25 Results for "

Pregnant rats

" in MedChemExpress (MCE) Product Catalog:
Products (25)

25 Results for "Pregnant rats" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99459
CAS No.: 909110-25-4
Synonyms: BG 9924; TT-47

Target:  

TNF Receptor CXCR

Research Areas:  

Inflammation/Immunology

Baminercept (BG 9924; TT-47) is an Ig fusion protein targeting the lymphotoxin β receptor (LTβR). Baminercept effectively regulates subsets of circulating immune cells by inhibiting LIGHT, LT-α1β2 and their receptors. Baminercept also increases blood lymphocyte counts and reduces plasma CXCL13 levels. Baminercept carries a high risk of hepatotoxicity. Baminercept can be used in research on rheumatoid arthritis and primary Sjögren's syndrome .
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1
1 Cited Publications
Cat. No.: HY-115584
CAS No.: 103055-07-8
Purity:  99.57%
Research Areas:  

Infection

Lufenuron is an orally active lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods. Lufenuron induces reproductive toxicity, genotoxic effects and oxidative stresses in pregnant albino rats and their fetuses .
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1
1 Cited Publications
Cat. No.: HY-133813A
CAS No.: 72296-47-0
Purity:  ≥95.0%
Apovincaminic acid hydrochloride salt is the major metabolite of Vinpocetine (HY-13295), with blood-brain barrier permeability and oral activity. Apovincaminic acid hydrochloride salt is detectable in the plasma of pregnant rabbits after oral administration of Vinpocetine. Apovincaminic acid hydrochloride salt is absorbable from all segments of the gastrointestinal tract of Norway rat, with the stomach as the primary absorption site, and is excreted via urine and feces. Apovincaminic acid hydrochloride salt is used in the research of cerebrovascular diseases .
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Cat. No.: HY-N0120
CAS No.: 65914-17-2
Synonyms: (E/Z)-Piceid
(E/Z)-Polydatin ((E/Z)-Piceid) is a mixture of the E/Z configurations of Polydatin (HY-N0120A). Polydatin can be isolated from Polygonum cuspidatum, grapes, peanuts, red wine, hop pellets, cocoa-containing products and chocolate products. Polydatin exhibits multiple biological properties, such as anti-platelet aggregation, anti-low-density lipoprotein oxidation, cardioprotective activity, anti-inflammatory and immunomodulatory functions. Polydatin shows favorable cytotoxic effects against various tumor cell lines, including cervical cancer cells, liver cancer cells, and nasopharyngeal carcinoma cells .
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Cat. No.: HY-W019815
CAS No.: 759-73-9
Synonyms: ENU; N-Nitroso-N-ethylurea
Target:  

DNA/RNA Synthesis

Research Areas:  

Neurological Disease Cancer

N-Ethyl-N-nitrosourea (ENU) is a DNA alkylating agent. N-Ethyl-N-nitrosourea induces leukemia by alkylating nucleobases, disrupting DNA, and resulting in bone marrow suppression and the formation of leukemic cells. N-Ethyl-N-nitrosourea is teratogenic in vivo, inducing tumor formation and paw malformations in pregnant rats. N-Ethyl-N-nitrosourea cause central nervous system (CNS) tumors and genetic disorders .
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Cat. No.: HY-116954
CAS No.: 21087-64-9
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

Metribuzin is a low-cost non-selective herbicide belonging to the chemical class of triazinones. Metribuzin inhibits plant DNA synthesis and acts on photosystem II, ultimately suppressing photosynthesis. Metribuzin provides excellent control of important annual grass and broadleaf weeds .
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Cat. No.: HY-W011787
CAS No.: 74-31-7
Synonyms: N,N′-Diphenyl-p-phenylenediamine
Research Areas:  

Metabolic Disease

DPPD (N,N′-Diphenyl-p-phenylenediamine) is an orally active antioxidant. DPPD also acts as a toxic substance and pregnancy disruptor .
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Cat. No.: HY-13570B
CAS No.: 987-24-6
Purity:  99.38%
Research Areas:  

Others

Betamethasone acetate is a glucocorticoid with prenatal application for preventing respiratory distress syndrome (RDS) in premature infants. Betamethasone acetate exhibits dose-dependent effects on somatic and brain development in offspring when administered prenatally to pregnant rats. Betamethasone acetate can be used for the study of antenatal intervention .
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Cat. No.: HY-P2786A
CAS No.: 741738-57-8
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Phrixotoxin 2 is a Kv4 family potassium channel inhibitor, with Ki values in rats of 120 nM for Kv4.2, 110 nM for Kv4.3, and 230 nM for Kv4.1. Phrixotoxin 2 mediates voltage-dependent inhibition of Kv4.2 and Kv4.3 currents, and voltage-independent inhibition of Kv4.1 currents. Phrixotoxin 2 fails to inhibit A-type K + currents in visceral dorsal root ganglion neurons. Phrixotoxin 2 induces contraction of non-pregnant uterine smooth muscle and triggers orofacial cold hyperalgesia in rats. Phrixotoxin 2 can distinguish the contribution of Kv4 subunits to A-type K + currents in different subsets of sensory neurons. Phrixotoxin 2 can be used in research related to chronic pain and trigeminal neuropathic pain .
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Cat. No.: HY-P0284A
Target:  

MMP

Research Areas:  

Metabolic Disease

C-telopeptide TFA is a cross-linked peptide of type I collagen that is released during bone resorption and correlates with bone mineral density (BMD). C-telopeptide TFA can be used in studies related to postmenopausal osteoporosis .
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Cat. No.: HY-P0284
CAS No.: 162929-64-8
Target:  

MMP

Research Areas:  

Metabolic Disease

C-telopeptide is a cross-linked peptide of type I collagen that is released during bone resorption and correlates with bone mineral density (BMD). C-telopeptide can be used in studies related to postmenopausal osteoporosis .
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Cat. No.: HY-156481
CAS No.: 2126-63-8
Target:  

Cytochrome P450

Research Areas:  

Others

SU-8000 is an inhibitor that selectively targets 17α-hydroxylase and C17-20-lyase in rat testes. When administered to pregnant rats, SU-8000 can cause hypospadias in male fetuses .
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Cat. No.: HY-W018359
CAS No.: 20018-09-1
Synonyms: Diiodomethyl p-tolyl sulfone
Research Areas:  

Infection

Tolyl diiodomethyl sulfone is an organic antibacterial agent that does not cause significant changes in the number of resorbed fetuses, the number of dead fetuses, or the body weight of live fetuses in rats .
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Cat. No.: HY-164034
CAS No.: 299-61-6
Target:  

nAChR

Research Areas:  

Endocrinology

Ganglefene is a blocker for n-choline receptor, which leads to the sexual dysfunction in the offspring in adulthood, when administrated to pregnant rats .
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Cat. No.: HY-157495
CAS No.: 499149-94-9
Research Areas:  

Endocrinology

EP3 antagonist 6 (compound 5) is a potent, orally and selective EP3 receptor antagonist, with an IC50 of 1.9 nM. EP3 antagonist 6 can inhibits PGE2-induced (HY-101952) uterine contraction in pregnant rats .
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Cat. No.: HY-13570BS1
Betamethasone acetate-d5 is deuterium labeled Betamethasone acetate (HY-13570B). Betamethasone acetate is a glucocorticoid with prenatal application for preventing respiratory distress syndrome (RDS) in premature infants. Betamethasone acetate exhibits dose-dependent effects on somatic and brain development in offspring when administered prenatally to pregnant rats. Betamethasone acetate can be used for the study of antenatal intervention .
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Cat. No.: HY-13570BR
CAS No.: 987-24-6
Research Areas:  

Others

Betamethasone acetate (Standard) is the analytical standard of Betamethasone acetate (HY-13570B). This product is intended for research and analytical applications. Betamethasone acetate is a glucocorticoid with prenatal application for preventing respiratory distress syndrome (RDS) in premature infants. Betamethasone acetate exhibits dose-dependent effects on somatic and brain development in offspring when administered prenatally to pregnant rats. Betamethasone acetate can be used for the study of antenatal intervention .
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Cat. No.: HY-15018A
CAS No.: 785048-28-4
Target:  

Oxytocin Receptor

Research Areas:  

Endocrinology

SSR126768A free base is an orally active antagonist for oxytocin receptor, with Ki of 0.44 nM. SSR126768A free base is a tocolytic agent, that antagonizes the Oxytocin (HY-17571)-induced intracellular Ca 2+ increase and prostaglandin release in human uterine smooth muscle cells, inhibits thus the Oxytocin (HY-17571)-induced uterine contraction and delays parturition in pregnant rats in labor .
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Cat. No.: HY-133813AR
CAS No.: 72296-47-0
Apovincaminic acid hydrochloride salt (Standard) is the analytical standard of Apovincaminic acid hydrochloride salt (HY-133813A). This product is intended for research and analytical applications. Apovincaminic acid hydrochloride salt is the major metabolite of Vinpocetine (HY-13295), with blood-brain barrier permeability and oral activity. Apovincaminic acid hydrochloride salt is detectable in the plasma of pregnant rabbits after oral administration of Vinpocetine. Apovincaminic acid hydrochloride salt is absorbable from all segments of the gastrointestinal tract of Norway rat, with the stomach as the primary absorption site, and is excreted via urine and feces. Apovincaminic acid hydrochloride salt is used in the research of cerebrovascular diseases .
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Cat. No.: HY-133813S
Apovincaminic acid-d4 is the deuterated-labeled Apovincaminic acid (HY-133813). Apovincaminic acid is the major metabolite of Vinpocetine (HY-13295), with blood-brain barrier permeability and oral activity. Apovincaminic acid is detectable in the plasma of pregnant rabbits after oral administration of Vinpocetine. Apovincaminic acid is absorbable from all segments of the gastrointestinal tract of Norway rat, with the stomach as the primary absorption site, and is excreted via urine and feces. Apovincaminic acid is used in the research of cerebrovascular diseases .
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