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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
256 Results for "
clinical study
" in MedChemExpress (MCE) Product Catalog:
Products (256)
256 Results for "clinical study" in MCE Product Catalog:
1
Target:
Research Areas:
1
1
1 Cited Publications
Cat. No.: HY-D1223
Cat. No.: HY-P5238
CAS No.: 64577-63-5
Cat. No.: HY-D0563
CAS No.: 50925-42-3
Cat. No.: HY-14790
CAS No.: 98819-76-2
Synonyms: (S,S)-(+)-Reboxetine
Target:
Research Areas:
Esreboxetine ((S,S)-Reboxetine) is a selective norepinephrine reuptake inhibitor with activity in increasing urethral resistance. Esreboxetine has been reported to be effective in patients with stress urinary incontinence in a Phase IIa clinical study, achieving this effect by increasing urethral closure. The mechanism of action of esreboxetine involves inhibition of norepinephrine transporters in the central and peripheral nervous systems. The peripheral selectivity of esreboxetine helps it significantly increase urethral resistance without penetrating the brain .
Cat. No.: HY-D0087
CAS No.: 156571-46-9
Cat. No.: HY-D0783
CAS No.: 150322-02-4
Cat. No.: HY-D1032
CAS No.: 2230724-46-4
Cat. No.: HY-D0741
CAS No.: 83524-75-8
Cat. No.: HY-D0010
CAS No.: 16574-43-9
Synonyms: Dibromopyrogallolsulfonphthaleine
Cat. No.: HY-D0991
CAS No.: 221208-87-3
Cat. No.: HY-19500
CAS No.: 215122-74-0
SC-75416 is a selective cyclooxygenase-2 inhibitor. Its pharmacokinetic/pharmacodynamic (PK/PD) model was used for development and clinical trial simulation to design a study protocol to verify its analgesic effect in a post-oral surgery pain model. The simulation results showed that 360 mg of SC-75416 may provide better pain relief than 400 mg of ibuprofen. The actual clinical trial results confirmed this hypothesis, and 360 mg of SC-75416 was indeed superior to 400 mg of ibuprofen in pain relief. The PK/PD model of SC-75416 showed good predictive performance and successfully predicted its clinical effect. These research results show that SC-75416, as a new selective COX-2 inhibitor, has potential clinical application value in the management of post-oral surgery pain.
Cat. No.: HY-158763
CAS No.: 856242-63-2
Synonyms: TG0205221
Target:
Research Areas:
MPI8 (TG0205221) is an inhibitor of the major protease of SARS-CoV-2 (MPro) with high antiviral activity. MPI8 exerts its antiviral effect by dual and selective inhibition of SARS-CoV-2 MPro and host cell cysteine protease L (cathepsin L). MPI8 can be used in clinical studies of COVID-19 .
Cat. No.: HY-158763A
Synonyms: TG0205221 TFA
Target:
Research Areas:
MPI8 (TG0205221) TFA is an inhibitor of the major protease of SARS-CoV-2 (MPro) with high antiviral activity. MPI8 TFA exerts its antiviral effect by dual and selective inhibition of SARS-CoV-2 MPro and host cell cysteine protease L (cathepsin L). MPI8 TFA can be used in clinical studies of COVID-19 .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
