26 Results for "

antihyperlipidemic

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "antihyperlipidemic" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-B0388
CAS No.: 23288-49-5
Synonyms: DH-581
Probucol (DH-581) is an anti-hyperlipidemic agent. Probucol activates glutathione peroxidase. Probucol promotes low density lipoprotein (LDL) catabolism, inhibits ABCA1-dependent cholesterol efflux, and decreases HDL-C levels. Probucol also has anti-inflammatory, antioxidant and neuroprotective properties. Probucol can be used for researches on bone, cardiovascular, cancer, neurological, and metabolism-related diseases .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-14739
CAS No.: 856676-23-8
Purity:  99.86%
Synonyms: ABT-335
Target:  

PPAR COX

Research Areas:  

Cardiovascular Disease

Choline Fenofibrate (ABT-335), a choline salt of Fenofibric acid (HY-B0760), releases free Fenofibric acid in the gastrointestinal tract. Fenofibric acid is a PPAR activator with antihyperlipidemic effect .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-N7676
CAS No.: 535-96-6
Marein has the neuroprotective effect due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway. Marein improves insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. Marein is a HDAC inhibitor with an IC50 of 100 μM. Marein has beneficial antioxidative, antihypertensive, antihyperlipidemic and antidiabetic effects .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N4137
CAS No.: 13850-16-3
Tormentic acid, a triterpene isolated from Rosa rugosa, exerts anti-inflammatory, antihyperlipidemic, and anti-atherogenic properties .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N2555
CAS No.: 4291-60-5
Tilianin is an active flavonoid glycoside found in many medical plants, with potential anti-hypertensive, myocardial-protective, anti-diabetic, anti-hyperlipidemic, anti-inflammatory and antioxidant effects .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-122951
CAS No.: 560-66-7
Purity:  98.97%
Eburicoic acid protects the liver from CCl4-induced hepatic damage via antioxidant and anti-inflammatory mechanisms . And Eburicoic acid has antidiabetic and antihyperlipidemic effects .
loading...
    loading...
Cat. No.: HY-N2923
CAS No.: 1616-93-9
β-Amyrin acetate is a triterpenoid with potent anti-inflammatory, antifungal, anti-diabetic, anti-hyperlipidemic activities. β-Amyrin acetate can inhibit HMG-CoA reductase activity by locating in the hydrophobic binding cleft of HMG CoA reductase .
loading...
    loading...
Cat. No.: HY-117549
CAS No.: 133208-93-2
Purity:  99.48%
Synonyms: NO-1886
Target:  

Lipase

Research Areas:  

Cardiovascular Disease

Ibrolipim (NO-1886) is an orally active lipoprotein lipase (LPL)-promoting agent. Ibrolipim decreases plasma triglycerides, increases high-density lipoprotein cholesterol levels. Ibrolipim has renoprotective and hypolipidemic effects .
loading...
    loading...
Cat. No.: HY-75625
CAS No.: 2237-36-7
Synonyms: 4-Methoxysalicylic Acid
2-Hydroxy-4-methoxybenzoic acid is an orally active inhibitor of MCT-1 and MCT-4, as well as a plant biomarker. 2-Hydroxy-4-methoxybenzoic acid can be isolated from roots. 2-Hydroxy-4-methoxybenzoic acid induces Apoptosis and loss of mitochondrial membrane potential. 2-Hydroxy-4-methoxybenzoic acid exhibits anticancer activity against breast cancer. 2-Hydroxy-4-methoxybenzoic acid normalizes lactic acid levels. 2-Hydroxy-4-methoxybenzoic acid neutralizes viper venom and attenuates its lethal, hemorrhagic, coagulant and anticoagulant activities in male albino mice. 2-Hydroxy-4-methoxybenzoic acid possesses antihyperlipidemic, antidiabetic and hepatoprotective activities .
loading...
    loading...
Cat. No.: HY-B0388R
CAS No.: 23288-49-5
Synonyms: DH-581 (Standard)
Research Areas:  

Metabolic Disease

Probucol (Standard) is the analytical standard of Probucol. This product is intended for research and analytical applications. Probucol (DH-581) is an anti-hyperlipidemic agent by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.
loading...
    loading...
Cat. No.: HY-N8144
CAS No.: 95262-48-9
Niga-ichigoside F1, an orally active ursane triterpenoid, has antihyperlipidemic and antioxidant activities. Niga-ichigoside F1 can prevent high-fat diet (HFD)-induced hepatic steatosis .
loading...
    loading...
Cat. No.: HY-136059
CAS No.: 302781-98-2
Target:  

Keap1-Nrf2 Autophagy

Research Areas:  

Cardiovascular Disease Cancer

Desfluoro-ezetimibe is a desfluoro impurity of Ezetimibe. Ezetimibe is a potent, metabolically stable cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator .
loading...
    loading...
Cat. No.: HY-106580
CAS No.: 63394-05-8
Synonyms: ITA 104
Plafibride (ITA 104) is an orally active hypolipemic, platelet aggregation inhibitor .
loading...
    loading...
Cat. No.: HY-W011334
CAS No.: 2380-27-0
Methyl 12-oxooctadecanoate is a fatty acid that can be isolated from the pulp of Livistona decipiens (Palmae), which has anti-hyperlipidemic and anti-ulcer activities .
loading...
    loading...
Cat. No.: HY-156977
CAS No.: 55902-94-8
Target:  

PPAR

Research Areas:  

Cardiovascular Disease

Sitofibrate is a Clofibrate (HY-B0287) derivative. Sitofibrate is aperoxisome proliferator activated receptor-α (PPAR-α) agonist. Sitofibrate is an antihyperlipidemic agent .
loading...
    loading...
Cat. No.: HY-139134
CAS No.: 155730-92-0
S-2E is an orally active and noncompetitive HMG-CoA reductase and acetyl-CoA carboxylase inhibitor. S-2E has an anti-hyperlipidemic action. S-2E has the potential for familial hypercholesterolemia and mixed hyperlipidemia research .
loading...
    loading...
Cat. No.: HY-124477
CAS No.: 163391-76-2
Stachybotrylactam (17) is a phenylspirodrimane isolated from Stachybotrys chartarum with antihyperlipidemic activity. Stachybotrylactam also has antiviral activity .
loading...
    loading...
Cat. No.: HY-N9010
CAS No.: 1528745-88-1
Target:  

Others

Chartarlactam A is a novel compound with anti-hyperlipidemic activity. Chartarlactam A exhibits inhibitory potential in HepG2 cells .
loading...
    loading...
Cat. No.: HY-B0388S1
Synonyms: DH-581-d6
Probucol-d6 is deuterium labeled Probucol. Probucol (DH-581) is an anti-hyperlipidemic agent by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.
loading...
    loading...
Cat. No.: HY-B0388S
CAS No.: 1173019-29-8
Probucol- 13C3 is the 13C-labeled Probucol. Probucol (DH-581) is an anti-hyperlipidemic agent by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.
loading...
    loading...