44 Results for "

chiral compound

" in MedChemExpress (MCE) Product Catalog:
Products (44)

44 Results for "chiral compound" in MCE Product Catalog:

Cat. No.: HY-40228
CAS No.: 196929-78-9
Synonyms: (R)-2-Methylpropane-2-sulfinamide
(R)-(+)-tert-Butylsulfinamide ((R)-2-Methylpropane-2-sulfinamide) is a chiral reagent commonly used in the asymmetric synthesis of compounds such as amines, amino acids, and amino alcohols. (R)-(+)-tert-Butylsulfinamide achieves stereoselective reactions by condensing with carbonyl groups to form sulfinyl imine intermediates, and after the reaction, this group can be removed under acidic conditions to obtain the target product .
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Cat. No.: HY-Y1131
CAS No.: 24915-95-5
Synonyms: Ethyl (R)-3-hydroxybutanoate
Ethyl (R)-3-hydroxybutyrate is an organic compound commonly used as a starting material for chiral chemical synthesis. It can be used in the preparation of medicines, spices, fine chemicals and food additives, etc., and is widely used in medicine, cosmetics and food industries. In addition, this compound is also used as a substrate or intermediate in some biochemical reactions
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Cat. No.: HY-Y0816
CAS No.: 17199-29-0
(S)-Mandelic Acid is a (S)-enantiomer of Mandelic Acid (HY-W015591). (S)-Mandelic Acid undergoes one-directional chiral inversion to (R)-Mandelic Acid in rat models. (S)-Mandelic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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Cat. No.: HY-P2834
CAS No.: 9014-06-6
Synonyms: PGA
Research Areas:  

Others

Penicillin amidase, E. coli (Immobilized) (PGA) is an amidohydrolase commonly used in industrial biocatalysis. Penicillin amidase, E. coli (Immobilized) serves as a starting material in the synthesis of semi-synthetic penicillins. Penicillin amidase, E. coli (Immobilized) promotes the production of semi-synthetic β-lactam antibiotics, participates in peptide synthesis, and catalyzes the formation of chiral compounds. Penicillin amidase, E. coli (Immobilized) is regulated by temperature and phenylacetic acid in E. coli. In free E. coli, it participates in the assimilation of aromatic compounds as a carbon source. Penicillin amidase, E. coli (Immobilized) is hypothesized to act as a scavenging enzyme for phenylacetyl-containing compounds in microbial metabolism and is associated with bacterial quorum sensing .
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Cat. No.: HY-40229
CAS No.: 343338-28-3
Synonyms: S-(-)-T-Butylsulfinimide
(S)-(-)-tert-Butylsulfinamide (S-(-)-T-Butylsulfinimide) is a compound containing a chiral sulfur atom. (S)-(-)-tert-Butylsulfinamide can be used in the synthesis of other compounds .
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Cat. No.: HY-69348
CAS No.: 102308-32-7
(S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is a chiral compound. (S)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is commonly used as a chiral intermediate in asymmetric synthesis and has important applications in the field of organic synthesis .
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Cat. No.: HY-W012874
CAS No.: 632-20-2
Synonyms: H-D-Thr-OH
D-Threonine (H-D-Thr-OH) is an important non-natural amino acid. D-Threonine serves as a chiral building block for the asymmetric synthesis of compounds. D-Threonine is a metabolite of Saccharomyces cerevisiae. D-Threonine is cleaved into glycine and acetaldehyde under the catalysis of D-threonine aldolase .
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Cat. No.: HY-W015998
CAS No.: 5543-58-8
(R)-(+)-Warfarin is an orally active chiral 4-hydroxycoumarin compound with vitamin K epoxide reductase (VKOR) inhibitory activity and cytochrome P450 substrate activity . (R)-(+)-Warfarin undergoes stereoselective metabolism via CYP1A2 to form 6-Hydroxywarfarin and 8-Hydroxywarfarin, and is metabolized via CYP3A4 to produce 10-Hydroxywarfarin (HY-134999). (R)-(+)-Warfarin can be used for the research of thromboembolic diseases .
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Cat. No.: HY-I0259
CAS No.: 118-46-7
8-Amino-2-naphthol is a photoactive charge transfer compounds, which can be used as fluorescent probe. 8-Amino-2-naphthol undergoes excited-state proton transfer (ESPT) to form a zwitterion under acidic conditions, where the photoacidity of its hydroxyl group is regulated by the protonation state of the amino group, enabling pH to act as an on/off switch for photoacidity. 8-Amino-2-naphthol is also utilized as chiral organocatalyst .
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Cat. No.: HY-24312
CAS No.: 153130-59-7
AD-mix-α is a mixture of organic compounds, commonly used to distinguish and identify asymmetric carbon atoms in chiral compounds. It consists of compounds containing catalytically active metals and chiral ligands. AD-mix-α is widely used in various organic synthesis reactions, such as hydrogenation, addition, and carbonylation reactions, to increase yield and reduce the formation of side reaction products. Although it has no direct application in the medical field, it plays an important role in the pharmaceutical industry and chemical research.
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Cat. No.: HY-W002878
CAS No.: 144222-34-4
TsDPEN (Compound 2) is a biochemical reagent. TsDPEN derivatives containing N,N,N imide chiral ligands can be applied to copper catalyzed asymmetric Kinugasa reactions .
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Cat. No.: HY-W012846A
CAS No.: 2319-57-5
Synonyms: L-1,2,3,4-Butanetetrol
L-Threitol (L-1,2,3,4-Butanetetrol) is a four-carbon sugar alcohol. L-Threitol serves as an important pharmaceutical intermediate and can be used in the synthesis of other active compounds, such as anticancer agents and chiral compounds .
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Cat. No.: HY-W010507
CAS No.: 3976-69-0
Synonyms: Methyl (R)-(-)-3-hydroxybutyrate
(R)-Methyl 3-hydroxybutanoate, (R)-Methyl 3-hydroxybutanoate is an enantiomer, from the perspective of the methyl (-CH3) group, the hydroxyl (-OH) group on the third carbon atom The group faces to the right, a colorless transparent liquid, soluble in organic solvents such as ethanol and ether, insoluble in water, (R)-Methyl 3-hydroxybutanoate is usually used to synthesize various organic compounds (including drugs, agricultural chemicals and flavoring agents) It can also be used as a chiral auxiliary in asymmetric synthetic reactions involving the formation of chemical bonds in a stereoselective manner.
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Cat. No.: HY-Y0549
CAS No.: 117-34-0
Synonyms: Diphenylmethane-α-carboxylic Acid
Diphenylacetic acid (Diphenylmethane-α-carboxylic Acid) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Diphenylacetic acid can be used as a reagent in the kinetic resolution of racemic 2-hydroxy-y-butyrolactones by asymmetric esterification in the presence of pivalic anhydride and chiral acyl-transfer catalyst. Diphenylacetic acid can act as a catalyst to synthesize 2-allyl-3-oxazolin-5-one derivatives via Rh-catalyzed coupling reaction of azlactones and alkynes followed by aza-Cope rearrangement .
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Cat. No.: HY-I0606B
CAS No.: 15186-48-8
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde is a chiral molecule with potential chiral catalytic activity. It can be used as an intermediate in organic synthesis and plays a key role in the construction of complex molecular systems. This compound has also been used to develop new compound carriers and exhibits good biocompatibility.
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Cat. No.: HY-16632
CAS No.: 1333990-84-3
Target:  

γ-secretase Amyloid-β

Research Areas:  

Metabolic Disease

ELND 006 (Compound 30) is a metabolically stable γ-secretase inhibitor designed to selectively inhibit amyloid beta (Aβ) generation while sparing Notch signaling. It was developed through a synthetic strategy emphasizing diversity and chirality. ELND 006, along with its analog ELND007 (Compound 34), progressed into human clinical trials. In preclinical studies, both compounds demonstrated effective reduction of Aβ levels in vitro and in vivo. Comparisons with other γ-secretase inhibitors like Semagacestat, Begacestat, and Avagacestat underscored their potency and specificity in lowering Aβ levels in cerebrospinal fluid (CSF) of healthy human volunteers, suggesting potential therapeutic efficacy in Alzheimer's disease .
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Cat. No.: HY-W142618
CAS No.: 13265-84-4
D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.
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Cat. No.: HY-W010394
CAS No.: 30414-53-0
Methyl 3-oxopentanoate, which is also known as diethyl acetylmalonate or MEAM, Methyl 3-oxopentanoate is commonly used as a building block for the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and flavorings, and it can also Used as a reagent in organic chemical reactions, especially the formation of carbon-carbon bonds through malonate synthesis, the researchers also investigated the potential use of Methyl 3-oxopentanoate in the development of chiral auxiliaries that can aid in the selection of Controlling the stereochemistry of chemical reactions.
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Cat. No.: HY-W015998S
CAS No.: 773005-79-1
(R)-(+)-Warfarin-d5 is the deuterated-labeled (R)-(+)-Warfarin (HY-W015998). (R)-(+)-Warfarin is an orally active chiral 4-hydroxycoumarin compound with vitamin K epoxide reductase (VKOR) inhibitory activity and cytochrome P450 substrate activity . (R)-(+)-Warfarin undergoes stereoselective metabolism via CYP1A2 to form 6-Hydroxywarfarin and 8-Hydroxywarfarin, and is metabolized via CYP3A4 to produce 10-Hydroxywarfarin (HY-134999). (R)-(+)-Warfarin can be used for the research of thromboembolic diseases .
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Cat. No.: HY-70027
CAS No.: 939981-37-0
Research Areas:  

Cancer

p53 and MDM2 protein-interaction inhibitor (chiral) (Compound 32) is an inhibitor of the interaction between p53 and MDM2. p53 and MDM2 protein-interaction inhibitor (chiral) has potential applications in cancer research .
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