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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
43 Results for "
citrate synthase
" in MedChemExpress (MCE) Product Catalog:
Products (43)
43 Results for "citrate synthase" in MCE Product Catalog:
9
Category:
Microorganisms Neurological Disease Anti-aging Amino acids Endogenous metabolite Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-N0473S9
CAS No.: 130551-49-4
1
1 Cited Publications
Cat. No.: HY-N0473S8
CAS No.: 72963-27-0
1
1 Cited Publications
Cat. No.: HY-N0473S4
CAS No.: 110622-46-3
1
1 Cited Publications
Cat. No.: HY-Q51222
CAS No.: 100264-64-0
Target:
Research Areas:
ZINC110492 is a selective ligand of CS-ΔEx4 (a splicing isoform of citrate synthase (CS)). ZINC110492 does not bind to CS full-length (CS-FL). ZINC110492 inhibits colorectal cancer (CRC) cell growth in cells overexpressing CS-ΔEx4 with an IC50 of 7.840 µM. ZINC110492 significantly decreases both citrate and 2-hydroxyglutarate (2-HG) levels in the CS-ΔEx4-overexpressing SW1116 cells .
1
1 Cited Publications
Cat. No.: HY-P72070
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACL; Acly; ACLY_HUMAN; ATP citrate pro-S; lyase; ATP citrate lyase; ATP citrate synthase; ATP-citrate pro-S-; -lyase; ATP-citrate synthase; ATPcitrate synthase; ATPCL; citrate cleavage enzyme; CLATP; OTTHUMP00000164773
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Research Areas:
Citrate synthase is responsible for catalyzing the first reaction of the citric acid cycle: the condensation of acetyl-CoA and oxaloacetate to form citrate. Citrate synthase is localized within eukaryotic cells in the mitochondrial matrix .
Cat. No.: HY-N0473S14
CAS No.: 1226919-57-8
Cat. No.: HY-N0473S
CAS No.: 62595-14-6
Cat. No.: HY-164027
CAS No.: 2614161-13-4
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Research Areas:
MyoMed 205 is an orally active muscle ring finger protein 1 (MuRF1) inhibitor. MyoMed-205 reduces ubiquitination and subsequent proteasomal degradation of muscle proteins by inhibiting MuRF1 activity. MyoMed 205 augments muscle performance, attenuates muscle weight loss and alleviates disease-induced weight loss. MyoMed 205 can be used for the research of cancer cachexia, type 2 diabetes mellitus, and heart failure with preserved ejection fraction .
Category:
Cat. No.: HY-N0473S1
CAS No.: 35424-81-8
Cat. No.: HY-N0473S2
CAS No.: 201595-63-3
Cat. No.: HY-N0473S13
CAS No.: 57746-15-3
Cat. No.: HY-N0473S3
CAS No.: 55443-60-2
Cat. No.: HY-E70394
CAS No.: 75179-85-0
Synonyms: Acetonyl-coenzyme A
Research Areas:
S-Acetonyl-CoA (Acetonyl-coenzyme A) is a non-reactive structural analog of acetyl-CoA that acts as a competitive inhibitor against multiple target enzymes. S-Acetonyl-CoA lacks the characteristic thioester group of acetyl-CoA, retaining only a thioether structure. S-Acetonyl-CoA competes with acetyl-CoA for binding to citrate synthase, phosphate transacetylase, carnitine acetyltransferase, and N-myristoyltransferase 1. S-Acetonyl-CoA serves as a reagent for investigating acetyl-CoA-dependent physiological processes .
Cat. No.: HY-P11358
CAS No.: 159718-10-2
Research Areas:
Cat. No.: HY-N0473S15
CAS No.: 71939-39-4
Cat. No.: HY-N0473S10
CAS No.: 30811-19-9
Cat. No.: HY-N0473S5
CAS No.: 81201-90-3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
