18 Results for "

Trpm1

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "Trpm1" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-B0151
CAS No.: 145-13-1
Synonyms: 3β-Hydroxy-5-pregnen-20-one
Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication [1] . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
loading...
    loading...
7
7 Publications Verification
Cat. No.: HY-B1739
CAS No.: 1247-64-9
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate
Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate can protect the brain from cannabis intoxication [1] . Pregnenolone monosulfate is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
loading...
    loading...
7
7 Publications Verification
Cat. No.: HY-101464
CAS No.: 19992-50-8
Purity:  ≥98.0%
ML329 is a micropthalmia-associated transcription factor (MITF) inhibitor, which inhibits TRPM-1 promoter activity with an IC50 of 1.2 μM.
loading...
    loading...
7
7 Publications Verification
Cat. No.: HY-110189
CAS No.: 1852-38-6
Purity:  99.96%
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate sodium
Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication [1] . Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-110220
CAS No.: 1031496-06-6
Purity:  99.94%
Target:  

TRP Channel

Research Areas:  

Neurological Disease

CIM0216, a synthetic TRPM3 ligand, acts as a potent and selective agonist of TRPM3. CIM0216 exhibits selectivity for TRPM3 over TRPM1, TRPM2 and TRPM4-8. CIM0216 acts in a TRPM3-dependent manner to induce pain and evoke neuropeptide release from sensory nerve terminals in vitro. CIM0216 is a powerful tool for studies of the physiological functions of TRPM3, and can be used for neurogenic inflammation research [1].
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-156483
CAS No.: 1164471-33-3
Purity:  99.76%
TT-012 is a MITF inhibitor with a human MITF IC50 of 13.1 nM and a human MITF Kd value of 15.5 nM. TT-012 reduces mRNA levels of MITF downstream genes linked to melanosome biogenesis, cell survival, and proliferation, and upregulates cell cycle-inhibiting genes. TT-012 can be used for the research of melanoma[1][2][3].
loading...
    loading...
Cat. No.: HY-B0151R
CAS No.: 145-13-1
Synonyms: 3β-Hydroxy-5-pregnen-20-one (Standard)
Pregnenolone (Standard) is the analytical standard of Pregnenolone. This product is intended for research and analytical applications. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication [1] . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
loading...
    loading...
Cat. No.: HY-RS15111
Research Areas:  

Others

TRPM1 Human Pre-designed siRNA Set A contains three designed siRNAs for TRPM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-B0151S2
CAS No.: 61574-54-7
Synonyms: 3β-Hydroxy-5-pregnen-20-one-d4-1
Pregnenolone-d4-1 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication [1] . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
loading...
    loading...
Cat. No.: HY-RS17998
Research Areas:  

Others

Trpm1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Trpm1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS24470
Research Areas:  

Others

Trpm1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Trpm1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-110189S1
CAS No.: 1485492-21-4
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate-d4 sodium
Pregnenolone monosulfate-d4 sodium is the deuterium labeled Pregnenolone monosulfate sodium (HY-110189) . Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication [1] . Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
loading...
    loading...
Cat. No.: HY-B0151S
Synonyms: 3β-Hydroxy-5-pregnen-20-one-d4
Pregnenolone-d4 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication [1] . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
loading...
    loading...
Cat. No.: HY-B0151S1
CAS No.: 2483824-26-4
Synonyms: 3β-Hydroxy-5-pregnen-20-one-13C2,d2
Pregnenolone- 13C2,d2 is the deuterium and 13C labeled Pregnenolone (HY-B0151). Pregnenolone is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels [1] .
loading...
    loading...
Cat. No.: HY-110189R
CAS No.: 1852-38-6
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate sodium (Standard)
Pregnenolone monosulfate (sodium) (Standard) is the analytical standard of Pregnenolone monosulfate (sodium). This product is intended for research and analytical applications. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication [1] . Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
loading...
    loading...
Cat. No.: HY-110189S
CAS No.: 2483824-22-0
Synonyms: 3β-Hydroxy-5-pregnen-20-one monosulfate sodium-13C2,d2
Pregnenolone monosulfate (sodium)- 13C2,d2 is the 13C- and deuterium labeled Pregnenolone monosulfate sodium. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium salt acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium salt can protect the brain from cannabis intoxication [1] . Pregnenolone monosulfate sodium salt is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
loading...
    loading...
Cat. No.: HY-101464R
CAS No.: 19992-50-8
Research Areas:  

Others

ML329 (Standard) is the analytical standard of ML329 (HY-101464). This product is intended for research and analytical applications. ML329 is a micropthalmia-associated transcription factor (MITF) inhibitor, which inhibits TRPM-1 promoter activity with an IC50 of 1.2 μM.
loading...
    loading...
Cat. No.: HY-B0151S3
Synonyms: 3β-Hydroxy-5-pregnen-20-one-d6
Pregnenolone-d6 (3β-Hydroxy-5-pregnen-20-one-d6) is the deuterium labeled Pregnenolone (HY-B0151) [1]. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication . Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
loading...
    loading...
  • 1