SPDI-48-T1
SPDI-48-T1 is a lysine-stapled peptide. SPDI-48-T1 exhibits discernible binding affinities for MDM2 and MDMX, with Kd values of 396 nM and 456 nM, respectively. SPDI-48-T1 exhibits anticancer activity against breast cancer, colorectal cancer, non-small cell lung cancer, cervical cancer, and malignant melanoma.
For research use only. We do not sell to patients.
- Formula: C91H129N21O20
- Molecular Weight:1837.13
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Kd: 396 nM (MDM2) and 456 nM (MDMX)[1]
Chemical Information
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Molecular Weight 1837.13
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Formula C91H129N21O20
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Sequence
Ac-Leu-Thr-Phe-Lys-His-Tyr-Trp-Lys-Gln-Leu-Thr-Ser-Ala-Ala-NH2 (Lys stapled via 1,3-bismethylenebenzene)
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Sequence Shortening
Ac-LTFKHYWKQLTSAA-NH2 (Lys stapled via 1,3-bismethylenebenzene)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)