L-Tyrosine-d3
Based on 1 Customer Validation
L-Tyrosine-d3 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
For research use only. We do not sell to patients.
- Purity: 99.92%
- CAS No.: 71939-39-4
- Formula: C9H8D3NO3
- Molecular Weight:184.21
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 71939-39-4
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Unlabeled Cas 60-18-4
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Appearance Solid
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Molecular Weight 184.21
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Formula C9H8D3NO3
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Color White to off-white
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SMILES
OC([C@](N)([2H])CC1=C([2H])C=C(C=C1[2H])O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
1 M HCl : 12.5 mg/mL (67.86 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Ferreira GK, et al. Effect of L-tyrosine in vitro and in vivo on energy metabolism parameters in brain and liver of young rats. Neurotox Res. 2013 May;23(4):327-35. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| 1 M HCl | 1 mM | 5.4286 mL | 27.1429 mL | 54.2859 mL | 135.7147 mL |
| 5 mM | 1.0857 mL | 5.4286 mL | 10.8572 mL | 27.1429 mL | |
| 10 mM | 0.5429 mL | 2.7143 mL | 5.4286 mL | 13.5715 mL | |
| 15 mM | 0.3619 mL | 1.8095 mL | 3.6191 mL | 9.0476 mL | |
| 20 mM | 0.2714 mL | 1.3571 mL | 2.7143 mL | 6.7857 mL | |
| 25 mM | 0.2171 mL | 1.0857 mL | 2.1714 mL | 5.4286 mL | |
| 30 mM | 0.1810 mL | 0.9048 mL | 1.8095 mL | 4.5238 mL | |
| 40 mM | 0.1357 mL | 0.6786 mL | 1.3571 mL | 3.3929 mL | |
| 50 mM | 0.1086 mL | 0.5429 mL | 1.0857 mL | 2.7143 mL | |
| 60 mM | 0.0905 mL | 0.4524 mL | 0.9048 mL | 2.2619 mL |
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