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Ursolic acid

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By Targets:	Apoptosis (1) Autophagy (2) Bacterial (1) Biochemical Assay Reagents (1) Drug Derivative (1) Endogenous Metabolite (3) Glycosidase (1) HIV (1) HSP (1) NF-κB (1) Parasite (1) Reference Standards (1) Reverse Transcriptase (1)
By Research Areas:	Cancer (6) Infection (3) Inflammation/Immunology (3) Metabolic Disease (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0140

Ursolic acid 15+ Cited Publications Prunol; Urson; Malol	Autophagy Endogenous Metabolite	Cancer
Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy.

HY-N1486

Ursonic acid 1 Publications Verification 3-KetoUrsolic acid	Apoptosis Endogenous Metabolite NF-κB	Inflammation/Immunology Cancer
Ursolic acid is a naturally occurring triterpenoid that has orally active. Ursolic acid induces the apoptosis of human cancer cells through multiple signaling pathways. Ursolic acid has anti-inflammatory and anticarcinogenic activity .

HY-N2815

Ursolic acid acetate AcetylUrsolic acid; 3-AcetylUrsolic acid	Parasite HSP	Infection Cancer
Ursolic acid acetate (Acetylursolic acid) is a triterpenoid compound and an inhibitor of Plasmodium falciparum heat shock protein 90 (PfHsp90) with a K_D of 8.16 μM. Ursolic acid acetate is cytotoxic to KB cells, with an IC₅₀ value of 8.4 μM. Ursolic acid acetate can be used in tumor and antimalarial research .

HY-N0140R

Ursolic acid (Standard) Prunol (Standard); Urson (Standard); Malol (Standard)	Reference Standards Autophagy Endogenous Metabolite	Cancer
Ursolic acid (Standard) is the analytical standard of Ursolic acid. This product is intended for research and analytical applications. Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy.

HY-N8896

Ursolic aldehyde	Others	Others
Ursolic aldehyde is a triterpenoid isolated from plants .

HY-N12161

*3-Acetyl-11-keto-ursolic* acid**	Others	Metabolic Disease
3-Acetyl-11-keto-ursolic acid (Compound 18) is a triterpenoid compound derived from Eriobotrya japonicaleaves. 3-Acetyl-11-keto-ursolic acid has 11B-hydroxysteroid dehydrogenase 1 (11b-HSD1) inhibitory activity. 3-Acetyl-11-keto-ursolic acid can be used for anti-diabetes research .

HY-N12014

Triptotriterpenic acid C	Others	Others
Triptotriterpenic acid C is a ursolic-type acid that can be isolated from total glycosides extracted from the root of Tripterygium wilfordii Hook.f. .

HY-N7623

Ursonic acid methyl ester	Drug Derivative	Cancer
Ursonic acid methyl ester is an esterified derivative of Ursolic acid (HY-N0140). Ursonic acid methyl ester shows growth inhibitory activity against four tumor cell lines, HL-60, BGC, Bel-7402 and Hela with ED₅₀ values of >100 µg/ml .

HY-N19933

*cis-3-O-Hydroxycinnamoyl-ursolic* acid**	Glycosidase	Others
cis-3-O-Hydroxycinnamoyl-ursolic acid is a cis-cinnamic acid ester derivative. cis-3-O-Hydroxycinnamoyl-ursolic acid exhibits no α-glucosidase inhibitory activity .

HY-N17718

Urushiol (15:3) 3-[8'(Z), 11'(Z), 14'-Pentadecatrienyl] catechol	HIV Reverse Transcriptase	Infection Cancer
Ursolic acid (15:3) (Compound 4) is a type of resiniferatoxin compound that can be found in the leaves of the tree Rhus verniciflua. Ursolic acid (15:3) exhibits moderate inhibitory activity against HIV-1 reverse transcriptase (b HIV-1 reverse transcriptase), with an IC₅₀ value of 55.36 μM. Ursolic acid (15:3) shows strong cytotoxicity against both PC-3 and MRC-5 cells. Ursolic acid (15:3) can be used in the research of anti-HIV-1 infection and prostate cancer .

HY-N18730

Ocimum sanctum extract	Bacterial	Infection Inflammation/Immunology
The main active ingredients of Ocimum sanctum extract include ursolic acid, eugenol, rosmarinic acid, flavonoids, and phenolic compounds, which endow it with adaptogenic, anti-inflammatory, antioxidant, and antibacterial effects.

HY-E71272

β-Amyrin 28-monooxygenase	Biochemical Assay Reagents	Others
β-Amyrin 28-monooxygenase (EC 1.14.13.201), found in plants, is involved in the biosynthesis of oleanane-type triterpenoids, such as ginsenoside Ro. The enzyme from Medicago trunculata (CYP716A12) can also convert α-amyrin and lupeol to ursolic acid and betulinic acid, respectively.

HY-N18744

Eclipta alba extract	Others	Inflammation/Immunology
Eclipta alba extract is a versatile plant extract derived from the whole plant of Wedelia candel. It is rich in various bioactive compounds, such as eclipta lactone, wedelia saponins, ursolic acid, oleanolic acid, luteolin, and apigenin. Eclipta alba extract is a potent hepatoprotective agent, helping to improve liver function and protect the liver from damage.

Ursolic acid 15+ Cited Publications Prunol; Urson; Malol	Triterpenes Structural Classification Classification of Application Fields Terpenoids Plants Actaea simplex (DC.) Wormsk. ex Fisch. & C. A. Mey. Endogenous metabolite Rhamnaceae Disease Research Fields Source Classification Cancer	Autophagy Endogenous Metabolite
Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy.

Ursonic acid 1 Publications Verification 3-KetoUrsolic acid	Triterpenes Classification of Application Fields Terpenoids Plants Actaea simplex (DC.) Wormsk. ex Fisch. & C. A. Mey. Rhamnaceae Endogenous metabolite Disease Research Fields Cancer Source Classification	Apoptosis Endogenous Metabolite NF-κB
Ursolic acid is a naturally occurring triterpenoid that has orally active. Ursolic acid induces the apoptosis of human cancer cells through multiple signaling pathways. Ursolic acid has anti-inflammatory and anticarcinogenic activity .

Ursolic acid acetate AcetylUrsolic acid; 3-AcetylUrsolic acid	Triterpenes other families Classification of Application Fields Terpenoids Plants Disease Research Fields Source Classification Cancer	Parasite HSP
Ursolic acid acetate (Acetylursolic acid) is a triterpenoid compound and an inhibitor of Plasmodium falciparum heat shock protein 90 (PfHsp90) with a K_D of 8.16 μM. Ursolic acid acetate is cytotoxic to KB cells, with an IC₅₀ value of 8.4 μM. Ursolic acid acetate can be used in tumor and antimalarial research .

Ursolic acid (Standard) Prunol (Standard); Urson (Standard); Malol (Standard)	Triterpenes Structural Classification Terpenoids Plants Actaea simplex (DC.) Wormsk. ex Fisch. & C. A. Mey. Endogenous metabolite Rhamnaceae Source Classification	Reference Standards Autophagy Endogenous Metabolite
Ursolic acid (Standard) is the analytical standard of Ursolic acid. This product is intended for research and analytical applications. Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy.

Ursolic aldehyde	Triterpenes Terpenoids Plants Bignoniaceae Campsis grandiflora (Thunb.) Schum. Source Classification	Others
Ursolic aldehyde is a triterpenoid isolated from plants .

*3-Acetyl-11-keto-ursolic* acid**	Ketones, Aldehydes, Acids Rosaceae Plants Eriobotrya japonica (Thunb.) Lindl. Source Classification	Others
3-Acetyl-11-keto-ursolic acid (Compound 18) is a triterpenoid compound derived from Eriobotrya japonicaleaves. 3-Acetyl-11-keto-ursolic acid has 11B-hydroxysteroid dehydrogenase 1 (11b-HSD1) inhibitory activity. 3-Acetyl-11-keto-ursolic acid can be used for anti-diabetes research .

Triptotriterpenic acid C	Ketones, Aldehydes, Acids Celastraceae Plants Tripterygium wilfordii Hook. f. Source Classification	Others
Triptotriterpenic acid C is a ursolic-type acid that can be isolated from total glycosides extracted from the root of Tripterygium wilfordii Hook.f. .

*cis-3-O-Hydroxycinnamoyl-ursolic* acid**	Triterpenes Structural Classification Mimusops elengi L. Terpenoids Plants Mimusops Source Classification	Glycosidase
cis-3-O-Hydroxycinnamoyl-ursolic acid is a cis-cinnamic acid ester derivative. cis-3-O-Hydroxycinnamoyl-ursolic acid exhibits no α-glucosidase inhibitory activity .

Urushiol (15:3) 3-[8'(Z), 11'(Z), 14'-Pentadecatrienyl] catechol	Structural Classification Phenols Polyphenols Plants Toxicodendron vernicifluum (Stokes) F. A. Barkl. Anacardiaceae Source Classification	HIV Reverse Transcriptase
Ursolic acid (15:3) (Compound 4) is a type of resiniferatoxin compound that can be found in the leaves of the tree Rhus verniciflua. Ursolic acid (15:3) exhibits moderate inhibitory activity against HIV-1 reverse transcriptase (b HIV-1 reverse transcriptase), with an IC₅₀ value of 55.36 μM. Ursolic acid (15:3) shows strong cytotoxicity against both PC-3 and MRC-5 cells. Ursolic acid (15:3) can be used in the research of anti-HIV-1 infection and prostate cancer .

Ocimum sanctum extract	Structural Classification Extract	Bacterial
The main active ingredients of Ocimum sanctum extract include ursolic acid, eugenol, rosmarinic acid, flavonoids, and phenolic compounds, which endow it with adaptogenic, anti-inflammatory, antioxidant, and antibacterial effects.

Eclipta alba extract	Structural Classification Extract	Others
Eclipta alba extract is a versatile plant extract derived from the whole plant of Wedelia candel. It is rich in various bioactive compounds, such as eclipta lactone, wedelia saponins, ursolic acid, oleanolic acid, luteolin, and apigenin. Eclipta alba extract is a potent hepatoprotective agent, helping to improve liver function and protect the liver from damage.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Ursolic acid

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