4 Results for "

Tenuifolin

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Tenuifolin" in MCE Product Catalog:

2
Onjisaponin B
Onjisaponin B
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2 Cited Publications
Cat. No.: HY-N2099
CAS No.: 35906-36-6
Synonyms: Senegin III
Category:  

Triterpenes Neurological Disease Terpenoids Polygalaceae Plants Disease Research Fields Polygala tenuifolia Willd.

Target:  

Autophagy Amyloid-β Caspase NF-κB Apoptosis

Onjisaponin B is an orally active natural product derived from Polygala tenuifolia. Onjisaponin B inhibits NF-κB p65. Onjisaponin B enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin. Onjisaponin B reduces β-amyloid (Aβ) production. Onjisaponin B reduces radiation-induced cell apoptosis. Onjisaponin B has anti-oxidant and anti-inflammatory activities. Onjisaponin B can be used for neurological disease and radiation injury study, and its metabolite tenuifolin (TF) can enter the brain through the BBB .
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Tenuifolin
Tenuifolin
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Cat. No.: HY-N0702
CAS No.: 20183-47-5
Category:  

Triterpenes Terpenoids Polygalaceae Plants Polygala tenuifolia Willd.

Target:  

Beta-secretase Cholinesterase (ChE)

Tenuifolin is effective and has a protective action. Tenuifolin inhibits β-secretase decreases Aβ protein secretion, suppresses Aβ25-35 secretion, and subsequently caspase-3 and caspase-9 become active. Tenuifolin's ability to lower AChE activity, increase at the same time, increase the ability of the upper glands, and improve the ability to read and remember. Research on tenuifolin's potential for use in urinary disease (AD).
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Tenuifolin (Standard)
Tenuifolin (Standard)
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Cat. No.: HY-N0702R
CAS No.: 20183-47-5
Category:  

Triterpenes Terpenoids Polygalaceae Plants Polygala tenuifolia Willd.

Target:  

Reference Standards Beta-secretase Cholinesterase (ChE)

Tenuifolin (Standard) is the analytical standard of Tenuifolin. This product is intended for research and analytical applications. Tenuifolin is effective and has a protective action. Tenuifolin inhibits β-secretase decreases Aβ protein secretion, suppresses Aβ25-35 secretion, and subsequently caspase-3 and caspase-9 become active. Tenuifolin's ability to lower AChE activity, increase at the same time, increase the ability of the upper glands, and improve the ability to read and remember. Research on tenuifolin's potential for use in urinary disease (AD) .
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(Z)-Onjisaponin B
(Z)-Onjisaponin B
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Cat. No.: HY-N2099A
CAS No.: 162681-53-0
Synonyms: (Z)-Senegin III
Category:  

Polygala senega L. Triterpenes Terpenoids Polygalaceae Plants Pentacyclic Triterpenoids

Target:  

Drug Derivative

(Z)-Onjisaponin B ((Z)-Senegin III) is a derivative of Onjisaponin B (HY-N2099). Onjisaponin B is an orally active natural product derived from Polygala tenuifolia. Onjisaponin B inhibits NF-κB p65. Onjisaponin B enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin. Onjisaponin B reduces β-amyloid (Aβ) production. Onjisaponin B reduces radiation-induced cell apoptosis. Onjisaponin B has anti-oxidant and anti-inflammatory activities. Onjisaponin B can be used for neurological disease and radiation injury study, and its metabolite tenuifolin (TF) can enter the brain through the BBB .
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