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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
dkk wnt inhibitor
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "dkk wnt inhibitor" in MCE Product Catalog:
13
11
11 Cited Publications
Cat. No.: HY-P7155A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: dkk1; Dickkopf 1 Homolog (Xenopus Laevis); Dickkopf wnt Signaling Pathway inhibitor 1; Dickkopf 1 Homolog; SK; Dickkopf-1 Like; dkk-1; Dickkopf-1; Dickkopf-Related Protein 1; Hdkk-1; Dickkopf-Like Protein 1; dkk-1; Dickkopf (Xenopus Laevis) Homolog 1
Species:
Human
Source:
HEK293
6
6 Cited Publications
Cat. No.: HY-P7154
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: dkk1; Dickkopf 1 Homolog (Xenopus Laevis); Dickkopf wnt Signaling Pathway inhibitor 1; Dickkopf 1 Homolog; SK; Dickkopf-1 Like; dkk-1; Dickkopf-1; Dickkopf-Related Protein 1; Hdkk-1; Dickkopf-Like Protein 1; dkk-1; Dickkopf (Xenopus Laevis) Homolog 1
Species:
Mouse
Source:
CHO
5
5 Cited Publications
Cat. No.: HY-P72968
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: dkk1; Dickkopf 1 Homolog (Xenopus Laevis); Dickkopf wnt Signaling Pathway inhibitor 1; Dickkopf 1 Homolog; SK; Dickkopf-1 Like; dkk-1; Dickkopf-1; Dickkopf-Related Protein 1; Hdkk-1; Dickkopf-Like Protein 1; dkk-1; Dickkopf (Xenopus Laevis) Homolog 1
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P72969
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: dkk1; Dickkopf 1 Homolog (Xenopus Laevis); Dickkopf wnt Signaling Pathway inhibitor 1; Dickkopf 1 Homolog; SK; Dickkopf-1 Like; dkk-1; Dickkopf-1; Dickkopf-Related Protein 1; Hdkk-1; Dickkopf-Like Protein 1; dkk-1; Dickkopf (Xenopus Laevis) Homolog 1
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P70513
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: dkk1; Dickkopf 1 Homolog (Xenopus Laevis); Dickkopf wnt Signaling Pathway inhibitor 1; Dickkopf 1 Homolog; SK; Dickkopf-1 Like; dkk-1; Dickkopf-1; Dickkopf-Related Protein 1; Hdkk-1; Dickkopf-Like Protein 1; dkk-1; Dickkopf (Xenopus Laevis) Homolog 1
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P73305
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: dkk1; Dickkopf 1 Homolog (Xenopus Laevis); Dickkopf wnt Signaling Pathway inhibitor 1; Dickkopf 1 Homolog; SK; Dickkopf-1 Like; dkk-1; Dickkopf-1; Dickkopf-Related Protein 1; Hdkk-1; Dickkopf-Like Protein 1; dkk-1; Dickkopf (Xenopus Laevis) Homolog 1
Species:
Rat
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P73305A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: dkk1; Dickkopf 1 Homolog (Xenopus Laevis); Dickkopf wnt Signaling Pathway inhibitor 1; Dickkopf 1 Homolog; SK; Dickkopf-1 Like; dkk-1; Dickkopf-1; Dickkopf-Related Protein 1; Hdkk-1; Dickkopf-Like Protein 1; dkk-1; Dickkopf (Xenopus Laevis) Homolog 1
Species:
Rat
Source:
HEK293
Synonyms: SK3530
Research Areas:
Mirodenafil (SK3530) is an orally active, potent, reversible, and selective phosphodiesterase 5 (PDE5) inhibitor. Mirodenafil is a glucocorticoid receptor (GR) modulator Mirodenafil activates the Wnt/β-catenin signaling pathway by downregulating Dkk1 expression. Mirodenafil can be used for the research of erectile dysfunction (ED), Alzheimer’s disease (AD) and systemic sclerosis (SSc) .
Target:
Research Areas:
Gallocyanine chloride is a synthetic blue dyestuff that can be used as a potential agent for the research of Alzheimer's disease and related neurodegenerative tauopathies. Gallocyanine chloride inhibits DKK1/LRP6 interaction (IC50=6.38 μM), activates Wnt signaling pathway, and causes β-catenin accumulation. Gallocyanine chloride exhibits anti-metastasis, anti-inflammatory and anti-fibrosis activities. Gallocyanine chloride can be used as a fluorescent probe for detection of superoxide anion radicals .
Synonyms: SK-3530 dihydrochloride
Research Areas:
Mirodenafil (SK3530) dihydrochloride is an orally active, potent, reversible, and selective phosphodiesterase 5 (PDE5) inhibitor. Mirodenafil dihydrochloride is a glucocorticoid receptor (GR) modulator Mirodenafil dihydrochloride activates the Wnt/β-catenin signaling pathway by downregulating Dkk1 expression. Mirodenafil dihydrochloride can be used for the research of erectile dysfunction (ED), Alzheimer’s disease (AD) and systemic sclerosis (SSc) .
Cat. No.: HY-14930R
CAS No.: 862189-95-5
Synonyms: SK3530 (Standard)
Research Areas:
Mirodenafil (Standard) is the analytical standard of Mirodenafil. This product is intended for research and analytical applications. Mirodenafil (SK3530) is an orally active, potent, reversible, and selective phosphodiesterase 5 (PDE5) inhibitor. Mirodenafil is a glucocorticoid receptor (GR) modulator Mirodenafil activates the Wnt/β-catenin signaling pathway by downregulating Dkk1 expression. Mirodenafil can be used for the research of erectile dysfunction (ED), Alzheimer’s disease (AD) and systemic sclerosis (SSc) .
Cat. No.: HY-P991569
Target:
Research Areas:
Cat. No.: HY-14930AR
CAS No.: 862189-96-6
Synonyms: SK-3530 dihydrochloride (Standard)
Research Areas:
Mirodenafil (dihydrochloride) (Standard) is the analytical standard of Mirodenafil (dihydrochloride). This product is intended for research and analytical applications. Mirodenafil (SK3530) dihydrochloride is an orally active, potent, reversible, and selective phosphodiesterase 5 (PDE5) inhibitor. Mirodenafil dihydrochloride is a glucocorticoid receptor (GR) modulator Mirodenafil dihydrochloride activates the Wnt/β-catenin signaling pathway by downregulating Dkk1 expression. Mirodenafil dihydrochloride can be used for the research of erectile dysfunction (ED), Alzheimer’s disease (AD) and systemic sclerosis (SSc) .
Research Areas:
Gallocyanine (NCI8642) is a DKK/LRP interaction inhibitor and Wnt/β-catenin signaling pathway activator. Gallocyanine binds to the YWTD repeat domains of LRP5/6, competitively blocks the interaction between DKK and LRP5/6, with an IC50 of approximately 3 μM for inhibiting DKK1 binding to LRP5, an IC50 of 6.38 μM for inhibiting DKK1 binding to LRP6, and a Ki of 14 μM for inhibiting the DKK2C/LRP6-E3E4 interaction. Gallocyanine reverses the inhibitory effect of DKK1 on WNT3A signaling, with an EC50 of approximately 5 μM. Gallocyanine can be used in studies related to Alzheimer's disease, bone formation and glucose metabolism .
Cat. No.: HY-P7812
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: dkk3; Hdkk-3; Dickkopf wnt Signaling Pathway inhibitor 3; dkk-3; REIC; Dickkopf wnt Signaling Pathway inhibitor 3; Dickkopf-Related Protein 3; Dickkopf (Xenopus Laevis) Homolog 3; CRRL; Dickkopf 3 Homolog (Xenopus Laevis); RIG; Dickkopf 3 Homolog; Cardiom
Species:
Human
Source:
HEK293
Cat. No.: HY-P75287
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: dkk3; Hdkk-3; Dickkopf wnt Signaling Pathway inhibitor 3; dkk-3; REIC; Dickkopf wnt Signaling Pathway inhibitor 3; Dickkopf-Related Protein 3; Dickkopf (Xenopus Laevis) Homolog 3; CRRL; Dickkopf 3 Homolog (Xenopus Laevis); RIG; Dickkopf 3 Homolog; Cardiom
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P78681
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: dkk3; Hdkk-3; Dickkopf wnt Signaling Pathway inhibitor 3; dkk-3; REIC; Dickkopf wnt Signaling Pathway inhibitor 3; Dickkopf-Related Protein 3; Dickkopf (Xenopus Laevis) Homolog 3; CRRL; Dickkopf 3 Homolog (Xenopus Laevis); RIG; Dickkopf 3 Homolog; Cardiom
Species:
Human
Source:
HEK293
Cat. No.: HY-P77640
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: dkk3; Hdkk-3; Dickkopf wnt Signaling Pathway inhibitor 3; dkk-3; REIC; Dickkopf wnt Signaling Pathway inhibitor 3; Dickkopf-Related Protein 3; Dickkopf (Xenopus Laevis) Homolog 3; CRRL; Dickkopf 3 Homolog (Xenopus Laevis); RIG; Dickkopf 3 Homolog; Cardiom
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
