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Results for "

Sulforaphane

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (7) Bacterial (2) Bcl-2 Family (2) Caspase (3) Drug Metabolite (5) Endogenous Metabolite (4) HDAC (3) Isotope-Labeled Compounds (1) JNK (1) Keap1-Nrf2 (2) MDM-2/p53 (1) NF-κB (1) Reactive Oxygen Species (ROS) (7) Reference Standards (3)
By Research Areas:	Cancer (14) Infection (2) Inflammation/Immunology (5)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-13755

*Sulforaphane* Maximum Cited Publications 69 Publications Verification	HDAC Keap1-Nrf2 Apoptosis Bcl-2 Family Caspase Reactive Oxygen Species (ROS)	Inflammation/Immunology Cancer
Sulforaphane is an orally active inducer of the Keap1/Nrf2/ARE pathway. Sulforaphane promotes the transcription of tumor-suppressing proteins and effectively inhibits the activity of HDACs. Through the activation of the Keap1/Nrf2/ARE pathway and further induction of HO-1 expression, Sulforaphane protects the heart. Sulforaphane suppresses high glucose-induced pancreatic cancer through AMPK-dependent signal transmission. Sulforaphane exhibits both anticancer and anti-inflammatory properties .

HY-N4068

Glucoraphanin 5+ Cited Publications	Reactive Oxygen Species (ROS) Endogenous Metabolite	Cancer
Glucoraphanin, a natural glucosinolate found in cruciferous vegetable, is a stable precursor of the Nrf2 inducer sulforaphane, which possesses antioxidant, anti-inflammatory, and anti-carcinogenic effects.

HY-13755A

(R)-Sulforaphane 2 Publications Verification L-Sulforaphane	Keap1-Nrf2 Bcl-2 Family Caspase Reactive Oxygen Species (ROS) NF-κB	Inflammation/Immunology Cancer
(R)-Sulforaphane (L-Sulforaphane) is a orally active, potent inducer of the Keap1/Nrf2/ARE pathway, exhibiting antioxidant and anticancer activities. (R)-Sulforaphane primarily functions by upregulating phase II detoxifying enzymes in cells, aiding in the removal of carcinogens and combating oxidative stress. (R)-Sulforaphane is capable of modulating gene expression, influencing various signaling pathways, including Nrf2, NF-κB, and AP-1. (R)-Sulforaphane can be used in studies of tumor biology, antioxidant defense mechanisms, as well as inflammation and immune responses .

HY-132242

*DL-Sulforaphane* N-acetyl-L-cysteine** SFN-NAC	HDAC Apoptosis Drug Metabolite	Cancer
DL-Sulforaphane N-acetyl-L-cysteine (SFN-NAC) is an orally active HDAC inhibitor and metabolite of sulforaphane (HY-13755) with longer half-life and better blood-brain barrier permeability. DL-Sulforaphane N-acetyl-L-cysteine activates autophagy-mediated downregulation of α-tubulin expression through the ERK pathway and can be used in cancer research .

HY-101413

Iberin 2 Publications Verification NSC 321801	Apoptosis Endogenous Metabolite Bacterial	Cancer
Iberin (NSC 321801), a sulfoxide analogue of sulforaphane, is a naturally occurring member of isothiocyanate family. Iberin inhibits cell survival with an IC₅₀ of 2.3 μM in HL60 cell. Iberin induces apoptosis.

HY-121204

Iberverin 3-Methylthiopropyl isothiocyanate	Apoptosis Reactive Oxygen Species (ROS)	Cancer
Iberverin (-Methylthiopropyl isothiocyanate) is a sulforaphane homolog. Iberverin has anticancer activity. Iberverin inhibits cell proliferation and migration. Iberverin induces mitochondrial-related apoptosis and intracellular reactive oxygen species .

HY-N4068R

Glucoraphanin (Standard)	Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite	Cancer
Glucoraphanin (Standard) is the analytical standard of Glucoraphanin. This product is intended for research and analytical applications. Glucoraphanin, a natural glucosinolate found in cruciferous vegetable, is a stable precursor of the Nrf2 inducer sulforaphane, which possesses antioxidant, anti-inflammatory, and anti-carcinogenic effects.

HY-W701218

Sulforaphane-d8	Reactive Oxygen Species (ROS)	Cancer
Sulforaphane-d₈ is the deuterium labeled Sulforaphane (HY-13755). Sulforaphane is an orally active inducer of the Keap1/Nrf2/ARE pathway. Sulforaphane promotes the transcription of tumor-suppressing proteins and effectively inhibits the activity of HDACs. Through the activation of the Keap1/Nrf2/ARE pathway and further induction of HO-1 expression, Sulforaphane protects the heart. Sulforaphane suppresses high glucose-induced pancreatic cancer through AMPK-dependent signal transmission. Sulforaphane exhibits both anticancer and anti-inflammatory properties .

HY-116794

SF5 2,2-Diphenylethyl isothiocyanate	Apoptosis JNK MDM-2/p53 Caspase	Cancer
SF5 (2,2-Diphenylethyl isothiocyanate) is a sulforaphane analog. SF5 inhibits apoptosis by the JNK-p53-caspase pathway. SF5 can be used as a new renal protective agent for drug-resistant acute renal disease .

HY-121076

Berteroin	Bacterial	Infection Inflammation/Immunology Cancer
Berteroin, a naturally occurring Sulforaphane analog, ia an antimetastatic agent. Berteroin has anti-inflammatory, antitumor and bactericidal effects .

HY-N10346

Gluconapin potassium 3-Butenyl glucosinolate potassium	Endogenous Metabolite	Infection Cancer
Gluconapin (3-Butenyl glucosinolate) potassium is an orally active aliphatic glucosinolate and also a flavor modifier. Gluconapin potassium inhibits the elevation of plasma triglyceride levels in mice. Gluconapin potassium also exhibits certain antibacterial activity .

HY-W588248

*DL-Sulforaphane* glutathione** DL-SFN-GSH	Drug Metabolite	Inflammation/Immunology
DL-Sulforaphane glutathione (DL-SFN-GSH) is a metabolite of Sulforaphane (HY-13755) in rat plasma .

HY-W710753

*D,L-Sulforaphane* glutathione-d5** DL-SFN-GSH-d₅	Isotope-Labeled Compounds Drug Metabolite	Inflammation/Immunology
D,L-Sulforaphane glutathione-d₅ (DL-SFN-GSH-d₅) is deuterium labeled DL-Sulforaphane glutathione. DL-Sulforaphane glutathione (DL-SFN-GSH) is a metabolite of Sulforaphane (HY-13755) in rat plasma .

HY-132242R

*DL-Sulforaphane* N-acetyl-L-cysteine (Standard)** SFN-NAC (Standard)	Reference Standards HDAC Apoptosis Drug Metabolite	Cancer
Pipemidic acid (trihydrate) (Standard) is the analytical standard of Pipemidic acid (trihydrate). This product is intended for research and analytical applications. Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid trihydrate inhibits DNA gyrase. Pipemidic acid trihydrate is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid trihydrate can be used for the research of intestinal, urinary, and biliary tract infections .

HY-121204R

Iberverin (Standard) 3-Methylthiopropyl isothiocyanate (Standard)	Reference Standards Apoptosis Reactive Oxygen Species (ROS)	Cancer
Iberverin (Standard) is the analytical standard of Iberverin. This product is intended for research and analytical applications. Iberverin (-Methylthiopropyl isothiocyanate) is a sulforaphane homolog. Iberverin has anticancer activity. Iberverin inhibits cell proliferation and migration. Iberverin induces mitochondrial-related apoptosis and intracellular reactive oxygen species[1].

HY-W588247

S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine SF-cysteine	Drug Metabolite	Cancer
S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine (SF-cysteine), a metabolite of Sulforaphane (HY-13755), can enhance the survival rate of Nalm-6 cells .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-13755

*Sulforaphane* Maximum Cited Publications 69 Publications Verification	Natural Products other families Classification of Application Fields Plants Inflammation/Immunology Disease Research Fields Source Classification	HDAC Keap1-Nrf2 Apoptosis Bcl-2 Family Caspase Reactive Oxygen Species (ROS)
Sulforaphane is an orally active inducer of the Keap1/Nrf2/ARE pathway. Sulforaphane promotes the transcription of tumor-suppressing proteins and effectively inhibits the activity of HDACs. Through the activation of the Keap1/Nrf2/ARE pathway and further induction of HO-1 expression, Sulforaphane protects the heart. Sulforaphane suppresses high glucose-induced pancreatic cancer through AMPK-dependent signal transmission. Sulforaphane exhibits both anticancer and anti-inflammatory properties .

HY-N4068

Glucoraphanin 5+ Cited Publications	Cruciferous vegetables Classification of Application Fields Other Alkaloids Glucosinolates Plants Brassicaceae Disease Research Fields Source Classification Cancer	Reactive Oxygen Species (ROS) Endogenous Metabolite
Glucoraphanin, a natural glucosinolate found in cruciferous vegetable, is a stable precursor of the Nrf2 inducer sulforaphane, which possesses antioxidant, anti-inflammatory, and anti-carcinogenic effects.

HY-13755A

(R)-Sulforaphane 2 Publications Verification L-Sulforaphane	Natural Products other families Classification of Application Fields Plants Disease Research Fields Source Classification Cancer	Keap1-Nrf2 Bcl-2 Family Caspase Reactive Oxygen Species (ROS) NF-κB
(R)-Sulforaphane (L-Sulforaphane) is a orally active, potent inducer of the Keap1/Nrf2/ARE pathway, exhibiting antioxidant and anticancer activities. (R)-Sulforaphane primarily functions by upregulating phase II detoxifying enzymes in cells, aiding in the removal of carcinogens and combating oxidative stress. (R)-Sulforaphane is capable of modulating gene expression, influencing various signaling pathways, including Nrf2, NF-κB, and AP-1. (R)-Sulforaphane can be used in studies of tumor biology, antioxidant defense mechanisms, as well as inflammation and immune responses .

HY-101413

Iberin 2 Publications Verification NSC 321801	Natural Products other families Classification of Application Fields Plants Endogenous metabolite Disease Research Fields Source Classification Cancer	Apoptosis Endogenous Metabolite Bacterial
Iberin (NSC 321801), a sulfoxide analogue of sulforaphane, is a naturally occurring member of isothiocyanate family. Iberin inhibits cell survival with an IC₅₀ of 2.3 μM in HL60 cell. Iberin induces apoptosis.

HY-121204

Iberverin 3-Methylthiopropyl isothiocyanate	Natural Products Cruciferous vegetables Classification of Application Fields Plants Brassicaceae Disease Research Fields Source Classification Cancer	Apoptosis Reactive Oxygen Species (ROS)
Iberverin (-Methylthiopropyl isothiocyanate) is a sulforaphane homolog. Iberverin has anticancer activity. Iberverin inhibits cell proliferation and migration. Iberverin induces mitochondrial-related apoptosis and intracellular reactive oxygen species .

HY-N4068R

Glucoraphanin (Standard)	Structural Classification Cruciferous vegetables Other Alkaloids Glucosinolates Plants Brassicaceae Source Classification	Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite
Glucoraphanin (Standard) is the analytical standard of Glucoraphanin. This product is intended for research and analytical applications. Glucoraphanin, a natural glucosinolate found in cruciferous vegetable, is a stable precursor of the Nrf2 inducer sulforaphane, which possesses antioxidant, anti-inflammatory, and anti-carcinogenic effects.

HY-N10346

Gluconapin potassium 3-Butenyl glucosinolate potassium	Structural Classification Brassica rapa L. Classification of Application Fields Ketones, Aldehydes, Acids Glucosinolates Plants Brassicaceae Disease Research Fields Source Classification Cancer	Endogenous Metabolite
Gluconapin (3-Butenyl glucosinolate) potassium is an orally active aliphatic glucosinolate and also a flavor modifier. Gluconapin potassium inhibits the elevation of plasma triglyceride levels in mice. Gluconapin potassium also exhibits certain antibacterial activity .

HY-121204R

Iberverin (Standard) 3-Methylthiopropyl isothiocyanate (Standard)	Structural Classification Natural Products Cruciferous vegetables Plants Brassicaceae Source Classification	Reference Standards Apoptosis Reactive Oxygen Species (ROS)
Iberverin (Standard) is the analytical standard of Iberverin. This product is intended for research and analytical applications. Iberverin (-Methylthiopropyl isothiocyanate) is a sulforaphane homolog. Iberverin has anticancer activity. Iberverin inhibits cell proliferation and migration. Iberverin induces mitochondrial-related apoptosis and intracellular reactive oxygen species[1].

Cat. No.	Product Name	Chemical Structure

HY-W701218

Sulforaphane-d8
Sulforaphane-d₈ is the deuterium labeled Sulforaphane (HY-13755). Sulforaphane is an orally active inducer of the Keap1/Nrf2/ARE pathway. Sulforaphane promotes the transcription of tumor-suppressing proteins and effectively inhibits the activity of HDACs. Through the activation of the Keap1/Nrf2/ARE pathway and further induction of HO-1 expression, Sulforaphane protects the heart. Sulforaphane suppresses high glucose-induced pancreatic cancer through AMPK-dependent signal transmission. Sulforaphane exhibits both anticancer and anti-inflammatory properties .

Sulforaphane-d8

Sulforaphane-d₈ is the deuterium labeled Sulforaphane (HY-13755). Sulforaphane is an orally active inducer of the Keap1/Nrf2/ARE pathway. Sulforaphane promotes the transcription of tumor-suppressing proteins and effectively inhibits the activity of HDACs. Through the activation of the Keap1/Nrf2/ARE pathway and further induction of HO-1 expression, Sulforaphane protects the heart. Sulforaphane suppresses high glucose-induced pancreatic cancer through AMPK-dependent signal transmission. Sulforaphane exhibits both anticancer and anti-inflammatory properties .

HY-W710753

*D,L-Sulforaphane* glutathione-d5**
D,L-Sulforaphane glutathione-d₅ (DL-SFN-GSH-d₅) is deuterium labeled DL-Sulforaphane glutathione. DL-Sulforaphane glutathione (DL-SFN-GSH) is a metabolite of Sulforaphane (HY-13755) in rat plasma .

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Sulforaphane

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products