26 Results for "

TREM1

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "TREM1" in MCE Product Catalog:

8
8 Publications Verification
Cat. No.: HY-P3211
CAS No.: 2014384-91-7
Synonyms: LR12
Nangibotide (LR12) is a synthetic peptide and TREM-1 receptor inhibitor. Nangibotide inhibits NF-κB and NLRP3 inflammasome activation and reduces the release of pro-inflammatory factors (such as IL-1β, IL-8). Nangibotide inhibits Apoptosis. Nangibotide reduces excessive inflammatory responses and protects tissues (liver, lung) from damage. Nangibotide can be used in the researches for myocardial ischemia-reperfusion injury, septic shock, acute lung injury, osteoarthritis, and acute liver failure [1] .
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8
8 Publications Verification
Cat. No.: HY-P3211A
Synonyms: LR12 TFA
Nangibotide TFA (LR12 TFA) is a synthetic peptide and TREM-1 receptor inhibitor. Nangibotide TFA inhibits NF-κB and NLRP3 inflammasome activation and reduces the release of pro-inflammatory factors (such as IL-1β, IL-8). Nangibotide TFA inhibits Apoptosis. Nangibotide TFA reduces excessive inflammatory responses and protects tissues (liver, lung) from damage. Nangibotide TFA can be used in the researches for myocardial ischemia-reperfusion injury, septic shock, acute lung injury, osteoarthritis, and acute liver failure [1] .
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4
4 Cited Publications
Cat. No.: HY-157122
CAS No.: 2765319-65-9
Purity:  99.68%
VJDT is a TREM1 inhibitor that can effectively block TREM1 signaling. VJDT inhibits tumor cell proliferation and migration and induces cell cycle arrest. VJDT has immunomodulatory and antitumor activities, and can be used for the research of tumors such as melanoma [1].
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3
3 Cited Publications
Cat. No.: HY-P3400
CAS No.: 887255-16-5
Synonyms: LQVTDSGLYRCVIYHPP
Target:  

Peptides

Research Areas:  

Neurological Disease

LP17 (LQVTDSGLYRCVIYHPP) is a BBB-penetrable triggering receptor expressed on myeloid cells (TREM-1) inhibitory peptide. LP17 substantially alleviates ischemia-induced infarction and neuronal injury. LP17 can get access into brain and block TREM-1 [1].
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3
3 Cited Publications
Cat. No.: HY-P3400A
Synonyms: LQVTDSGLYRCVIYHPP TFA
Target:  

Peptides

Research Areas:  

Neurological Disease

LP17 (LQVTDSGLYRCVIYHPP) TFA is a BBB-penetrable triggering receptor expressed on myeloid cells (TREM-1) inhibitory peptide. LP17 TFA substantially alleviates ischemia-induced infarction and neuronal injury. LP17 TFA can get access into brain and block TREM-1 [1].
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1
1 Cited Publications
Cat. No.: HY-P10086
CAS No.: 1289375-12-7
Synonyms: Human TREM-1(213-221)
TREM-1 inhibitory peptide GF9 (Human TREM-1 (213-221)) is a TREM-1 inhibitor. TREM-1 inhibitory peptide GF9 blocks the TREM-1 signaling pathway via a ligand-independent mechanism, spontaneously inserts into the cell membrane to dissociate TREM-1 from DAP-12, and functions through the Signaling Chain Homooligomerization (SCHOOL) model. TREM-1 inhibitory peptide GF9 reduces the levels of TNFα, IL-1β, IL-6, and M-CSF. TREM-1 inhibitory peptide GF9 inhibits tumor growth, prolongs the survival of mice with pancreatic cancer models, ameliorates collagen-induced arthritis, and exerts protective effects on bone and cartilage simultaneously. TREM-1 inhibitory peptide GF9 can be used in research related to arthritis, pancreatic cancer, retinopathy, alcoholic liver disease, and liver cancer [1] .
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1
1 Cited Publications
Cat. No.: HY-P5521
CAS No.: 3033299-76-9
Target:  

Peptides

Research Areas:  

Cardiovascular Disease

mLR12 is a Trem1 inhibitory peptide. mLR12 decreases aortic rupture rate in BAPN-induced Thoracic aortic aneurysm and dissection (TAAD) mice model [1].
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Cat. No.: HY-P10089
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

TREM-1 inhibitory peptide M3 is a ligand-dependent TREM-1 antagonist. TREM-1 inhibitory peptide M3 can inhibit systemic and pulmonary pro-inflammatory cytokine and chemokine production and attenuate acute lung injury [1].
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Cat. No.: HY-174369
Target:  

TREM receptor Syk

Research Areas:  

Neurological Disease

TREM2 agonist-3 (Compound 4i) is a TREM2 agonist with a KD value of 19.0 µM. The KD value of TREM2 agonist-3 for TREM1 is 39.8 µM. TREM2 agonist-3 induces an increase in phosphorylated SYK levels. TREM2 agonist-3 can be used in the research of neurodegenerative diseases and other diseases associated with TREM2 dysfunction [1].
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Cat. No.: HY-P11077
CAS No.: 1256099-50-9
Synonyms: TLT-1 (94-110)
Target:  

TREM receptor

Research Areas:  

Inflammation/Immunology

LR-17 (TLT-1 (94-110)), a 17-aa peptide, is a TREM-1 inhibitor. LR-17 shows anti-inflammatory effects that can reduce the secretion of pro-inflammatory cytokines induced by Lipopolysaccharides (HY-D1056) (LPS). LR-17 can be used for the study of sepsis [1].
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Cat. No.: HY-P10938
CAS No.: 887973-05-9
Target:  

TREM receptor

Research Areas:  

Inflammation/Immunology Cancer

LP17 (human) is a TREM1 antagonist peptide with anti-inflammatory and anti-cancer effects [1].
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Cat. No.: HY-P10087
CAS No.: 1292755-24-8
Synonyms: Mouse TREM-1(213–221), GF9
Target:  

Peptides

Research Areas:  

Inflammation/Immunology Cancer

Mouse TREM-1 SCHOOL peptide (Mouse TREM-1(213-221), GF9) targets the interaction between TREM-1 and its signaling partner DAP-12, specifically silencing the TREM-1 signaling pathway, regulate the production of TREM-1-mediated pro-inflammatory cytokines in vivo and in vitro. Mouse TREM-1 SCHOOL peptide has anti-tumor effects. Mouse TREM-1 SCHOOL peptide can reduce the formation of vitreoretinal neovascularization [1] .
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Cat. No.: HY-P990650

Target:  

TREM receptor

Research Areas:  

Cancer

PY159 is a humanized antibody targeting TREM1/CD354. PY159 reprograms immunosuppressive intratumoral myeloid cells towards an inflammatory, anti-tumor phenotype, promotes anti-tumor immune responses, upregulates monocyte activation markers, and induces proinflammatory cytokines. PY159 can be used for the research of platinum-resistant ovarian cancer, advanced solid tumors, and advanced refractory solid tumors [1] .
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Cat. No.: HY-RS16560
Research Areas:  

Others

Trem1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Trem1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS15002
Research Areas:  

Others

TREM1 Human Pre-designed siRNA Set A contains three designed siRNAs for TREM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P10088
Target:  

TREM receptor

Research Areas:  

Inflammation/Immunology Cancer

Mouse TREM-1 SCHOOL peptide, control is a negative control of Mouse TREM-1 SCHOOL peptide [1].
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Cat. No.: HY-RS22992
Research Areas:  

Others

Trem1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Trem1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P992331

Target:  

TREM receptor

Research Areas:  

Inflammation/Immunology

CEL383 is a human monoclonal antibody targeting TREM1. CEL383 blocks the TREM1 signaling pathway, thereby alleviating inflammation and reducing the levels of inflammatory mediators. CEL383 can be used in research related to inflammatory bowel disease [1] .
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Cat. No.: HY-P70716
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Triggering receptor expressed on myeloid cells 1; TREM-1; CD354; TREM1
Species:  
Source:  
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Cat. No.: HY-P77860
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD354; TREM-1
Species:  
Source:  
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