20 Results for "

SIGLEC10

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "SIGLEC10" in MCE Product Catalog:

Cat. No.: HY-P991480
ONC-841 is a blood-brain barrier-permeable, humanized monoclonal antibody targeting SIGLEC10. As an immune checkpoint inhibitor, ONC-841 restores the functions of immune effector cells such as T cells and enhances anti-tumor immune responses by blocking inhibitory signals mediated by SIGLEC10. ONC-841 restores the phagocytic and migratory activities of microglia, and promotes the phagocytosis of Amyloid-β and Tau protein aggregates by microglia. ONC-841 is applicable to research related to solid tumors and Alzheimer's disease .
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Cat. No.: HY-P10091
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

CD24/Siglec-10 blocking peptide, CSBP can not only block the interaction of CD24/Siglec-10 but also PD-1/PD-L1. CD24/Siglec-10 blocking peptide, CSBP can induce the phagocytosis of tumor cell .
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Cat. No.: HY-P99928
CAS No.: 2574508-57-7
Synonyms: MK 7110; CD24 Fc

Research Areas:  

Cancer

Efprezimod alfa (MK 7110; CD24 Fc) is a humanized CD24-Fc fusion protein. Efprezimod alfa enhances the interaction between CD24 and Siglec-10, thereby regulating the response of innate immune cells to damage-associated molecular patterns, inhibiting the activation of antigen-presenting cells and subsequent inflammatory responses. Efprezimod alfa is applicable to the research of acute graft-versus-host disease and acquired immunodeficiency syndrome .
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Cat. No.: HY-RS12898
Research Areas:  

Others

SIGLEC10 Human Pre-designed siRNA Set A contains three designed siRNAs for SIGLEC10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS26351
Research Areas:  

Others

Siglec10 Rat Pre-designed siRNA Set A contains three designed siRNAs for Siglec10 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P992303

Research Areas:  

Inflammation/Immunology

Anti-Siglec-10/CD24 Antibody is a monoclonal antibody targeting Siglec-10. It can be used in ELISA, FACS, and functional assays. Isotype controls for Anti-Siglec-10/CD24 Antibody can be found in Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P704295
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIGLEC10; SIGLEC-Like Protein 2; Sialic Acid Binding Ig Like Lectin 10; SIGLEC-Like Gene 2; SLG2; MGC126774; SIGLEC-10; Sialic Acid Binding Ig-Like Lectin 10; PRO940; SIGLEC10 Protein; Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7; SIGLEC-10; Sia
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P72411
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIGLEC10; SIGLEC-Like Protein 2; Sialic Acid Binding Ig Like Lectin 10; SIGLEC-Like Gene 2; SLG2; MGC126774; SIGLEC-10; Sialic Acid Binding Ig-Like Lectin 10; PRO940; SIGLEC10 Protein; Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7; SIGLEC-10; Sia
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76642
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIGLEC10; SIGLEC-Like Protein 2; Sialic Acid Binding Ig Like Lectin 10; SIGLEC-Like Gene 2; SLG2; MGC126774; SIGLEC-10; Sialic Acid Binding Ig-Like Lectin 10; PRO940; SIGLEC10 Protein; Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7; SIGLEC-10; Sia
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P72476
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIGLEC10; SIGLEC-Like Protein 2; Sialic Acid Binding Ig Like Lectin 10; SIGLEC-Like Gene 2; SLG2; MGC126774; SIGLEC-10; Sialic Acid Binding Ig-Like Lectin 10; PRO940; SIGLEC10 Protein; Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7; SIGLEC-10; Sia
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704878
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SIGLEC10; SIGLEC-Like Protein 2; Sialic Acid Binding Ig Like Lectin 10; SIGLEC-Like Gene 2; SLG2; MGC126774; SIGLEC-10; Sialic Acid Binding Ig-Like Lectin 10; PRO940; SIGLEC10 Protein; Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7; SIGLEC-10; Sia
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P78571
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIGLEC10; SIGLEC-Like Protein 2; Sialic Acid Binding Ig Like Lectin 10; SIGLEC-Like Gene 2; SLG2; MGC126774; SIGLEC-10; Sialic Acid Binding Ig-Like Lectin 10; PRO940; SIGLEC10 Protein; Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7; SIGLEC-10; Sia
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P70448
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIGLEC10; SIGLEC-Like Protein 2; Sialic Acid Binding Ig Like Lectin 10; SIGLEC-Like Gene 2; SLG2; MGC126774; SIGLEC-10; Sialic Acid Binding Ig-Like Lectin 10; PRO940; SIGLEC10 Protein; Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7; SIGLEC-10; Sia
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P705202
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SIGLEC10; SIGLEC-Like Protein 2; Sialic Acid Binding Ig Like Lectin 10; SIGLEC-Like Gene 2; SLG2; MGC126774; SIGLEC-10; Sialic Acid Binding Ig-Like Lectin 10; PRO940; SIGLEC10 Protein; Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7; SIGLEC-10; Sialic Acid-Binding Ig-Like Lectin 10
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P78516
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SIGLEC10; SIGLEC-Like Protein 2; Sialic Acid Binding Ig Like Lectin 10; SIGLEC-Like Gene 2; SLG2; MGC126774; SIGLEC-10; Sialic Acid Binding Ig-Like Lectin 10; PRO940; SIGLEC10 Protein; Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7; SIGLEC-10; Sia
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P701083
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIGLEC10; SIGLEC-Like Protein 2; Sialic Acid Binding Ig Like Lectin 10; SIGLEC-Like Gene 2; SLG2; MGC126774; SIGLEC-10; Sialic Acid Binding Ig-Like Lectin 10; PRO940; SIGLEC10 Protein; Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7; SIGLEC-10; Sia
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P78205
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SIGLEC10; SIGLEC-Like Protein 2; Sialic Acid Binding Ig Like Lectin 10; SIGLEC-Like Gene 2; SLG2; MGC126774; SIGLEC-10; Sialic Acid Binding Ig-Like Lectin 10; PRO940; SIGLEC10 Protein; Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7; SIGLEC-10; Sia
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78206
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SIGLEC10; SIGLEC-Like Protein 2; Sialic Acid Binding Ig Like Lectin 10; SIGLEC-Like Gene 2; SLG2; MGC126774; SIGLEC-10; Sialic Acid Binding Ig-Like Lectin 10; PRO940; SIGLEC10 Protein; Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7; SIGLEC-10; Sia
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78514
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SIGLEC10; SIGLEC-Like Protein 2; Sialic Acid Binding Ig Like Lectin 10; SIGLEC-Like Gene 2; SLG2; MGC126774; SIGLEC-10; Sialic Acid Binding Ig-Like Lectin 10; PRO940; SIGLEC10 Protein; Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7; SIGLEC-10; Sia
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P992441

Research Areas:  

Cancer

PHST001 is a humanized anti-CD24 antibody. PHST001 binds cell-surface CD24, blocks CD24-Siglec10 interaction, and engages Fc receptors to promote macrophage-mediated tumor cell phagocytosis. PHST001 inhibits growth of breast cancer and ovarian cancer, and reduces metastatic lesions in mouse xenograft models. PHST001 can be used for the research of triple negative breast cancer, HER2+ breast cancer, metastatic tumors, and ovarian cancer .
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