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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
TSSK
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "TSSK" in MCE Product Catalog:
1
1 Cited Publications
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ALK inhibitor 1 (compound 17) is a potent pyrimidin ALK inhibitor. ALK inhibitor 1 is a potent inhibitor of testis-specific serine/threonine kinase 2 (TSSK2; IC50=31 nM) and focal adhesion kinase (FAK; IC50=2 nM) .
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ALK inhibitor 2 (compound 18) is a potent pyrimidin ALK inhibitor. ALK inhibitor 2 is a potent inhibitor of testis-specific serine/threonine kinase 2 (TSSK2; IC50=37 nM) and focal adhesion kinase (FAK; IC50=5 nM) .
Cat. No.: HY-172545
CAS No.: 1202764-07-5
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AMG28 is an ATP-competitive inhibitor targeting TTBK1 and TTBK2, with IC50 values of 805 nM and 988 nM, respectively. AMG28 inhibits the phosphorylation of tau protein at the Ser422 site .
Cat. No.: HY-RS15188
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TSSK2 Human Pre-designed siRNA Set A contains three designed siRNAs for TSSK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS15189
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TSSK6 Human Pre-designed siRNA Set A contains three designed siRNAs for TSSK6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16379
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TSSK4 Human Pre-designed siRNA Set A contains three designed siRNAs for TSSK4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20504
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Tssk4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tssk4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS21070
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Tssk3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tssk3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS29400
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Tssk6 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tssk6 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-184429
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TSSK1 ligand-1 (Compound 9) is a TSSK1 ligand that can be used for the synthesis of PROTACs, such as PROTAC TSSK1 Degrader-1 (HY-184428) .
Cat. No.: HY-184464
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PROTAC TSSK1 Degrader-2 is a cereblon-recruiting PROTAC degrader targeting TSSK1, with a DC50 of 10.8 nM and an IC50 of 56.8 nM against TSSK1. PROTAC TSSK1 Degrader-2 recruits the cereblon E3 ubiquitin ligase to induce proteasomal degradation of TSSK1. PROTAC TSSK1 Degrader-2 reduces the motility and in vitro fertilization capacity of mouse sperm. PROTAC TSSK1 Degrader-2 undergoes metabolic N-dealkylation and exhibits high efflux. PROTAC TSSK1 Degrader-2 can be used in studies related to male fertility .
Cat. No.: HY-184428
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PROTAC TSSK1 Degrader-1 is a TSSK1 PROTAC degrader with a DC50 of 10.8 nM and an IC50 of 56.8 nM. PROTAC TSSK1 Degrader-1 reduces sperm motility and impairs in vitro fertilization capacity. PROTAC TSSK1 Degrader-1 undergoes metabolic N-dealkylation and exhibits high efflux properties. PROTAC TSSK1 Degrader-1 is applicable to studies related to male fertility .
Cat. No.: HY-RS16394
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TSSK3 Human Pre-designed siRNA Set A contains three designed siRNAs for TSSK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17426
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Tssk2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tssk2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22886
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Tssk6 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tssk6 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23881
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Tssk2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tssk2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27012
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Tssk4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tssk4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27587
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Tssk3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tssk3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P701652
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TSSK4; Testis-specific serine/threonine-protein kinase 4; TSK-4; TSSK-4; Testis-specific kinase 4; Serine/threonine-protein kinase 22E
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Cat. No.: HY-P701651
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TSSK4; Testis-specific serine/threonine-protein kinase 4; TSK-4; TSSK-4; Testis-specific kinase 4; Serine/threonine-protein kinase 22E
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
