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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
breakpoint
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "breakpoint" in MCE Product Catalog:
1
1 Cited Publications
Target:
GW779439X is a pyrazolopyridazine identified in an inhibitor of the S. aureus PASTA kinase Stk1. GW779439X potentiates the activity of β-lactam antibiotics against various MRSA and MSSA isolates, some even crossing the breakpoint from resistant to sensitive. GW779439X is an AURKA inhibitor and induces apoptosis by the caspases 3/7 pathway . MRSA:methicillin-resistant S. aureus; MSSA: methicillin-sensitive S. aureus
Referencia número: HY-154979
No. CAS: 2380421-60-1
Target:
Áreas de investigación:
Anti-hepatic fibrosis agent 2 (Compound 6k) is an orally active COL1A1 inhibitor. Anti-hepatic fibrosis agent 2 is an anti-fibrogenic agent targeting ewing sarcoma breakpoint region 1 (EWSR1) .
Referencia número: HY-150566
No. CAS: 1795736-60-5
BCR-ABL-IN-5 (compound II) is a Bcr-Abl kinase (Breakpoint cluster region-Abelson) inhibitor. BCR-ABL-IN-5 inhibits Bcr-Abl WT and Bcr-Abl T3151 with the IC50 value of 0.014 μM and 0.45 μM, respectively. BCR-ABL-IN-5 has some anti-proliferative activity against leukemic cells .
Referencia número: HY-P75896
Pureza: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: JTB; Protein JTB; Jumping Translocation breakpoint; Prostate Androgen-Regulated Gene; HJT; PAR Protein; PAR; HSPC222; Jumping Translocation breakpoint Protein; HJTB; Prostate Androgen-Regulated Protein
Species:
Human
Source:
HEK293
Referencia número: HY-103645R
No. CAS: 551919-98-3
GW779439X (Standard) is the analytical standard of GW779439X (HY-103645). This product is intended for research and analytical applications. GW779439X is a pyrazolopyridazine identified in an inhibitor of the S. aureus PASTA kinase Stk1. GW779439X potentiates the activity of β-lactam antibiotics against various MRSA and MSSA isolates, some even crossing the breakpoint from resistant to sensitive. GW779439X is an AURKA inhibitor and induces apoptosis by the caspases 3/7 pathway . MRSA:methicillin-resistant S. aureus; MSSA: methicillin-sensitive S. aureus
Referencia número: HY-P703126
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FLI1; Transcription Factor ERGB; Fli-1 Proto-Oncogene, ETS Transcription Factor; Ewing Sarcoma breakpoint Region 2; SIC-1; ERGB Transcription Factor; EWSR2; ERGB Transcription Fuctor; FLI-1; Proto-Oncogene Fli-1; Friend Leukemia Integration 1 Transcriptio
Species:
Human
Source:
E. coli
Referencia número: HY-P703127
Pureza: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: FLI1; Transcription Factor ERGB; Fli-1 Proto-Oncogene, ETS Transcription Factor; Ewing Sarcoma breakpoint Region 2; SIC-1; ERGB Transcription Factor; EWSR2; ERGB Transcription Fuctor; FLI-1; Proto-Oncogene Fli-1; Friend Leukemia Integration 1 Transcriptio
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
