33 Results for "

SCG

" in MedChemExpress (MCE) Product Catalog:
Products (33)

33 Results for "SCG" in MCE Product Catalog:

Cat. No.: HY-P99899
CAS No.: 2052591-32-7
Synonyms: PR-1498487

Target:  

ADC Antibodies

Research Areas:  

Cancer

Samrotamab (PR-1498487) is a humanized IgG1-κ chimeric monoclonal antibody targeting LRRC15, with a Kd of 5.42 nM for human LRRC15. Samrotamab can be used to synthesize antibody-drug conjugates (ADC). Samrotamab disrupts the LRRC15-SCG5 signaling module, binds to a membrane-proximal conformational epitope within the C-terminal leucine-rich repeat region of LRRC15, and binds to the lateral edge of the LRR solenoid while leaving the canonical concave β-sheet surface fully exposed. Samrotamab reduces the viability of bladder cancer cells, inhibits clonogenic growth, impairs cell migration, and compromises cell invasion. Samrotamab induces compensatory upregulation of LRRC15 transcripts while suppressing the expression of SCG5 mRNA. Samrotamab is applicable to research related to urothelial carcinoma, sarcoma, osteosarcoma, and undifferentiated pleomorphic sarcoma .
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Cat. No.: HY-W014700
CAS No.: 7412-78-4
Synonyms: H-Gly-Glu-OH; Gly-Glu
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

Glycyl-L-glutamic acid is a neurotrophic factor (NF) in vivo, and exerts function of maintenance of AChE content and activity. Glycyl-L-glutamic acid doesn’t act directly on AChE synthesis, and may prevent preganglionic neuronal degeneration .
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Cat. No.: HY-RS12503
Research Areas:  

Others

SCG5 Human Pre-designed siRNA Set A contains three designed siRNAs for SCG5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS12501
Research Areas:  

Others

SCG2 Human Pre-designed siRNA Set A contains three designed siRNAs for SCG2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS12502
Research Areas:  

Others

SCG3 Human Pre-designed siRNA Set A contains three designed siRNAs for SCG3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS19380
Research Areas:  

Others

Scg2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Scg2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS22319
Research Areas:  

Others

Scg5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Scg5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS25649
Research Areas:  

Others

Scg3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Scg3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS28841
Research Areas:  

Others

Scg5 Rat Pre-designed siRNA Set A contains three designed siRNAs for Scg5 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Cat. No.: HY-113985
CAS No.: 59939-16-1
Synonyms: LD 3098
Cirazoline (LD 3098) is a doul agonist of Presynaptic imidazoline receptors (R(i-pre)) and α-adrenoceptor (R(α)). Cirazoline (30 μM) suppresses M current in SCG neurons cultured overnight .
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Cat. No.: HY-RS19160
Research Areas:  

Others

Scg3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Scg3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS25872
Research Areas:  

Others

Scg2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Scg2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-184689
CAS No.: 1311892-52-0
Target:  

LILRB

Research Areas:  

Cancer

ORS-14 is a LILRB4/ILT3 ligand with a Kd of 85.2 nM for human receptors. ORS-14 blocks SCG2-mediated LILRB4 signaling pathway, reverses SCG2-mediated immunosuppression, restores cytokine production, reduces tumor cell viability, recovers cytotoxic T cell function, and increases the frequency of granzyme B + CD8 + T cells. ORS-14 can be used in research related to colorectal cancer and acute myeloid leukemia .
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Cat. No.: HY-P74568
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Secretogranin-3; Secretogranin III; SgIII; SCG3
Species:  
Source:  
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Cat. No.: HY-183941
CAS No.: 713080-84-3
Target:  

PAK

Research Areas:  

Cancer

SPU-106 is a p21 activated kinase 4 (PAK4) inhibitor with a target IC50 of 21.36 μM. SPU-106 selectively binds to the C-terminal kinase domain of PAK4 to inhibit its kinase activity. SPU-106 inhibits the PAK4/LIMK1/cofilin and PAK4/SCG10 signaling pathways. SPU-106 inhibits invasion of gastric cancer cells and lacks cytotoxicity against cancer cells. SPU-106 can be used for the research of gastric cancer .
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Cat. No.: HY-P78352
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Secretogranin-3; Secretogranin III; SCG3; SGIII; UNQ2502/PRO5990
Species:  
Source:  
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Cat. No.: HY-P700824
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Secretogranin-3; Secretogranin III; SCG3; SGIII; UNQ2502/PRO5990
Species:  
Source:  
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Cat. No.: HY-P83789
Synonyms: MEAI; SCG2

Host:  

Mouse

Application:  

IHC-P, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P81928
Synonyms: MEN1; SCG2; Menin

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P703163
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SCG2
Species:  
Source:  
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