, 9 and 3 mediated apoptosis, together with activation of JNKinase and p38 MAPKinase. d-T101 peptide also changes Golgi structural with function loss and downregulation of the endoplasmic reticulum (ER) stress repair mechanism. d-T101 peptide has immunostimulatory and anticancer activity, selectively induces apoptosis in proliferating cancer cells and increases IL-2 and IFN-γ expression as well as the recruitment of NK cells and M1 macrophages to the tumor site .
loading...
    loading...
Cat. No.: HY-P11887
CAS No.: 1174559-81-9
VHPKQHR is a peptide-based delivery enhancer that binds to VCAM-1. VHPKQHR enables intracellular internalization of relevant nanomaterials and facilitates the targeted delivery of miRNA inhibitors to inflamed endothelial cells and endothelial cells activated by disturbed flow. When conjugated with magnetic mesoporous silica nanoparticles, VHPKQHR achieves targeted accumulation at atherosclerotic plaque sites. When displayed on the surface of polyelectrolyte complex micelles, VHPKQHR enhances the relevant effects of anti-miR-92a in Apoe -/- mice. When conjugated with ultrasmall superparamagnetic iron oxide nanoparticles, VHPKQHR forms a contrast agent for T1-weighted magnetic resonance imaging. VHPKQHR can be used in research related to atherosclerosis, stenosis and rheumatoid arthritis .
loading...
    loading...
Cat. No.: HY-P12360
Research Areas:  

Cancer

4T1pep1 is a tumor-homing cyclic peptide obtained through phage display screening. 4T1pep1 binds to mouse 4T1 triple-negative breast cancer cells and human MDA-MB-231 triple-negative breast cancer cells. 4T1pep1 is useful for triple-negative breast cancer-related research .
loading...
    loading...
Cat. No.: HY-P10492
Target:  

Inhibitory Antibodies

Research Areas:  

Others Metabolic Disease

Tregitope 289 is a peptide derived from the Fc region of immunoglobulin G (IgG) and is a highly conserved T cell epitope that stimulates the expansion of natural regulatory T cells. Co-delivery of Tregitope 289 with type 1 diabetes (T1D) antigens delays the development of hyperglycemia and reduces the incidence of diabetes in the NOD mouse model. Tregitope 289 can be used to study T1D and other autoimmune diseases .
loading...
    loading...