1471985-92-8
Chemical Structure
Vandortuzumab vedotin
Synonym(s): DSTP 3086S; RG 7450; MSTP2109A
- CAS No.: 1471985-92-8
- Formula:N/A
- Molecular Weight:N/A
IUPAC Name: 3-bromo-2-(methylamino)phenol
SMILES: [Vandortuzumab vedotin]
Biological Activity: Vandortuzumab vedotin (DSTP 3086S; RG 7450) is a STEAP1-targeted antibody-drug conjugate (ADC). Vandortuzumab vedotin binds specifically to STEAP1, triggers internalization of the conjugate complex, mediates intracellular release of monomethyl auristatin E, inhibits cell division, and induces cell death. Vandortuzumab vedotin exhibits antitumor activity in preclinical prostate cancer xenografts. Vandortuzumab vedotin can be used for the research of metastatic castration-resistant prostate cancer[1].
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Vandortuzumab vedotin | 99.52% | Vandortuzumab vedotin (DSTP 3086S; RG 7450) is a STEAP1-targeted antibody-drug conjugate (ADC). Vandortuzumab vedotin binds specifically to STEAP1, triggers internalization of the conjugate complex, mediates intracellular release of monomethyl auristatin E, inhibits cell division, and induces cell death. Vandortuzumab vedotin exhibits antitumor activity in preclinical prostate cancer xenografts. Vandortuzumab vedotin can be used for the research of metastatic castration-resistant prostate cancer. | ||||||||||||||||||||
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Keywords
