Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Steap1
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Steap1" in MCE Product Catalog:
Cat. No.: HY-P990688
CAS No.: 2559056-68-5
Synonyms: AMG-509
Cat. No.: HY-P990673
Synonyms: DSTP-3086S Antibody; RG-7450 Antibody
Research Areas:
Research Areas:
PROTAC BRD4 Degrader linker conjugate is a linker-payload conjugate as well as a bifunctional degrader of BRD4 that binds to VHL, consisting of PROTAC and a linker. PROTAC BRD4 Degrader linker conjugate can be conjugated with STEAP1 and CLL1 antibodies to degrade BRD4 protein, with DC50 values of 0.86 nM and 7.6 nM, respectively. PROTAC BRD4 Degrader linker conjugate can be used in research related to prostate cancer and acute myeloid leukemia (BRD4 ligand: (HY-129939); VHL ligand: (HY-125845)) [1].\n
Cat. No.: HY-164995
CAS No.: 2417370-68-2
Research Areas:
L1BC8 (Compound 13a) is a drug-linker conjugate for ADC. L1BC8 is obtained by conjugating a BRD4 PROTAC degrader with a peptidomimetic protease-cleavable linker for the preparation of ADC, which can be conjugated to STEAP1 antibodies and CLL1 antibodies, respectively. L1BC8 can be used in research related to prostate cancer and acute myeloid leukemia [1].
Cat. No.: HY-RS13905
Target:
Research Areas:
STEAP1 Human Pre-designed siRNA Set A contains three designed siRNAs for STEAP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16998
Target:
Research Areas:
Steap1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Steap1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23441
Target:
Research Areas:
Steap1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Steap1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13906
Target:
Research Areas:
STEAP1B Human Pre-designed siRNA Set A contains three designed siRNAs for STEAP1B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P704159
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Steap1; Six-Transmembrane Epithelial Antigen Of Prostate 1; Prev. Steap; Steap1 Protein; PRSS24; Six Transmembrane Epithelial Antigen Of The Prostate; Six Transmembrane Epithelial Antigen Of The Prostate 1; Metalloreductase Steap1; Steap Family Member 1; Steap1 Metalloreductase
Species:
Human
Source:
HEK293
Cat. No.: HY-P702448
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Steap1; Six-Transmembrane Epithelial Antigen Of Prostate 1; Prev. Steap; Steap1 Protein; PRSS24; Six Transmembrane Epithelial Antigen Of The Prostate; Six Transmembrane Epithelial Antigen Of The Prostate 1; Metalloreductase Steap1; Steap Family Member 1;
Species:
Mouse
Source:
E. coli Cell-free
Cat. No.: HY-P702449
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Steap1; Six-Transmembrane Epithelial Antigen Of Prostate 1; Prev. Steap; Steap1 Protein; PRSS24; Six Transmembrane Epithelial Antigen Of The Prostate; Six Transmembrane Epithelial Antigen Of The Prostate 1; Metalloreductase Steap1; Steap Family Member 1;
Species:
Rat
Source:
E. coli Cell-free
Cat. No.: HY-P99528
CAS No.: 1471985-92-8
Synonyms: DSTP 3086S; RG 7450; MSTP2109A
Research Areas:
Vandortuzumab vedotin (DSTP 3086S) is an antibody-drug conjugate (ADC) targeting STEAP1. Vandortuzumab vedotin binds to STEAP1 and triggers internalization, mediating the intracellular release of MMAE, which inhibits microtubule polymerization, thereby inhibiting cell division and inducing cell death. Vandortuzumab vedotin shows antitumor activity in prostate cancer xenograft tumors. Vandortuzumab vedotin can be used in research on metastatic castration-resistant prostate cancer and prostate cancer [1] .
Cat. No.: HY-P9S0145
Target:
Research Areas:
ABBV-969 Antibody is an IgG1 antibody engineered to simultaneously bind PSMA and STEAP1. ABBV-969 Antibody can serve as an ADC Antibody and be conjugated with a topoisomerase I inhibitor and a Linker to form the ADC molecule ABBV-969. ABBV-969 can be used in research on metastatic castration-resistant prostate cancer [1] .
Cat. No.: HY-188284A
Target:
Research Areas:
ADC Control of ABBV-969 serves as an isotype control for the ABBV-969 antibody (HY-P9S0145). The ABBV-969 antibody, an IgG1 antibody capable of binding to both PSMA and STEAP1, is used in the synthesis of the antibody-drug conjugate (ADC) ABBV-969. ADC Control of ABBV-969 can be utilized in research concerning metastatic castration-resistant prostate cancer [1].
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
