36 Results for "

celiac

" in MedChemExpress (MCE) Product Catalog:
Products (36)

36 Results for "celiac" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-106268A
CAS No.: 881851-50-9
Purity:  99.74%
Research Areas:  

Inflammation/Immunology

Larazotide acetate is a peptide which is an orally active zonulin antagonist. Larazotide acetate shows antiviral activity to varicella-zoster virus (VZV) with EC50s of 44.14 and 59.06 μM for strain OKA and 07-1, respectively. Larazotide acetate can be used for the research of celiac disease and infection.
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4
4 Cited Publications
Cat. No.: HY-106268
CAS No.: 258818-34-7
Purity:  98.20%
Research Areas:  

Infection Inflammation/Immunology

Larazotideis a peptide which is an orally active zonulin antagonist. Larazotide shows antiviral activity to varicella-zoster virus (VZV) with EC50s of 44.14 and 59.06 μM for strain OKA and 07-1, respectively. Larazotide can be used for the research of celiac disease and infection .
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2
2 Cited Publications
Cat. No.: HY-N0384
CAS No.: 306-08-1
Synonyms: Vanilacetic acid
Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .
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2
2 Cited Publications
Cat. No.: HY-19359
CAS No.: 1542132-88-6
Synonyms: ZED-1227
Target:  

Glutaminase

Research Areas:  

Inflammation/Immunology

ZED-1227 is a specific and orally active transglutaminase 2 (TG2) inhibitor, with an IC50 of 45 nM. ZED-1227 can block inflammation-induced TG2 expression and activity. ZED-1227 can be used for the research of celiac disease (CeD) .
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1
1 Cited Publications
Cat. No.: HY-113166
CAS No.: 25518-54-1
Purity:  99.75%
Synonyms: (-)-Lauroylcarnitine
Dodecanoylcarnitine ((-)-Lauroylcarnitine) is a medium long-chain acylcarnitine, an intermediate product in key energy metabolic pathways of fatty acid β-oxidation and amino acids catabolism. The abnormal decrease in the Dodecanoylcarnitine levels indicats that mitochondrial fuel metabolism, including fatty acid oxidation is significantly disturbed. Changes in plasma concentrations of Dodecanoylcarnitine are not only associated with type II diabetes, but also with pre-diabetes status. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma. Combined model of Decanoylcarnitine (HY-113069), Dodecanoylcarnitine, PC (16:0/0:0), and Asp Arg Pro can be used as a potential biomarker for the diagnosis of Yin-deficiency-heat syndrome .
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1
1 Cited Publications
Cat. No.: HY-135783
CAS No.: 1314801-63-2
Purity:  99.94%
AT 1001 is an orally effective α3β4 nicotinic acetylcholine receptor (α3β4 nAChR) antagonist with a Ki value of 2.64 nM. AT 1001 reversibly blocks Epibatidine (HY-101078)-induced inward currents in HEK cells transfected with α3β4 nAChR. AT 1001 dose-dependently blocks nicotine self-administration behavior in rats, alleviates gluten-induced gastrointestinal symptoms, blocks tight junction toxin-induced immune responses, and reduces the incidence of type 1 diabetes in rats. AT 1001 can be used in the research of nicotine addiction and celiac disease .
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1
1 Cited Publications
Cat. No.: HY-113408
CAS No.: 64681-36-3
Purity:  99.92%
Tiglyl carnitine is found to be associated with celiac disease and mitochondrial acetoacetyl-CoA thiolase (T2) deficiency.
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Cat. No.: HY-P99410
CAS No.: 879293-15-9
Synonyms: AMG 714; PRV-015

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Ordesekimab (AMG 714; PRV-015) is a fully human IgG1κ anti-IL-15 (Interleukin Related) monoclonal antibody. The binding of Ordesekimab to IL-15 inhibits the interaction of IL-15 with the IL-2Rβ and common γ chain of the IL-15 receptor complex, but not with the IL-15Rα chain. Ordesekimab has the potential for study of nonresponsive celiac disease (NRCD) .
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Cat. No.: HY-P3151
CAS No.: 176326-01-5
Target:  

Peptides

Research Areas:  

Inflammation/Immunology

Gliadin p31-43 is an undigested gliadin peptide. Gliadin p31-43 induces an innate immune response in the intestine and interferes with endocytic trafficking. Gliadin p31-43 can be used for celiac disease research .
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Cat. No.: HY-113144
CAS No.: 22671-29-0
Purity:  99.53%
L-Hexanoylcarnitine is an acylcarnitine and is found to be associated with celiac disease.
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Cat. No.: HY-N0384S2
CAS No.: 53587-32-9
Synonyms: Vanilacetic acid-d5
Homovanillic acid-d5 (Vanilacetic acid-d5) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .
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Cat. No.: HY-W763569
CAS No.: 8002-80-0
Gluten, Wheat is a cohesive, visco-elastic proteinaceous material that can be extrated from wheat. Gluten, Wheat can be used to induce celiac disease .
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Cat. No.: HY-W355779
CAS No.: 9007-90-3
Synonyms: Tyrosylprolylglutaminylprolylglutamine
Gliadins (Tyrosylprolylglutaminylprolylglutamine) comprise a family of glutamine- and proline-rich monomeric proteins that plays an role in autoimmune disease, such as celiac disease .
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Cat. No.: HY-N0384R
CAS No.: 306-08-1
Synonyms: Vanilacetic acid (Standard)
Homovanillic acid (Standard) (Vanilacetic acid (Standard)) is the analytical standard of Homovanillic acid (HY-N0384). This product is intended for research and analytical applications. Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .
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Cat. No.: HY-Y1422B
CAS No.: 9001-62-1
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Lipase (MS grade) catalyzes the hydrolysis of triacylglycerols to release long-chain fatty acids in a site-specific manner. Lipase (MS grade) is involved in a variety of biological processes, from fat metabolism to cell signaling and inflammation, and can be used to study diseases such as pancreatic insufficiency, celiac disease and cystic fibrosis .
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Cat. No.: HY-113408R
CAS No.: 64681-36-3
Tiglyl carnitine (Standard) is the analytical standard of Tiglyl carnitine. This product is intended for research and analytical applications. Tiglyl carnitine is found to be associated with celiac disease and mitochondrial acetoacetyl-CoA thiolase (T2) deficiency.
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Cat. No.: HY-N0384S
CAS No.: 74495-71-9
Synonyms: Vanilacetic acid-d3
Homovanillic acid-d3 (Vanilacetic acid-d3) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .
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Cat. No.: HY-N0384S1
CAS No.: 53587-33-0
Synonyms: Vanilacetic acid-d2
Homovanillic acid-d2 (Vanilacetic acid-d2) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .
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Cat. No.: HY-177878
CAS No.: 2303528-97-2
Target:  

Sirtuin

Research Areas:  

Inflammation/Immunology

IMU-856 is an orally active and systemic action SIRT6 small molecule regulator. IMU-856 effectively and selectively inhibits the deacetylase activity of SIRT6, while increasing the protein level of SIRT6. IMU-856 can restore intestinal barrier function and can be used for research on celiac disease .
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Cat. No.: HY-P3151A
Research Areas:  

Inflammation/Immunology

Gliadin p31-43 TFA is an undigested gliadin peptide. Gliadin p31-43 TFA induces an innate immune response in the intestine and interferes with endocytic trafficking. Gliadin p31-43 TFA can be used for celiac disease research .
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