VU0494372
VU0494372 is an activator of potassium ion channel KCNQ1. VU0494372 can significantly enhance the cell surface expression and transport efficiency of KCNQ1. VU0494372 does not alter KCNQ1 mRNA levels and protein degradation rate, and has no significant cytotoxicity. VU0494372 can be used for research on cardiovascular conditions.
For research use only. We do not sell to patients.
- CAS No.: 882235-30-5
- Formula: C22H38N2O2
- Molecular Weight:362.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
Description
Chemical Information
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CAS No. 882235-30-5
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Molecular Weight 362.55
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Formula C22H38N2O2
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SMILES
CN1CCN(CC1)CC(COC2=CC=C(C=C2)C(C)(CC(C)(C)C)C)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Topics Targeted Protein Degradation (TPD): From PROTACs to Molecular Glues
Targeted protein degradation is a drug discovery strategy that uses cellular protein degradation systems to selectively eliminate disease-associated proteins, and its core modalities include PROTACs and molecular glue degraders.
2026-06-18
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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