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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
cardiovascular conditions
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "cardiovascular conditions" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: Diphosphofructose trisodium; Esafosfan trisodium; FDP trisodium
Category:
Cardiovascular Disease Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields
Target:
1
1
1 Cited Publications
Cat. No.: HY-W042301
CAS No.: 14293-44-8
Research Areas:
Xipamide is an orally active carbonic anhydrase (CA) inhibitor and Na +/Cl --potassium transporter inhibitor with diuretic and antihypertensive effects. Xipamide reduces NaCl reabsorption by inhibiting the Cl -/NaCO3 - anion exchanger, and increases calcium reabsorption while promoting potassium and magnesium excretion. Xipamide is mainly cleared via the renal pathway and causes a temporary decrease in glomerular filtration rate under specific conditions. Xipamide does not affect Ca 2+ signaling induced by endothelin-1 and other factors, nor does it inhibit various ion cotransport or pump activities in red blood cells. Xipamide can be used in researches related to cardiovascular diseases, hypertension (especially with left ventricular hypertrophy), advanced renal failure, and liver cirrhosis with ascites .
Cat. No.: HY-NP165
Synonyms: AGEs
Cat. No.: HY-P99139
Research Areas:
Research Areas:
Lignocaine N-oxide (Lidocaine N-oxide) is a hypoxia-activated prodrug of lidocaine (HY-B0185). Lignocaine N-oxide exerts exactly the same sodium current-blocking effect as lidocaine only when it is converted to lidocaine under ischemic conditions. Lignocaine N-oxide possesses antiarrhythmic activity against ischemia-induced ventricular fibrillation. Lignocaine N-oxide can be used in studies related to ischemia-induced ventricular fibrillation .
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Research Areas:
Bamethan (DL-Bamethane) hemisulfate is a vasodilator that exhibits significant activity in enhancing blood flow and reducing vascular resistance. Bamethan hemisulfate plays a crucial role in the treatment of cardiovascular conditions by improving oxygen delivery to tissues. Bamethan hemisulfate also aids in the management of hypertension through its relaxing effects on blood vessels.
Synonyms: Indoramine; Wy 21901
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease
Indoramin (Wy 21901) is a competitive and selective α1-adrenoceptor antagonist. Indoramin reduces peripheral vascular resistance, blood pressure, heart rate and myocardial contractility in experimental animals. Under hypoxic conditions, Indoramin increases ATP synthesis in brain tissue, maintains cerebral ATP levels, and alleviates hypoxia-related swelling of synaptosomes, cerebral microvessels and the whole brain. Indoramin can be used in studies related to hypertension, cardiovascular regulation and cerebral hypoxia .
Cat. No.: HY-W047191
CAS No.: 1198-69-2
Cat. No.: HY-P990294
Research Areas:
Cat. No.: HY-126293
CAS No.: 2227512-85-6
Target:
Research Areas:
Apelin agonist 1 is an oral selective apelin agonist AM-2995, a agonist of the APJ (APLNR, angiotensin receptor like-1) receptor, may be used in the treatment of cardiovascular conditions. Apelin agonist 1 is extracted from patent WO 2018097944 (210.0), Example 210.0 .
Cat. No.: HY-179106
CAS No.: 3035306-81-8
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PCSK9-IN-34 is a small molecule PCSK9 inhibitor. PCSK9-IN-34 can be used for research on cardiovascular conditions .
Cat. No.: HY-N15495
CAS No.: 60450-21-7
Target:
Cat. No.: HY-U00135
CAS No.: 136941-70-3
Target:
Research Areas:
Calcium channel-modulator-1 is an orally active calcium channel modulator that blocks aortic contraction with an IC50 of 0.8 μM. Calcium channel-modulator-1 can be used for the study of cardiovascular conditions .
Cat. No.: HY-179065
CAS No.: 882235-30-5
Target:
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VU0494372 is an activator of potassium ion channel KCNQ1. VU0494372 can significantly enhance the cell surface expression and transport efficiency of KCNQ1. VU0494372 does not alter KCNQ1 mRNA levels and protein degradation rate, and has no significant cytotoxicity. VU0494372 can be used for research on cardiovascular conditions .
Cat. No.: HY-105506
CAS No.: 114798-27-5
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Research Areas:
EXP-7711 is a non peptide angiotensin II (Ang II) AT1 receptor antagonist. EXP-7711’s affinity for wild-type AT1 receptor (Ki =180 nM) is lower than peptide antagonists, but higher than losartan (Ki = 12 nM). EXP-7711 can be used for research on cardiovascular conditions .
Cat. No.: HY-P11216
Synonyms: CI-337 (Standard); O-Diazoacetyl-L-serine (Standard); P-165 (Standard)
Bamethan (hemisulfate) (Standard) is the analytical standard of Bamethan (hemisulfate). This product is intended for research and analytical applications. Bamethan (DL-Bamethane) hemisulfate is a vasodilator that exhibits significant activity in enhancing blood flow and reducing vascular resistance. Bamethan hemisulfate plays a crucial role in the treatment of cardiovascular conditions by improving oxygen delivery to tissues. Bamethan hemisulfate also aids in the management of hypertension through its relaxing effects on blood vessels.
Cat. No.: HY-115876
CAS No.: 2145152-06-1
Target:
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
BTK-IN-5 is a covalent BTK inhibitor for researching medical conditions such as cardiovascular diseases, respiratory diseases, inflammation, and diabetes.
Cat. No.: HY-U00397
CAS No.: 890037-68-0
Target:
CB1 antagonist 1 is an antagonist of CB1 receptor, used in the research of metabolic syndrome and obesity, neuroinflammatory disorders, cognitive disorders and psychosis, gastrointestinal disorders, and cardiovascular conditions.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
