69 Results for "

amyloid β-protein

" in MedChemExpress (MCE) Product Catalog:
Products (69)

69 Results for "amyloid β-protein" in MCE Product Catalog:

23
23 Publications Verification
Cat. No.: HY-N0931
CAS No.: 1477949-42-0
Synonyms: CAY-10683
Santacruzamate A (CAY-10683, STA) is a potent and selective HDAC2 inhibitor with an IC50 of 119 pM. STA also exerts neuroprotective property against amyloid-β protein fragment 25–35. STA can be used for cancer and neurological disease research .
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6
6 Cited Publications
Cat. No.: HY-19369
CAS No.: 292632-98-5
Synonyms: L-685,458
Target:  

γ-secretase Apoptosis

Research Areas:  

Neurological Disease Cancer

L-685458 is a potent transition state analog (TSA) γ-secretase inhibitor (GSI). L-685458 inhibits amyloid β-protein precursor γ-secretase activity with IC50 of 17 nM, shows greater than 50-100-fold selectivity over other aspartyl proteases tested. L685458 inhibits γ-secretase-mediated cleavage of APP-C99 and Notch-100 with IC50s of 301.3 nM and 351.3 nM, respectively. L-685458 can be used for the research of alzheimer’s disease (AD) and cancers .
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1
1 Cited Publications
Cat. No.: HY-P3908
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

FITC-β-Ala-Amyloid β-Protein (1-42) ammonium is a FITC tagged Aβ1-42 peptide. Aβ1-42 plays a key role in the pathogenesis of Alzheimer’s disease .
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Cat. No.: HY-P5096
CAS No.: 1802087-77-9
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

FITC-β-Ala-Amyloid β-Protein (1-42) is a FITC tagged Aβ1-42 peptide. Aβ1-42 plays a key role in the pathogenesis of Alzheimer’s disease .
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Cat. No.: HY-P1466
CAS No.: 131580-10-4
Synonyms: amyloid β-protein (1-16)
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

β-Amyloid (1-16) is a β-Amyloid protein fragment involved in metal binding. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.
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Cat. No.: HY-P4882A
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

(Pyr3)-Amyloid β-Protein (3-42) TFA is the predominant amyloid β-peptide structure deposited in human brain of Alzheimer's disease and Down's syndrome patients. (Pyr3)-Amyloid β-Protein (3-42) TFA is suggested to accumulate in the brain and to trigger the formation of insoluble amyloid β-peptide deposits .
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Cat. No.: HY-124322
CAS No.: 1262857-73-7
Purity:  99.08%
NB-360 is a potent, brain penetrable and orally active β‐secretase 1/2 (BACE1/BACE2) dual inhibitor with IC50 values of 5 and 6 nM. NB-360 can inhibit amyloid-β protein accumulation. NB-360 can be used for the researches of inflammation and neurological disease, such as Alzheimer's disease .
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Cat. No.: HY-D1443
CAS No.: 291766-06-8
Synonyms: (trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene
BSB is a Congo red-derived fluorescent probe. BSB binds not only to extracellular amyloid β protein, but also many intracellular lesions composed of abnormal tau and synuclein proteins. BSB acts as a prototype imaging agent for Alzheimer's disease .
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Cat. No.: HY-77817
CAS No.: 1003-29-8
Synonyms: 2-Formylpyrrole
Pyrrole-2-carboxaldehyde (2-Formylpyrrole) is a heterocyclic organic compound that serves as a scaffold for the synthesis of various bioactive compounds .
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Cat. No.: HY-P10040
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

(Gln22)β-Amyloid (1-40) human is an amyloid beta protein (Aβ)-containing peptide used in Alzheimer's disease research .
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Cat. No.: HY-P1046
CAS No.: 183745-81-5
Synonyms: amyloid β-protein (1-15)
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

β-Amyloid (1-15) is a fragment of β-Amyloid peptide. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.
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Cat. No.: HY-P4882
CAS No.: 183449-57-2
Target:  

Amyloid-β Tau Protein

Research Areas:  

Neurological Disease

(Pyr3)-Amyloid β-Protein (3-42) is an N-terminally truncated pyroglutamylated β-amyloid peptide. (Pyr3)-Amyloid β-Protein (3-42) forms stable β-sheet structures across different pH values, co-oligomerizes with Aβ1-42 to form cytotoxic oligomers, induces tau-dependent cytotoxicity and neuronal loss, inhibits hippocampal LTP, and exhibits stronger protease resistance. (Pyr3)-Amyloid β-Protein (3-42) exists in the brain tissues of human Alzheimer's disease patients, correlates with the pathogenesis of Alzheimer's disease, and follows a unique, faster oligomerization pathway. (Pyr3)-Amyloid β-Protein (3-42) can be used in Alzheimer's disease-related research .
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Cat. No.: HY-P4788
CAS No.: 903883-22-7
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Acetyl-Amyloid β-Protein (1-6) amide is a hexapeptide that contains a potential copper(II) binding site. Acetyl-Amyloid β-Protein (1-6) amide can be used for research of Alzheimer's disease and related disorders .
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Cat. No.: HY-P3859
CAS No.: 1802086-21-0
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Cys-Gly-Lys-Arg-Amyloid β-Protein (1-42) is a peptide fragment of amyloid β-protein (Aβ). Cys-Gly-Lys-Arg-Amyloid β-Protein (1-42) can be used in research of Alzheimer's disease .
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Cat. No.: HY-P3780
CAS No.: 1802078-25-6
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Cys-Gly-Lys-Lys-Gly-Amyloid β-Protein (36-42) is the 36-42 fragment of Amyloid β-Protein. β-amyloid, a polypeptide made up of 36-43 amino acids, is the main component of amyloid plaques found in the brains of people with Alzheimer's disease. β-amyloid oligomers (Aβos) plays A key role in the progression of Alzheimer's disease (AD) by inducing neuronal damage and cognitive impairment .
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Cat. No.: HY-P4886A
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Amyloid β-Protein (3-42) TFA is a precursor of Pyr peptide. Pyroglutamic acid-modified Aβ (pEAβ) (3-42) is the core of the amyloid plaque in Alzheimer's disease. pEAβ (3-42) accelerates the aggregation of Aβ(1-42), while Aβ(1-42) significantly slows down the primary and secondary nucleation of pEAβ(3-42).
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Cat. No.: HY-P1468
CAS No.: 109770-29-8
Synonyms: amyloid β-protein (1-28)
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.
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Cat. No.: HY-N13742
CAS No.: 219565-74-9
Synonyms: Dihydrohonokiol
Dihydrohonokiol B (Dihydrohonokiol) is an anxiolytic agent. Dihydrohonokiol B can reduce the neurotoxicity induced by amyloid β protein by stimulating the GABAC receptor. Dihydrohonokiol B can be used in the research of neurodegenerative diseases such as Alzheimer's disease .
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Cat. No.: HY-P3846
CAS No.: 1802086-22-1
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

(Glu20)-Amyloid β-Protein (1-42) is a slower fibrillizing variant of amyloid β-protein (Aβ). The Glu20 mutation reduces the aggregation propensity of Aβ42 and prevents accumulation of the slowly fibrillizing peptide. Amyloid β-protein is the primary component of both vascular and parenchymal amyloid deposits in Alzheimer's disease .
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Cat. No.: HY-P4884
CAS No.: 285554-31-6
Target:  

Amyloid-β

Research Areas:  

Others

Amyloid β-Protein (1-46) is aAβ Fragment.
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