3 Results for "

cysteinyl leukotriene metabolite

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "cysteinyl leukotriene metabolite" in MCE Product Catalog:

Cat. No.: HY-113465S
CAS No.: 1240398-14-4
Synonyms: LTE4-d5
Leukotriene E4-d5 (LTE4-d5) is the d-5-labeled Leukotriene E4 (HY-113465). Leukotriene E4 is a stable final metabolite of cysteinyl leukotrienes, produced by immune cells such as mast cells and eosinophils. Leukotriene E4 serves as a key biomarker for evaluating asthma severity, Aspirin (HY-14654) sensitivity, and mast cell activation disorders. Leukotriene E4 is a full functional agonist of CysLT1R, which induces sustained intracellular calcium mobilization and Erk phosphorylation. Leukotriene E4 mediates inflammation in a P2Y12 receptor-dependent manner. Leukotriene E4 can be used in the research of asthma and non-steroidal anti-inflammatory drug-exacerbated respiratory diseases .
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Cat. No.: HY-113456S
CAS No.: 1240398-17-7
Purity:  98.4%
Leukotriene D4-d5 is the deuterium labeled Leukotriene D4. Leukotriene D4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. Leukotriene D4 is the first cysteinyl-leukotriene metabolite of LTC4. Leukotriene D4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity.
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Cat. No.: HY-171831
CAS No.: 79494-05-6
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

Leukotriene E3 is a cysteinyl leukotriene metabolite derived from 5,8,11-eicosatrienoic acid (HY-108398A). Leukotriene E3 acts as a smooth-muscle-contracting mediator. Leukotriene E3 can be used for the research of allergic reactions and asthma .
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