16 Results for "

RNP

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "RNP" in MCE Product Catalog:

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1 Cited Publications
Cat. No.: HY-N6025
CAS No.: 112747-98-5
Clemastanin B, a lignin, has potent anti-influenza activities by inhibiting the virus multiplication, prophylaxsis and blocking the virus attachment. Clemastanin B targets viral endocytosis, uncoating or ribonucleoprotein (RNP) export from the nucleus. Clemastanin B has antioxidant and anti-inflammatory activities .
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Cat. No.: HY-175469
CAS No.: 2894060-67-2
Target:  

Influenza Virus

Research Areas:  

Infection

VNT-101 is an orally active influenza A (IAV) inhibitor. VNT-101 disrupts NP-NP PPI to block NP oligomerization and destabilize the viral ribonucleoprotein (RNP) complex, with potent antiviral activity across multiple influenza A subtypes. VNT-101 exhibits EC50 values of 4-5 nM in cellular cytopathic effect (CPE) assay, 4-8 nM in neuraminidase (NA) assay, and 21-45 nM in RNP assay. VNT-101 demonstrates robust in vivo antiviral efficacy in mice infected with lethal H1N1 virus. VNT-101 can be used for the study of influenza A infection .
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Cat. No.: HY-P10068
CAS No.: 476169-12-7
Target:  

Inhibitory Antibodies

Research Areas:  

Others

LAH5 is an amphipathic cell-penetrating peptide. LAH5 forms nanocomplexes with both RNP and RNP/HDR cargo .
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Cat. No.: HY-P10680
Target:  

Liposome

Research Areas:  

Others

TFE-IDAtp1-LinA is a highly potent amphiphilic carrier, containing a trifluoroethyl-iminodiacetic acid analog of Stp. TFE-IDAtp1-LinA, formed nanoparticles with Cas9 RNP/ssDNA, achieved enhanced green fluorescent protein knockouts with an ED50 of 0.38 nM Cas9/sgRNA ribonucleoproteins (RNP) .
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Cat. No.: HY-P10068A
Target:  

Inhibitory Antibodies

Research Areas:  

Others

LAH5 TFA is an amphipathic cell-penetrating peptide. LAH5 THA forms nanocomplexes with both RNP and RNP/HDR cargo .
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Cat. No.: HY-RS12108
Research Areas:  

Others

RNPS1 Human Pre-designed siRNA Set A contains three designed siRNAs for RNPS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS12103
Research Areas:  

Others

RNPC3 Human Pre-designed siRNA Set A contains three designed siRNAs for RNPC3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-111026
CAS No.: 950381-32-5
Target:  

Influenza Virus

Research Areas:  

Infection

PPQ-581 is an anti-influenza agent with an EC50 of 1 μM for preventing virus-induced cytopathic effects. PPQ-581 inhibits viral protein synthesis. PPQ-581 blocks the RNP nuclear export and cytoplasmic RNP aggregation .
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Cat. No.: HY-187563
Research Areas:  

Infection

RNP-11 is a selective COX-2 inhibitor with an IC50 of 42.85 μg/mL against human COX-2, and also acts as a bactericide and anti-inflammatory agent. RNP-11 inhibits the production of pro-inflammatory cytokines (IL-6, TNF-α, IL-1β, disrupts bacterial cell membranes and induces bacterial cell death. RNP-11 exhibits activity against strains of Staphylococcus and Enterococcus, including Methicillin (HY-121544)-resistant Staphylococcus aureus and Vancomycin (HY-B0671)-resistant Enterococcus faecium. RNP-11 reduces the load of Staphylococcus aureus, exerting dual effects of pathogen clearance and inflammatory response alleviation in a mouse skin infection model,. RNP-11 can be used in research related to infections caused by Staphylococcus, Staphylococcus aureus and Enterococcus faecium .
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Cat. No.: HY-185702
CAS No.: 3069451-89-1
DMT-dU (Crotonic hexanediamine 3-(benzoylthio) propanoic)-CE phosphoramidite is a phosphoramidite reagent used to synthesize chemically modified guide RNAs for forming CRISPR-Cas RNP conjugates with Cas proteins. DMT-dU (Crotonic hexanediamine 3-(benzoylthio) propanoic)-CE phosphoramidite can be applied in research on antiviral agents, cancer, neurodegenerative diseases and genetic diseases .
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Cat. No.: HY-P11639
CAS No.: 380480-77-3
Research Areas:  

Others

ppTG21 is an endosomolytic agent and inducer. ppTG21 can facilitate endosomal escape of Cas9-2lig-1NLS and Cas9-ASGPrL ribonucleoproteins (RNPs) to enable receptor-facilitated, cell-type specific gene editing in cancer cells without electroporation or transfection reagents. ppTG21 can be used for the research of gene editing .
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Cat. No.: HY-P87162
Synonyms: Heterogeneous nuclear ribonucleoprotein A2 antibody; Heterogeneous nuclear ribonucleoprotein A2/B1 antibody; Heterogeneous nuclear ribonucleoprotein B1 antibody; Heterogeneous nuclear ribonucleoproteins A2/B1 antibody; hnRNP A2 / hnRNP B1 antibody; hnRNP A2 antibody; hnRNP A2/B1 antibody; hnRNP B1 antibody; hnRNP-A2 antibody; hnRNP-B1 antibody; Heterogeneous nuclear ribonucleoprotein A2 antibody; Heterogeneous nuclear ribonucleoprotein A2/B1 antibody; Heterogeneous nuclear ribonucleoprotein B1 antibody; Heterogeneous nuclear ribonucleoproteins A2/B1 antibody; hnRNP A2 / hnRNP B1 antibody; hnRNP A2 antibody; hnRNP A2/B1 antibody; hnRNP B1 antibody; hnRNP-A2 antibody; hnRNP-B1 antibody; hnRNPA2 antibody; HnRNPa2b1 antibody; hnRNPB1 antibody; HNRPA2 antibody; HNRPA2B1 antibody; HNRPB1 antibody; Nuclear ribonucleoprotein particle A2 protein antibody; RNP A2 antibody; RNP B1 antibody; RNP-A2 antibody; RNP-B1 antibody; RNPA2 antibody; RNPB1 antibody; ROA2_HUMAN antibody; SNRPB1 antibody;

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF, FC, IF-Tissue

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-184249
CAS No.: 1145869-35-7
Target:  

RSV DNA/RNA Synthesis

Research Areas:  

Infection

4'-C-Azido-2'-deoxy-2'-fluorocytidine is an antiviral agent. 4'-C-Azido-2'-deoxy-2'-fluorocytidine potently inhibits RNA synthesis of crude RSV RNP complexes with an IC50 of 0.1 μM. 4'-C-Azido-2'-deoxy-2'-fluorocytidine inhibits RSV replication in a subgenomic RSV replicon system. 4'-C-Azido-2'-deoxy-2'-fluorocytidine can be used for the research of respiratory syncytial virus (RSV) infection .
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Cat. No.: HY-P701154
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SNRPA; Mud1; Small Nuclear Ribonucleoprotein Polypeptide A; U1 SnRNP A; U1-A; U1 Small Nuclear RNP-Specific A; U1A; U1 SnRNP-Specific Protein A; U1 Small Nuclear Ribonucleoprotein A
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P703336
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RBM38; DJ800J21.2; Prev. RNPC1; Seb4B; HSRNASEB; RNA-Binding Region (RNP1, RRM) Containing 1; RNA-Binding Region-Containing Protein 1; RNA-Binding Motif Protein 38; SsDNA-Binding Protein SEB4; CLL-Associated Antigen KW-5; RNA-Binding Protein 38; SEB4; RNA
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-180525
Target:  

Influenza Virus

Research Areas:  

Infection

PB2-IN-2 is an orally active PB2 inhibitor with RNA-dependent RNA Polymerase (RNP) IC50 = 0.2 nM, LRA (Ligand Receptor Assay) EC50 = 0.8 nM, Cytopathic Effect (CPE) EC50 = 0.1 nM. PB2-IN-2 exhibits broad-spectrum, nanomolar antiviral potency against a panel of influenza A strains (including H1N1pdm09, Lyon/1337/2007/H1N1, Tex12-Like/H3N2, PR/8/34/H1N1, WSN/1933/H1N1, rPR8(H1N1)/H7N9 with EC50 = 1.5, 3.6, 3.7, 13.8, 2.9 and 9.8 nM and all the CC50 values > 2 μM. PB2-IN-2 possesses an excellent pharmacokinetic profile and metabolic stability. PB2-IN-2 can be used for anti-influenza research .
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