1 Result for "

YO2

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "YO2" in MCE Product Catalog:

Art. -Nr.: HY-183877
CAS. Nr.: 288254-44-4
Target:  

MDM-2/p53 Apoptosis

Forschungsgebiete:  

Inflammation/Immunology Cancer

YO-2 is a plasmin inhibitor and TP53 upregulator with anti-tumor and apoptosis-inducing activities. YO-2 upregulates the expression of TP53 and the tumor-suppressive miR-103/107, downregulates LRP1, and induces cellular DNA fragmentation and caspase cascade activation. YO-2 effectively blocks the growth of melanoma. YO-2 has been widely used in studies related to melanoma and colon cancer [2].
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