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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
conjunctival
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "conjunctival" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: R 50547 hydrochloride
Research Areas:
Levocabastine (R 50547) hydrochloride is a potent and selective histamine H1-receptor antagonist. Levocabastine hydrochloride is also a selective, high affinity neurotensin receptor subtype 2 (NTR2) antagonist, with a Ki of 17 nM for mNTR2. Levocabastine hydrochloride can act as a VLA-4 antagonist, interferes with conjunctival eosinophil infiltration in allergic conjunctivitis (AC) .
Cat. No.: HY-172435
CAS No.: 1431754-15-2
Synonyms: AGN-232411; AG-80308; AGN-411
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Research Areas:
Rezuforimod (AGN-232411; AG-80308) is an ophthalmic solution targeting the formyl peptide receptor (FPR) pathway. Rezuforimod exerts anti-inflammatory effects by targeting the formyl peptide receptor pathway. Administered topically, Rezuforimod significantly reduces the corneal conjunctival staining score and improves ocular discomfort symptoms, with no serious adverse events reported and favorable overall safety profile. Rezuforimod shows remarkable potential to serve as a novel therapeutic option for dry eye disease .
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Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion .
Synonyms: FPL 59002
Target:
Research Areas:
Nedocromil (FPL 59002) is a mast cell stabilizer and an inhibitor of IL-8 production. Nedocromil inhibits mast cell degranulation and collagen synthesis induced by activated mast cells, indirectly interfering with IL-1β signaling. Nedocromil reduces conjunctival eosinophil infiltration and improves the cutaneous manifestations of chronic graft-versus-host disease (including reducing fibrosis, loss of fat and hair follicles, and inflammatory infiltration). Nedocromil can be used in research on chronic graft-versus-host disease, asthma, and allergic conjunctivitis .
Cat. No.: HY-14277
CAS No.: 79516-68-0
Synonyms: R 50547
Research Areas:
Levocabastine (R 50547) is a potent and selective histamine H1-receptor antagonist. Levocabastine hydrochloride is also a selective, high affinity neurotensin receptor subtype 2 (NTR2) antagonist, with a Ki of 17 nM for mNTR2. Levocabastine can act as a VLA-4 antagonist, interferes with conjunctival eosinophil infiltration in allergic conjunctivitis (AC) .
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Research Areas:
17-Phenyl trinor PGF2α isopropyl ester is a FP receptor agonist and intraocular pressure-lowering agent. 17-Phenyl trinor PGF2α isopropyl ester induces iris sphincter contraction, reduces intraocular pressure and pupil diameter, causes no ocular irritation, and only leads to mild conjunctival hyperemia. 17-Phenyl trinor PGF2α isopropyl ester is applicable to relevant research on glaucoma .
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Research Areas:
Tetrahydrozoline (Tetryzoline), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion .
Cat. No.: HY-B0556AS
CAS No.: 1246814-66-3
Synonyms: Tetryzoline-d4 hydrochloride
Cat. No.: HY-B0556B
CAS No.: 118201-38-0
Synonyms: Tetryzoline nitrate
Target:
Research Areas:
Tetrahydrozoline (Tetryzoline) nitrate , a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion .
Cat. No.: HY-123195
CAS No.: 197917-10-5
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CK-119 is a potent interleukin-1 blocker. CK-119 inhibits the cell growth of fibroblast-like corneal and conjunctival cells, mainly by inhibiting DNA and RNA syntheses .
Cat. No.: HY-B0556AR
CAS No.: 522-48-5
Synonyms: Tetryzoline hydrochloride (Standard)
Research Areas:
Tetrahydrozoline (hydrochloride) (Standard) is the analytical standard of Tetrahydrozoline (hydrochloride). This product is intended for research and analytical applications. Tetrahydrozoline hydrochloride (Tetryzoline hydrochloride), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline hydrochloride is widely used for the research of nasal congestion and conjunctival congestion .
Research Areas:
Tetrahydrozoline (Standard) is the analytical standard of Tetrahydrozoline. This product is intended for research and analytical applications. Tetrahydrozoline (Tetryzoline), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion .
Cat. No.: HY-106037
CAS No.: 53764-90-2
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Research Areas:
PGF2α-isopropyl ester is a Prostaglandin F2α (HY-12956) derivative, which is active in lowering the intraocular pressure (IOP) through increased uveoscleral outflow of aqueous humor. PGF2α-isopropyl ester causes side effects of conjunctival hyperemia and ocular irritation .
Cat. No.: HY-14277AR
CAS No.: 79547-78-7
Synonyms: R 50547 hydrochloride (Standard)
Research Areas:
Levocabastine (hydrochloride) (Standard) is the analytical standard of Levocabastine (hydrochloride). This product is intended for research and analytical applications. Levocabastine (R 50547) hydrochloride is a potent and selective histamine H1-receptor antagonist. Levocabastine hydrochloride is also a selective, high affinity neurotensin receptor subtype 2 (NTR2) antagonist, with a Ki of 17 nM for mNTR2. Levocabastine hydrochloride can act as a VLA-4 antagonist, interferes with conjunctival eosinophil infiltration in allergic conjunctivitis (AC) .
Cat. No.: HY-13448R
CAS No.: 69049-73-6
Synonyms: FPL 59002 (Standard)
Research Areas:
Nedocromil (FPL 59002) (Standard) is the analytical standard of Nedocromil (HY-13448). This product is intended for research and analytical applications. Nedocromil (FPL 59002) calcium is a mast cell stabilizer and an inhibitor of IL-8 production. Nedocromil calcium inhibits mast cell degranulation and collagen synthesis induced by activated mast cells, indirectly interfering with IL-1β signaling. Nedocromil calcium reduces conjunctival eosinophil infiltration and improves the cutaneous manifestations of chronic graft-versus-host disease (including reducing fibrosis, loss of fat and hair follicles, and inflammatory infiltration). Nedocromil calcium can be used in research on chronic graft-versus-host disease, asthma, and allergic conjunctivitis .
Cat. No.: HY-109141
CAS No.: 1498299-91-4
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Research Areas:
Voluloride is a conjunctival epithelial cell sodium channel (ENaC) blocker. Voluloride can be used for the study of eye diseases .
Cat. No.: HY-13448A
CAS No.: 101626-68-0
Synonyms: FPL 59002 calcium
Target:
Research Areas:
Nedocromil (FPL 59002) calcium is a mast cell stabilizer and an inhibitor of IL-8 production. Nedocromil calcium inhibits mast cell degranulation and collagen synthesis induced by activated mast cells, indirectly interfering with IL-1β signaling. Nedocromil calcium reduces conjunctival eosinophil infiltration and improves the cutaneous manifestations of chronic graft-versus-host disease (including reducing fibrosis, loss of fat and hair follicles, and inflammatory infiltration). Nedocromil calcium can be used in research on chronic graft-versus-host disease, asthma, and allergic conjunctivitis .
Cat. No.: HY-176859
[Ru(dpp)(bpy)(mtmp)](PF6)2 (Compound 5) is a trisheteroleptic ruthenium complex. [Ru(dpp)(bpy)(mtmp)](PF6)2 has a light-activated anticancer activity. [Ru(dpp)(bpy)(mtmp)](PF6)2 can selectively cleave off upon green light irradiation, thereby releasing a phototoxic ruthenium-based photoproduct that binds to nuclear DNA, induces DNA damage and apoptosis in cancer cells. [Ru(dpp)(bpy)(mtmp)](PF6)2 can be used for phototherapy of cancers like conjunctival melanoma research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
