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Results for "

Podophyllum peltatum

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Bcl-2 Family (1) Caspase (1) Fungal (1) PARP (1)
By Research Areas:	Cancer (3)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

4'-Demethylpodophyllotoxin	Others	Cancer
4'-Demethylpodophyllotoxin is an aryltetralin lignin contained in the root of Podophyllum hexandrum and P. peltatum. 4'-Demethylpodophyllotoxin exhibits cytotoxic potential in diverse cancer cell lines .

(-)-Epipodophyllotoxin	Apoptosis	Cancer
(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells isolated from American mayapple Podophyllum peltatum, with GI₅₀s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vitro .

α-Peltatin	Fungal	Others
α-Peltatin is an aryl lignan. α-Peltatin has anticancer and antifungal activity. α-Peltatin inhibits DNA topoisomerase and tubulin polymerization .

4-Demethyldeoxypodophyllotoxin	Others	Others
4-Demethyldeoxypodophyllotoxin is an aryltetralin lignan that can be found in Podophyllum peltatum .

(-)-β-Peltatin β-Peltatin	Apoptosis Bcl-2 Family Caspase PARP	Cancer
(-)-β-Peltatin is an aryltetrahydronaphthalene lignan. (-)-β-Peltatin exhibits antitumor activity and cytotoxicity against pancreatic cancer cells. (-)-β-Peltatin induces G2/M cell cycle arrest and apoptosis in pancreatic cancer cells. (-)-β-Peltatin inhibits the growth of subcutaneous xenografts of pancreatic cancer cells in nude mice. (-)-β-Peltatin can be used in pancreatic cancer-related research .

4'-Demethylpodophyllotoxin	Monophenols Classification of Application Fields Sinopodophyllum hexandrum (Royle) Ying Lignans Phenols Phenylpropanoids Plants Berberidaceae Disease Research Fields Source Classification Cancer	Others
4'-Demethylpodophyllotoxin is an aryltetralin lignin contained in the root of Podophyllum hexandrum and P. peltatum. 4'-Demethylpodophyllotoxin exhibits cytotoxic potential in diverse cancer cell lines .

(-)-Epipodophyllotoxin	other families Classification of Application Fields Lignans Phenylpropanoids Plants Disease Research Fields Cancer Source Classification	Apoptosis
(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells isolated from American mayapple Podophyllum peltatum, with GI₅₀s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vitro .

α-Peltatin	Podophyllum peltatum L. Lignans Phenylpropanoids Plants Berberidaceae Source Classification	Fungal
α-Peltatin is an aryl lignan. α-Peltatin has anticancer and antifungal activity. α-Peltatin inhibits DNA topoisomerase and tubulin polymerization .

4-Demethyldeoxypodophyllotoxin	Sinopodophyllum hexandrum (Royle) Ying Lignans Phenylpropanoids Plants Berberidaceae Source Classification	Others
4-Demethyldeoxypodophyllotoxin is an aryltetralin lignan that can be found in Podophyllum peltatum .

(-)-β-Peltatin β-Peltatin	Structural Classification Lignans Dysosma versipellis (Hance) M. Cheng ex Ying Phenylpropanoids Plants Berberidaceae Source Classification	Apoptosis Bcl-2 Family Caspase PARP
(-)-β-Peltatin is an aryltetrahydronaphthalene lignan. (-)-β-Peltatin exhibits antitumor activity and cytotoxicity against pancreatic cancer cells. (-)-β-Peltatin induces G2/M cell cycle arrest and apoptosis in pancreatic cancer cells. (-)-β-Peltatin inhibits the growth of subcutaneous xenografts of pancreatic cancer cells in nude mice. (-)-β-Peltatin can be used in pancreatic cancer-related research .

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