1. Neuronal Signaling
  2. Amyloid-β
  3. β-Amyloid 1-28

β-Amyloid 1-28 (Synonyms: Amyloid β-Protein (1-28))

Cat. No.: HY-P1468
Handling Instructions

β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

β-Amyloid 1-28 Chemical Structure

β-Amyloid 1-28 Chemical Structure

CAS No. : 109770-29-8

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Description

β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.

IC50 & Target

Amyloid-β[1]

In Vivo

β-Amyloid (1-28) fragment is considered as valid models to examine the contribution of the key histidine residues (His , His in mouse and His , His , His in human fragments) to the Ab–Cu2+ interaction[1]. Copper binds to β-Amyloid (1-28) at pH 7.4 with an affinity of Ka10 7 M-1[2].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

3262.51

Formula

C₁₄₅H₂₀₉N₄₁O₄₆

CAS No.

109770-29-8

Sequence

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys

Sequence Shortening

DAEFRHDSGYEVHHQKLVFFAEDVGSNK

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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β-Amyloid 1-28
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β-Amyloid 1-28

Cat. No.: HY-P1468