Search Result
Results for "
doping
" in MedChemExpress (MCE) Product Catalog:
60
Biochemical Assay Reagents
3
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-112005
-
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Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
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Liposome
Endogenous Metabolite
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Inflammation/Immunology
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DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
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-
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- HY-141613
-
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DOPS-NA
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Liposome
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Others
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1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) is a ubstitute for Phosphoserine/phosphatidylserine. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can be used together with DOPC and DOPE in lipid mixtures for the synthesis of liposomes. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can self-assemble into single-layer or double-layer membrane structures, similar to cell membranes, and possesses high membrane fluidity and flexibility. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine is widely applied in membrane biology, cell membrane research, lipid preparation, and drug delivery systems .
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- HY-121252
-
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α-synuclein
Apoptosis
Drug Metabolite
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Neurological Disease
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Dopal is a metabolite and aldehyde neurotoxin of Dopamine (HY-B0451). Dopal exhibits cytotoxicity, induces α-synuclein oligomerization and aggregation, and is closely associated with the pathogenesis of Parkinson's disease. Dopal can be used in research related to Parkinson's disease .
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- HY-150241
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- HY-W416291
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Poly(A)
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Biochemical Assay Reagents
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Cancer
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Polyadenylic acid potassium, also known as Poly(A), is enzymatically added to messenger RNA (mRNA) in eukaryotic cells to stabilize mRNAs. Poly(A) is used to evaluate binding on cationic liposomes doped with non-ionic nucleolipids. Poly(A) is used in small molecule mRNA targeted drug development to evaluate the binding of potential therapeutic agents such as the Isoquinoline group of alkaloids. Small molecules that could bind to this poly(A) tail could influence and possibly inhibit mRNA function and subsequent protein production in the cell leading to the development of new type of therapeutic agents.
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- HY-144010
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DOPE-PEG2000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
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Liposome
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Others
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18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) can be used for drug delivery .
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- HY-142997
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Liposome
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Cancer
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DOSPA is a cationic lipid. DOSPA can form lipid nanoparticles with DOPE (HY-112005) to serve as a carrier for nucleic acid transfection. DOSPA is applicable in research related to drug delivery .
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- HY-130479
-
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Adiponectin Receptor
PPAR
PGC-1α
Sirtuin
AMPK
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Metabolic Disease
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AdipoR agonist 1 (Compound 112254) is an agonist for adiponectin receptor (AdipoR), which activates the transcriptional regulators like peroxisome proliferator-activated receptors (PPARs), peroxisome proliferator-activated receptor gamma coactivator 1α (PGC-1α), sirtuin 1 (SIRT1), and adenylate-activated protein kinase (AMPK). AdipoR agonist 1 is utilized in preventive doping research .
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- HY-W440988
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Liposome
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Others
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DOPE-mPEG2000 is a phospholipid polydisperse PEG (or DOPE liposome), can be used for preparation of targeted delivery of liposomal drug and giant unilamellar vesicles (GUVs). DOPE-mPEG2000 significantly reduces the pH-sensitivity of the liposome in a concentration dependent manner .
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- HY-N16025
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Liposome
Biochemical Assay Reagents
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Others
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DOPE-PEG(2000) Amine ammonium is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted agent delivery and is reactive with alkyne to form a triazole ring .
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- HY-W440827
-
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Liposome
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Others
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DOPE-PEG2000-COOH is a PEG polymer containing unsaturated DOPE phospholipids and carboxylic acids. DOPE-PEG2000-COOH can be used to prepare liposomes or other nanoparticles for drug delivery .
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- HY-164035
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Biochemical Assay Reagents
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Others
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DOPE-PEG2000-DBCO is a PEG lipid with a DOPE and a DBCO as functional groups. DOPE can be used as a helper lipid in gene transfection. PEG is used in drug delivery system. DBCO can be used for click chemistry .
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- HY-166883
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- HY-21170B
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Triflate lithium; Trifluoromethylsulfonate lithium; Trifluoromethanesulphonic acid lithium
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Biochemical Assay Reagents
Herbicide
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Others
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Trifluoromethanesulfonate (Triflate;Trifluoromethylsulfonate) lithium is a stable lithium salt and dopant with four resonance states, which is commonly used as an electrolyte component in polymer light-emitting electrochemical cells and primary lithium batteries. Trifluoromethanesulfonate lithiumalso acts as a catalyst for the preparation of the herbicide Imazapyr. In MEH-PPV-based light-emitting electrochemical cells, Trifluoromethanesulfonate lithium promotes electrochemical p-type doping at the anode interface under applied bias, thereby facilitating the formation of p-i-n junctions, exciton generation, and light emission. Trifluoromethanesulfonate lithiumexhibits strong ion pairing in non-aqueous electrolytes, but its electrochemical stability window is narrower than that of lithium bistrifluoromethylsulfonyl imidee .
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- HY-N12762
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Liposome
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Others
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DGTS, as described, is a structural isomer of DGTA and one of the most common betaine lipids found in microalgae, particularly abundant in Chlorophyceae . DGTS is a helper lipid that is structurally similar to DSPE or DOPE.
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- HY-W800805
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Liposome
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Cancer
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DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.
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- HY-D0948
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Fluorescent Dye
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Infection
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Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO2 nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen .
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- HY-137499
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Liposome
Endogenous Metabolite
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Neurological Disease
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NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .
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- HY-W440987
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Biochemical Assay Reagents
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Others
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DOPE-mPEG1000 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations to achieve better therapeutic effects. DOPE-mPEG1000 can be used in drug delivery research .
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- HY-W440995
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Liposome
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Cancer
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DOPE-PEG2000-Mal is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. It is also reactive with thiol at pH 6.5 tp 7.5 to form a stable thioether bond.
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- HY-160272
-
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Fluorescent Dye
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Others
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DOPE-PEG2000-Fluor 488 is a PEG lipid, composed of a DOPE phospholipid and a Fluor 488 fluorophore. DOPE is an unsaturated phospholipid. Fluor 488 has excitation and emission maxima at 499 nm and 520 nm .
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- HY-160280
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- HY-112005GL
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Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)
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Liposome
Endogenous Metabolite
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Inflammation/Immunology
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DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
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- HY-121252A
-
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α-synuclein
Apoptosis
Drug Metabolite
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Neurological Disease
|
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Dopal (purity>80%) is a metabolite and aldehyde neurotoxin of Dopamine (HY-B0451). Dopal (purity>80%) exhibits cytotoxicity, induces α-synuclein oligomerization and aggregation, and is closely associated with the pathogenesis of Parkinson's disease. Dopal (purity>80%) can be used in research related to Parkinson's disease .
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- HY-N15995
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Biochemical Assay Reagents
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Others
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DOPE-PEG(2000) Carboxylic acid sodium is a stabilizer. DOPE-PEG(2000) Carboxylic acid sodium produce a coating around the ferrofluid droplet chains which are dispersed in 5CB. DOPE-PEG(2000) Carboxylic acid sodium tends to fold, effectively shielding the surrounding LC molecules from the homeotropic anchoring at the droplet interface and leading to smaller deformations and thus also creating a more stable interface .
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- HY-W591450
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Biochemical Assay Reagents
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Others
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DOPE-PEG3400-Azide is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG3400-Azidecan be used in drug delivery research .
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- HY-W591448
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Biochemical Assay Reagents
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Others
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DOPE-PEG1000-Azide is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG1000-Azidecan be used in drug delivery research .
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- HY-150240
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Liposome
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Cancer
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DOPE-GA can be used in the preparation of liposomes for research on drug delivery and other applications .
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- HY-N15907
-
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Liposome
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Others
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DOPE PEG(2000)-N-Cyanine 5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE PEG(2000)-N-Cyanine 5 can be used in drug delivery research.
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- HY-155934
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DOPE-PEG5000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
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Liposome
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Others
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18:1 PEG5000 PE ammonium (DOPE-PEG5000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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- HY-175410
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1,2-Dioloeoyl-sn-glycero-3-phosphoethanolamine-C8; 1,2-DOPE-C8
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Liposome
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Others
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DOPE-C8 (1,2-Dioloeoyl-sn-glycero-3-phosphoethanolamine-C8; 1,2-DOPE-C8) is a zwitterionic phospholipid derived from DOPE that has been used to generate lipid nanoparticles (LNPs) for in vivo delivery of mRNA .
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- HY-N15803
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Biochemical Assay Reagents
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Cancer
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DOPE-RGD Lipid sodium is a lipid containing DOPE and RGD peptides that can be used to prepare lipid nanoparticles for drug delivery.
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- HY-160273
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- HY-W440996
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Biochemical Assay Reagents
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Others
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DOPE-PEG3400-Mal is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG3400-Malcan be used in drug delivery research .
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- HY-166852
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Biochemical Assay Reagents
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Others
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DOPE-PEG2000-Cy5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-Cy5can be used in drug delivery research .
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- HY-129990
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Liposome
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Cancer
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Dios-Arg diTFA, a cationic lipid with an arginine-bearing headgroup, shows obvious double bond proton signals at around 5.2-5.3 ppm. Dios-Arg diTFA is used, coupled to DOPE, to bind siRNA and plasmid to for cationic LNPs for intracellular transport .
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- HY-158705
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Liposome
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Others
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SAINT-2 is a cationic lipid with gene transfection activity and is a pyridyl lipid analog. Molecular membranes prepared by SAINT-2 can interact with plasmids to form lipid complexes. After the complex is taken up by cells, the plasmid dissociates from the lipid complex under the action of DOPE and the plasmid translocates across the endosome and/or nuclear membrane. Thus, SAINT-2 effectively transfers small oligonucleotides into cells .
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- HY-W591449
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Liposome
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Cancer
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DOPE-PEG2000-Azide is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
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- HY-155931
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DOPE-PEG550 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
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Liposome
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Others
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18:1 PEG550 PE ammonium (DOPE-PEG550 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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- HY-155933
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DOPE-PEG3000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
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Liposome
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Others
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18:1 PEG3000 PE ammonium (DOPE-PEG3000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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- HY-155932
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DOPE-PEG1000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
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Liposome
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Others
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18:1 PEG1000 PE ammonium (DOPE-PEG1000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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- HY-155930
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DOPE-PEG350 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
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Liposome
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Others
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18:1 PEG350 PE ammonium (DOPE-PEG350 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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- HY-160275
-
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Liposome
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Others
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DOPE-PEG2000-Fluor 555 is a PEG-lipid-dye conjugate featuring a DOPE phospholipid and a Fluor 555 dye. DOPE (HY-112005) is a neutral helper lipid for cationic liposome. Fluor 555 is a fluorescent dye .
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- HY-160573
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Liposome
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Others
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cKK-E15 is a peptide-lipid that can be used to formulate LNP3 with C14PEG2000, unmodified cholesterol, and DOPE .
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- HY-121252S
-
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Isotope-Labeled Compounds
α-synuclein
Apoptosis
Drug Metabolite
|
Neurological Disease
|
|
Dopal-d5 is the deuterium labeled Dopal (HY-121252). Dopal is a metabolite and aldehyde neurotoxin of Dopamine (HY-B0451). Dopal exhibits cytotoxicity, induces α-synuclein oligomerization and aggregation, and is closely associated with the pathogenesis of Parkinson's disease. Dopal can be used in research related to Parkinson's disease .
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- HY-159004
-
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Reactive Oxygen Species (ROS)
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Metabolic Disease
Inflammation/Immunology
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Se-DOPE is a phospholipid molecule with selenium. Se-DOPE can be used to synthesize the bifunctional Janus liposozyme. Se-DOPE promotes the production of ROS with induction of lights, scavenges the ROS with the presence of glutathione. Se-DOPE regulates redox and immune homeostasis in infected diabetic wounds .
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- HY-N16036
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Biochemical Assay Reagents
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Others
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DOPE-PEG(2000)-HALO-TAG ammonium is a PEG polymer containing unsaturated DOPE phospholipids. DOPE-PEG(2000)-HALO-TAG ammonium can be used to prepare liposomes or other nanoparticles for drug delivery.
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- HY-166323
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- HY-167031
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Biochemical Assay Reagents
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Others
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DOPE-PEG5000-DBCO is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DOPE-PEG5000-DBCO can be used in drug delivery research .
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- HY-160276
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Liposome
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Others
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DOPE-PEG5000-Fluor 555 is consist of a DOPE phospholipid which is an unsaturated phospholipid and a Fluor 555 dye which is a bright orange cyanine dye that can be used in fluorescence microscopy, FRET and other in vivo imaging techniques.
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- HY-173383
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1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt
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Biochemical Assay Reagents
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Inflammation/Immunology
Cancer
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DOPE-DOTA sodium is a chelated lipid that serves as a key contrast agent in magnetic resonance imaging (MRI). DOPE-DOTA sodium can be used for cancer, blood-brain barrier disruption, abnormalities such as aneurysms or plaque buildup, inflammation in arthritis, and liver function and lesions study
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- HY-160542
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Endogenous Metabolite
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Others
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Clenhexyl hydrochloride is a urinary metabolite useful for quantitative screening in doping control screening programs .
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- HY-W440997
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Biochemical Assay Reagents
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Others
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DOPE-PEG5000-Mal is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-Malcan be used in drug delivery research .
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- HY-166846
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Biochemical Assay Reagents
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Others
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DOPE-PEG2000-FITC is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-FITCcan be used in drug delivery research .
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- HY-166833
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Biochemical Assay Reagents
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Others
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DOPE-PEG5000-Rhodamine B is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-Rhodamine Bcan be used in drug delivery research .
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- HY-166849
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Biochemical Assay Reagents
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Others
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DOPE-PEG5000-Cy5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-Cy5can be used in drug delivery research .
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- HY-166848
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Biochemical Assay Reagents
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Others
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DOPE-PEG2000-Cy5.5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-Cy5.5can be used in drug delivery research .
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- HY-166850
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Biochemical Assay Reagents
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Others
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DOPE-PEG5000-Cy5.5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-Cy5.5can be used in drug delivery research .
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- HY-170455
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Biochemical Assay Reagents
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Others
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18:1 PE (DOPE) pSar25 is a derivative of polyethylene glycol that can be used for liposomal and lipid nanoparticle delivery systems.
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- HY-W440991
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DOPE-PEG2000-NH2
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Liposome
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Cancer
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DOPE-PEG-Amine (MW 2000) is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form a triazole ring.
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- HY-W1130458
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Liposome
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Inflammation/Immunology
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503O8,12 is an ionizable cationic lipidoid that enables mRNA delivery to the spleen and lungs in mice when formulated into lipid nanoparticles with neutral helper lipid DOPE[1].
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- HY-112005S
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Dioleoylphosphatidylethanolamine-d62; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-d62
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Isotope-Labeled Compounds
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Inflammation/Immunology
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DOPE-d62 (Dioleoylphosphatidylethanolamine-d62) is the deuterium labeled DOPE (HY-112005). DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
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- HY-W440988D
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Biochemical Assay Reagents
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Others
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DOPE-mPEG750 is a PEGylated phospholipid containing DOPE. DOPE-mPEG750 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.
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- HY-W440988E
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Biochemical Assay Reagents
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Others
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DOPE-mPEG10000 is a PEGylated phospholipid containing DOPE. DOPE-mPEG10000 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.
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- HY-W440988H
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Biochemical Assay Reagents
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Others
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DOPE-mPEG20000 is a PEGylated phospholipid containing DOPE. DOPE-mPEG20000 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.
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- HY-W440988I
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Biochemical Assay Reagents
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Others
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DOPE-mPEG30000 is a PEGylated phospholipid containing DOPE. DOPE-mPEG30000 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.
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- HY-W440988A
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Biochemical Assay Reagents
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Others
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DOPE-mPEG350 is a PEGylated phospholipid containing DOPE. DOPE-mPEG350 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.
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- HY-W440988B
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Biochemical Assay Reagents
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Others
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DOPE-mPEG500 is a PEGylated phospholipid containing DOPE. DOPE-mPEG500 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.
|
-
- HY-W440988C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-mPEG550 is a PEGylated phospholipid containing DOPE. DOPE-mPEG550 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.
|
-
- HY-W1053112B
-
|
DOPE-PEG10000-NH2
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG10000-Amine (DOPE-PEG1000-NH2) is a conjugate composed of dioleoylphosphatidylethanolamine (DOPE), a PEG chain, and a terminal amino group (-NH2). The amino group in DOPE-PEG10000-Amine can chemically react with carboxyl groups, activated esters, etc., participating in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.
|
-
- HY-W440990
-
|
DOPE-PEG1000-NH2
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG1000-Amine (DOPE-PEG1000-NH2) is a conjugate composed of dioleoylphosphatidylethanolamine (DOPE), a PEG chain, and a terminal amino group (-NH2). The amino group in DOPE-PEG1000-Amine can chemically react with carboxyl groups, activated esters, etc., participating in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.
|
-
- HY-112005G
-
|
Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
|
Ferroptosis
Glutathione Peroxidase
ACSL Family
Amino acid Transporter
|
Neurological Disease
Inflammation/Immunology
|
|
DOPE GMP is DOPE (HY-112005) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE (Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) is an orally active inhibitor of ferroptosis with anti-inflammatory and intestinal barrier maintenance activities. DOPE regulates the expression of ACSL4, SLC7A11 and GPX4 to restore the redox system balance, thereby reducing the levels of lipid peroxides, iron ions and intestinal inflammatory factors (IL-1β and IL-6). DOPE promotes the migration and proliferation of intestinal epithelial cells and increases the level of tight junction proteins; it also destabilizes endosomal membranes, mediates the conjugation of RVG peptides with mesenchymal stem cell-derived exosomes to enhance brain targeting. DOPE can be applied to research related to neonatal necrotizing enterocolitis and Alzheimer's disease .
|
-
- HY-203300D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG1000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
|
-
- HY-203300C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG5000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
|
-
- HY-203300B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG3400-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
|
-
- HY-203300A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG1000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
|
-
- HY-203300
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG2000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
|
-
- HY-W440989
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-mPEG5000 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-mPEG5000can be used in drug delivery research .
|
-
- HY-W440828
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG3400-COOH is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG3400-COOHcan be used in drug delivery research .
|
-
- HY-W440993
-
|
DOPE-PEG5000-NH2
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG-Amine (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Amine (MW 5000)can be used in drug delivery research .
|
-
- HY-W591451
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG5000-Azide is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-Azidecan be used in drug delivery research .
|
-
- HY-W440992
-
|
DOPE-PEG3400-NH2
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG-Amine (MW 3400) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Amine (MW 3400)can be used in drug delivery research .
|
-
- HY-W440826
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG1000-COOH is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG1000-COOHcan be used in drug delivery research .
|
-
- HY-W440829
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG5000-COOH is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-COOHcan be used in drug delivery research .
|
-
- HY-166680
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOPE-PEG5000-FITC is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-FITCcan be used in drug delivery research .
|
-
- HY-179836
-
|
|
Liposome
|
Metabolic Disease
|
|
DOPE-PEG-Azide ammonium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
|
-
- HY-174972I
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG20000-DPPE is a PEGylated phospholipid containing DPPE. DOPE-mPEG750 combines the membrane fusion capability of DPPE with the stealth properties of PEG, and can be used for applications such as constructing targeted drug delivery systems and liposome preparation.
|
-
- HY-141613S
-
|
(2S,8R,19Z)DOPS-d3 ammonium
|
Isotope-Labeled Compounds
|
Others
|
|
(2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine-d3 ammonium ((2S,8R,19Z)DOPS-d3 ammonium) is the deuterium labeled (2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine ammonium (HY-141613). 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) is a ubstitute for Phosphoserine/phosphatidylserine. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can be used together with DOPC and DOPE in lipid mixtures for the synthesis of liposomes. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can self-assemble into single-layer or double-layer membrane structures, similar to cell membranes, and possesses high membrane fluidity and flexibility. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine is widely applied in membrane biology, cell membrane research, lipid preparation, and drug delivery systems .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D0948
-
|
|
Fluorescent Dyes
|
|
Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO2 nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen .
|
-
- HY-112005GL
-
|
Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)
|
Fluorescent Dyes
|
|
DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
|
-
- HY-112005G
-
|
Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
|
Fluorescent Dyes
|
|
DOPE GMP is DOPE (HY-112005) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE (Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) is an orally active inhibitor of ferroptosis with anti-inflammatory and intestinal barrier maintenance activities. DOPE regulates the expression of ACSL4, SLC7A11 and GPX4 to restore the redox system balance, thereby reducing the levels of lipid peroxides, iron ions and intestinal inflammatory factors (IL-1β and IL-6). DOPE promotes the migration and proliferation of intestinal epithelial cells and increases the level of tight junction proteins; it also destabilizes endosomal membranes, mediates the conjugation of RVG peptides with mesenchymal stem cell-derived exosomes to enhance brain targeting. DOPE can be applied to research related to neonatal necrotizing enterocolitis and Alzheimer's disease .
|
| Cat. No. |
Product Name |
Type |
-
- HY-112005
-
|
Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
|
Biochemical Assay Reagents
|
|
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
|
-
- HY-141613
-
|
DOPS-NA
|
Biochemical Assay Reagents
|
|
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) is a ubstitute for Phosphoserine/phosphatidylserine. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can be used together with DOPC and DOPE in lipid mixtures for the synthesis of liposomes. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can self-assemble into single-layer or double-layer membrane structures, similar to cell membranes, and possesses high membrane fluidity and flexibility. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine is widely applied in membrane biology, cell membrane research, lipid preparation, and drug delivery systems .
|
-
- HY-150241
-
|
|
Biochemical Assay Reagents
|
|
DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .
|
-
- HY-144010
-
|
DOPE-PEG2000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
|
Biochemical Assay Reagents
|
|
18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) can be used for drug delivery .
|
-
- HY-142997
-
|
|
Biochemical Assay Reagents
|
|
DOSPA is a cationic lipid. DOSPA can form lipid nanoparticles with DOPE (HY-112005) to serve as a carrier for nucleic acid transfection. DOSPA is applicable in research related to drug delivery .
|
-
- HY-W440988
-
|
|
Biochemical Assay Reagents
|
|
DOPE-mPEG2000 is a phospholipid polydisperse PEG (or DOPE liposome), can be used for preparation of targeted delivery of liposomal drug and giant unilamellar vesicles (GUVs). DOPE-mPEG2000 significantly reduces the pH-sensitivity of the liposome in a concentration dependent manner .
|
-
- HY-164035
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-DBCO is a PEG lipid with a DOPE and a DBCO as functional groups. DOPE can be used as a helper lipid in gene transfection. PEG is used in drug delivery system. DBCO can be used for click chemistry .
|
-
- HY-166883
-
-
- HY-21170B
-
|
Triflate lithium; Trifluoromethylsulfonate lithium; Trifluoromethanesulphonic acid lithium
|
Biochemical Assay Reagents
|
|
Trifluoromethanesulfonate (Triflate;Trifluoromethylsulfonate) lithium is a stable lithium salt and dopant with four resonance states, which is commonly used as an electrolyte component in polymer light-emitting electrochemical cells and primary lithium batteries. Trifluoromethanesulfonate lithiumalso acts as a catalyst for the preparation of the herbicide Imazapyr. In MEH-PPV-based light-emitting electrochemical cells, Trifluoromethanesulfonate lithium promotes electrochemical p-type doping at the anode interface under applied bias, thereby facilitating the formation of p-i-n junctions, exciton generation, and light emission. Trifluoromethanesulfonate lithiumexhibits strong ion pairing in non-aqueous electrolytes, but its electrochemical stability window is narrower than that of lithium bistrifluoromethylsulfonyl imidee .
|
-
- HY-137499
-
|
|
Biochemical Assay Reagents
|
|
NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .
|
-
- HY-W440987
-
|
|
Biochemical Assay Reagents
|
|
DOPE-mPEG1000 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations to achieve better therapeutic effects. DOPE-mPEG1000 can be used in drug delivery research .
|
-
- HY-160272
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-Fluor 488 is a PEG lipid, composed of a DOPE phospholipid and a Fluor 488 fluorophore. DOPE is an unsaturated phospholipid. Fluor 488 has excitation and emission maxima at 499 nm and 520 nm .
|
-
- HY-160280
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-Fluor 647 is a PEG-lipid-dye conjugate. composed of a DOPE phospholipid and a Fluor 647 dye .
|
-
- HY-112005GL
-
|
Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)
|
Biochemical Assay Reagents
|
|
DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
|
-
- HY-W591450
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG3400-Azide is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG3400-Azidecan be used in drug delivery research .
|
-
- HY-W591448
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG1000-Azide is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG1000-Azidecan be used in drug delivery research .
|
-
- HY-150240
-
|
|
Biochemical Assay Reagents
|
|
DOPE-GA can be used in the preparation of liposomes for research on drug delivery and other applications .
|
-
- HY-155934
-
|
DOPE-PEG5000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Biochemical Assay Reagents
|
|
18:1 PEG5000 PE ammonium (DOPE-PEG5000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-160273
-
-
- HY-W440996
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG3400-Mal is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG3400-Malcan be used in drug delivery research .
|
-
- HY-166852
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-Cy5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-Cy5can be used in drug delivery research .
|
-
- HY-155931
-
|
DOPE-PEG550 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Biochemical Assay Reagents
|
|
18:1 PEG550 PE ammonium (DOPE-PEG550 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155933
-
|
DOPE-PEG3000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Biochemical Assay Reagents
|
|
18:1 PEG3000 PE ammonium (DOPE-PEG3000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155932
-
|
DOPE-PEG1000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Biochemical Assay Reagents
|
|
18:1 PEG1000 PE ammonium (DOPE-PEG1000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155930
-
|
DOPE-PEG350 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Biochemical Assay Reagents
|
|
18:1 PEG350 PE ammonium (DOPE-PEG350 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-160275
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-Fluor 555 is a PEG-lipid-dye conjugate featuring a DOPE phospholipid and a Fluor 555 dye. DOPE (HY-112005) is a neutral helper lipid for cationic liposome. Fluor 555 is a fluorescent dye .
|
-
- HY-167031
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG5000-DBCO is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DOPE-PEG5000-DBCO can be used in drug delivery research .
|
-
- HY-160276
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG5000-Fluor 555 is consist of a DOPE phospholipid which is an unsaturated phospholipid and a Fluor 555 dye which is a bright orange cyanine dye that can be used in fluorescence microscopy, FRET and other in vivo imaging techniques.
|
-
- HY-173383
-
|
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N- tetraazacyclododecane-N-tetraacetic acid, sodium salt
|
Biochemical Assay Reagents
|
|
DOPE-DOTA sodium is a chelated lipid that serves as a key contrast agent in magnetic resonance imaging (MRI). DOPE-DOTA sodium can be used for cancer, blood-brain barrier disruption, abnormalities such as aneurysms or plaque buildup, inflammation in arthritis, and liver function and lesions study
|
-
- HY-W440997
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG5000-Mal is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-Malcan be used in drug delivery research .
|
-
- HY-166846
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-FITC is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-FITCcan be used in drug delivery research .
|
-
- HY-166833
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG5000-Rhodamine B is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-Rhodamine Bcan be used in drug delivery research .
|
-
- HY-166849
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG5000-Cy5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-Cy5can be used in drug delivery research .
|
-
- HY-166848
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-Cy5.5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-Cy5.5can be used in drug delivery research .
|
-
- HY-166850
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG5000-Cy5.5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-Cy5.5can be used in drug delivery research .
|
-
- HY-170455
-
|
|
Biochemical Assay Reagents
|
|
18:1 PE (DOPE) pSar25 is a derivative of polyethylene glycol that can be used for liposomal and lipid nanoparticle delivery systems.
|
-
- HY-W440988D
-
|
|
Biochemical Assay Reagents
|
|
DOPE-mPEG750 is a PEGylated phospholipid containing DOPE. DOPE-mPEG750 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.
|
-
- HY-W440988E
-
|
|
Biochemical Assay Reagents
|
|
DOPE-mPEG10000 is a PEGylated phospholipid containing DOPE. DOPE-mPEG10000 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.
|
-
- HY-W440988H
-
|
|
Biochemical Assay Reagents
|
|
DOPE-mPEG20000 is a PEGylated phospholipid containing DOPE. DOPE-mPEG20000 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.
|
-
- HY-W440988I
-
|
|
Biochemical Assay Reagents
|
|
DOPE-mPEG30000 is a PEGylated phospholipid containing DOPE. DOPE-mPEG30000 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.
|
-
- HY-W440988A
-
|
|
Biochemical Assay Reagents
|
|
DOPE-mPEG350 is a PEGylated phospholipid containing DOPE. DOPE-mPEG350 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.
|
-
- HY-W440988B
-
|
|
Biochemical Assay Reagents
|
|
DOPE-mPEG500 is a PEGylated phospholipid containing DOPE. DOPE-mPEG500 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.
|
-
- HY-W440988C
-
|
|
Biochemical Assay Reagents
|
|
DOPE-mPEG550 is a PEGylated phospholipid containing DOPE. DOPE-mPEG550 combines the membrane fusion capabilities of DOPE with the stealth properties of PEG, playing a crucial role in mRNA vaccines, long-circulating liposomes, and drug delivery systems.
|
-
- HY-W1053112B
-
|
DOPE-PEG10000-NH2
|
Biochemical Assay Reagents
|
|
DOPE-PEG10000-Amine (DOPE-PEG1000-NH2) is a conjugate composed of dioleoylphosphatidylethanolamine (DOPE), a PEG chain, and a terminal amino group (-NH2). The amino group in DOPE-PEG10000-Amine can chemically react with carboxyl groups, activated esters, etc., participating in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.
|
-
- HY-W440990
-
|
DOPE-PEG1000-NH2
|
Biochemical Assay Reagents
|
|
DOPE-PEG1000-Amine (DOPE-PEG1000-NH2) is a conjugate composed of dioleoylphosphatidylethanolamine (DOPE), a PEG chain, and a terminal amino group (-NH2). The amino group in DOPE-PEG1000-Amine can chemically react with carboxyl groups, activated esters, etc., participating in various bioconjugation reactions for targeted modification of liposomes/nanoparticles.
|
-
- HY-112005G
-
|
Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
|
Biochemical Assay Reagents
|
|
DOPE GMP is DOPE (HY-112005) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE (Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) is an orally active inhibitor of ferroptosis with anti-inflammatory and intestinal barrier maintenance activities. DOPE regulates the expression of ACSL4, SLC7A11 and GPX4 to restore the redox system balance, thereby reducing the levels of lipid peroxides, iron ions and intestinal inflammatory factors (IL-1β and IL-6). DOPE promotes the migration and proliferation of intestinal epithelial cells and increases the level of tight junction proteins; it also destabilizes endosomal membranes, mediates the conjugation of RVG peptides with mesenchymal stem cell-derived exosomes to enhance brain targeting. DOPE can be applied to research related to neonatal necrotizing enterocolitis and Alzheimer's disease .
|
-
- HY-203300D
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG1000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
|
-
- HY-203300C
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG5000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG5000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
|
-
- HY-203300B
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG3400-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG3400-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
|
-
- HY-203300A
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG1000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG1000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
|
- HY-203300
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG2000-NHS is a conjugate composed of DOPE, PEG chains, and terminal active ester (NHS). The NHS ester in DOPE-PEG2000-NHS can rapidly covalently react with molecules containing primary amines (such as proteins, peptide chains, and small molecules modified with amino groups) to form stable amide bonds, suitable for the construction of carriers requiring membrane fusion properties or pH-sensitive release (such as gene delivery systems).
|
- HY-W440989
-
|
|
Biochemical Assay Reagents
|
|
DOPE-mPEG5000 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-mPEG5000can be used in drug delivery research .
|
- HY-W440828
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG3400-COOH is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG3400-COOHcan be used in drug delivery research .
|
- HY-W440993
-
|
DOPE-PEG5000-NH2
|
Biochemical Assay Reagents
|
|
DOPE-PEG-Amine (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Amine (MW 5000)can be used in drug delivery research .
|
- HY-W591451
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG5000-Azide is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-Azidecan be used in drug delivery research .
|
- HY-W440992
-
|
DOPE-PEG3400-NH2
|
Biochemical Assay Reagents
|
|
DOPE-PEG-Amine (MW 3400) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Amine (MW 3400)can be used in drug delivery research .
|
- HY-W440826
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG1000-COOH is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG1000-COOHcan be used in drug delivery research .
|
- HY-W440829
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG5000-COOH is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-COOHcan be used in drug delivery research .
|
- HY-166680
-
|
|
Biochemical Assay Reagents
|
|
DOPE-PEG5000-FITC is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-FITCcan be used in drug delivery research .
|
- HY-174972I
-
|
|
Biochemical Assay Reagents
|
|
mPEG20000-DPPE is a PEGylated phospholipid containing DPPE. DOPE-mPEG750 combines the membrane fusion capability of DPPE with the stealth properties of PEG, and can be used for applications such as constructing targeted drug delivery systems and liposome preparation.
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-121252
-
-
-
- HY-N16025
-
|
|
Structural Classification
Lipid
|
Liposome
Biochemical Assay Reagents
|
|
DOPE-PEG(2000) Amine ammonium is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted agent delivery and is reactive with alkyne to form a triazole ring .
|
-
-
- HY-N12762
-
-
-
- HY-137499
-
-
-
- HY-N15907
-
|
|
Structural Classification
Lipid
|
Liposome
|
|
DOPE PEG(2000)-N-Cyanine 5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE PEG(2000)-N-Cyanine 5 can be used in drug delivery research.
|
-
-
- HY-N15803
-
|
|
Lipid
|
Biochemical Assay Reagents
|
|
DOPE-RGD Lipid sodium is a lipid containing DOPE and RGD peptides that can be used to prepare lipid nanoparticles for drug delivery.
|
-
-
- HY-N16036
-
|
|
Lipid
|
Biochemical Assay Reagents
|
|
DOPE-PEG(2000)-HALO-TAG ammonium is a PEG polymer containing unsaturated DOPE phospholipids. DOPE-PEG(2000)-HALO-TAG ammonium can be used to prepare liposomes or other nanoparticles for drug delivery.
|
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-121252S
-
|
|
|
Dopal-d5 is the deuterium labeled Dopal (HY-121252). Dopal is a metabolite and aldehyde neurotoxin of Dopamine (HY-B0451). Dopal exhibits cytotoxicity, induces α-synuclein oligomerization and aggregation, and is closely associated with the pathogenesis of Parkinson's disease. Dopal can be used in research related to Parkinson's disease .
|
-
-
- HY-112005S
-
|
|
|
DOPE-d62 (Dioleoylphosphatidylethanolamine-d62) is the deuterium labeled DOPE (HY-112005). DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
|
-
-
- HY-141613S
-
|
|
|
(2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine-d3 ammonium ((2S,8R,19Z)DOPS-d3 ammonium) is the deuterium labeled (2S,8R,19Z)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine ammonium (HY-141613). 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) is a ubstitute for Phosphoserine/phosphatidylserine. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can be used together with DOPC and DOPE in lipid mixtures for the synthesis of liposomes. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can self-assemble into single-layer or double-layer membrane structures, similar to cell membranes, and possesses high membrane fluidity and flexibility. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine is widely applied in membrane biology, cell membrane research, lipid preparation, and drug delivery systems .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-164035
-
|
|
|
DBCO
|
|
DOPE-PEG2000-DBCO is a PEG lipid with a DOPE and a DBCO as functional groups. DOPE can be used as a helper lipid in gene transfection. PEG is used in drug delivery system. DBCO can be used for click chemistry .
|
-
- HY-167031
-
|
|
|
DBCO
|
|
DOPE-PEG5000-DBCO is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DOPE-PEG5000-DBCO can be used in drug delivery research .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-112005
-
|
Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
|
|
Phospholipids
|
|
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
|
-
- HY-141613
-
|
DOPS-NA
|
|
Phospholipids
|
|
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) is a ubstitute for Phosphoserine/phosphatidylserine. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can be used together with DOPC and DOPE in lipid mixtures for the synthesis of liposomes. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can self-assemble into single-layer or double-layer membrane structures, similar to cell membranes, and possesses high membrane fluidity and flexibility. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine is widely applied in membrane biology, cell membrane research, lipid preparation, and drug delivery systems .
|
-
- HY-150241
-
|
|
|
Phospholipids
|
|
DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .
|
-
- HY-144010
-
|
DOPE-PEG2000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
|
|
Pegylated Lipids
|
|
18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) can be used for drug delivery .
|
-
- HY-142997
-
|
|
|
Cationic Lipids
|
|
DOSPA is a cationic lipid. DOSPA can form lipid nanoparticles with DOPE (HY-112005) to serve as a carrier for nucleic acid transfection. DOSPA is applicable in research related to drug delivery .
|
-
- HY-W440988
-
|
|
|
Pegylated Lipids
|
|
DOPE-mPEG2000 is a phospholipid polydisperse PEG (or DOPE liposome), can be used for preparation of targeted delivery of liposomal drug and giant unilamellar vesicles (GUVs). DOPE-mPEG2000 significantly reduces the pH-sensitivity of the liposome in a concentration dependent manner .
|
-
- HY-W440827
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG2000-COOH is a PEG polymer containing unsaturated DOPE phospholipids and carboxylic acids. DOPE-PEG2000-COOH can be used to prepare liposomes or other nanoparticles for drug delivery .
|
-
- HY-164035
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG2000-DBCO is a PEG lipid with a DOPE and a DBCO as functional groups. DOPE can be used as a helper lipid in gene transfection. PEG is used in drug delivery system. DBCO can be used for click chemistry .
|
-
- HY-166883
-
-
- HY-N12762
-
|
|
|
Cationic Lipids
|
|
DGTS, as described, is a structural isomer of DGTA and one of the most common betaine lipids found in microalgae, particularly abundant in Chlorophyceae . DGTS is a helper lipid that is structurally similar to DSPE or DOPE.
|
-
- HY-137499
-
|
|
|
Cationic Lipids
|
|
NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .
|
-
- HY-W440995
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG2000-Mal is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. It is also reactive with thiol at pH 6.5 tp 7.5 to form a stable thioether bond.
|
-
- HY-160272
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DOPE-PEG2000-Fluor 488 is a PEG lipid, composed of a DOPE phospholipid and a Fluor 488 fluorophore. DOPE is an unsaturated phospholipid. Fluor 488 has excitation and emission maxima at 499 nm and 520 nm .
|
-
- HY-160280
-
-
- HY-N15995
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG(2000) Carboxylic acid sodium is a stabilizer. DOPE-PEG(2000) Carboxylic acid sodium produce a coating around the ferrofluid droplet chains which are dispersed in 5CB. DOPE-PEG(2000) Carboxylic acid sodium tends to fold, effectively shielding the surrounding LC molecules from the homeotropic anchoring at the droplet interface and leading to smaller deformations and thus also creating a more stable interface .
|
-
- HY-W591450
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG3400-Azide is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG3400-Azidecan be used in drug delivery research .
|
-
- HY-W591448
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG1000-Azide is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG1000-Azidecan be used in drug delivery research .
|
-
- HY-155934
-
|
DOPE-PEG5000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
|
Pegylated Lipids
|
|
18:1 PEG5000 PE ammonium (DOPE-PEG5000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-175410
-
|
1,2-Dioloeoyl-sn-glycero-3-phosphoethanolamine-C8; 1,2-DOPE-C8
|
|
Cationic Lipids
|
|
DOPE-C8 (1,2-Dioloeoyl-sn-glycero-3-phosphoethanolamine-C8; 1,2-DOPE-C8) is a zwitterionic phospholipid derived from DOPE that has been used to generate lipid nanoparticles (LNPs) for in vivo delivery of mRNA .
|
-
- HY-160273
-
-
- HY-W440996
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG3400-Mal is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG3400-Malcan be used in drug delivery research .
|
-
- HY-166852
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DOPE-PEG2000-Cy5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-Cy5can be used in drug delivery research .
|
-
- HY-129990
-
|
|
|
Cationic Lipids
|
|
Dios-Arg diTFA, a cationic lipid with an arginine-bearing headgroup, shows obvious double bond proton signals at around 5.2-5.3 ppm. Dios-Arg diTFA is used, coupled to DOPE, to bind siRNA and plasmid to for cationic LNPs for intracellular transport .
|
-
- HY-158705
-
|
|
|
Cationic Lipids
|
|
SAINT-2 is a cationic lipid with gene transfection activity and is a pyridyl lipid analog. Molecular membranes prepared by SAINT-2 can interact with plasmids to form lipid complexes. After the complex is taken up by cells, the plasmid dissociates from the lipid complex under the action of DOPE and the plasmid translocates across the endosome and/or nuclear membrane. Thus, SAINT-2 effectively transfers small oligonucleotides into cells .
|
-
- HY-W591449
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG2000-Azide is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
|
-
- HY-155931
-
|
DOPE-PEG550 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
|
Pegylated Lipids
|
|
18:1 PEG550 PE ammonium (DOPE-PEG550 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155933
-
|
DOPE-PEG3000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
|
Pegylated Lipids
|
|
18:1 PEG3000 PE ammonium (DOPE-PEG3000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155932
-
|
DOPE-PEG1000 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
|
Pegylated Lipids
|
|
18:1 PEG1000 PE ammonium (DOPE-PEG1000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155930
-
|
DOPE-PEG350 ammonium; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
|
Pegylated Lipids
|
|
18:1 PEG350 PE ammonium (DOPE-PEG350 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-160275
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DOPE-PEG2000-Fluor 555 is a PEG-lipid-dye conjugate featuring a DOPE phospholipid and a Fluor 555 dye. DOPE (HY-112005) is a neutral helper lipid for cationic liposome. Fluor 555 is a fluorescent dye .
|
-
- HY-160573
-
|
|
|
Cationic Lipids
|
|
cKK-E15 is a peptide-lipid that can be used to formulate LNP3 with C14PEG2000, unmodified cholesterol, and DOPE .
|
-
- HY-167031
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG5000-DBCO is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DOPE-PEG5000-DBCO can be used in drug delivery research .
|
-
- HY-160276
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DOPE-PEG5000-Fluor 555 is consist of a DOPE phospholipid which is an unsaturated phospholipid and a Fluor 555 dye which is a bright orange cyanine dye that can be used in fluorescence microscopy, FRET and other in vivo imaging techniques.
|
-
- HY-W440997
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG5000-Mal is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-Malcan be used in drug delivery research .
|
-
- HY-166846
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DOPE-PEG2000-FITC is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-FITCcan be used in drug delivery research .
|
-
- HY-166833
-
|
|
|
Pegylated Lipids
|
|
DOPE-PEG5000-Rhodamine B is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-Rhodamine Bcan be used in drug delivery research .
|
-
- HY-166849
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
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DOPE-PEG5000-Cy5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-Cy5can be used in drug delivery research .
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- HY-166848
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Pegylated Lipids
Fluorescent Lipids
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DOPE-PEG2000-Cy5.5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG2000-Cy5.5can be used in drug delivery research .
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- HY-166850
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Pegylated Lipids
Fluorescent Lipids
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DOPE-PEG5000-Cy5.5 is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-Cy5.5can be used in drug delivery research .
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- HY-W440991
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DOPE-PEG2000-NH2
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Pegylated Lipids
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DOPE-PEG-Amine (MW 2000) is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form a triazole ring.
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- HY-W440828
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Pegylated Lipids
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DOPE-PEG3400-COOH is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG3400-COOHcan be used in drug delivery research .
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- HY-W440993
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DOPE-PEG5000-NH2
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Pegylated Lipids
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DOPE-PEG-Amine (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Amine (MW 5000)can be used in drug delivery research .
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- HY-W591451
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Pegylated Lipids
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DOPE-PEG5000-Azide is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-Azidecan be used in drug delivery research .
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- HY-W440992
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DOPE-PEG3400-NH2
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Pegylated Lipids
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DOPE-PEG-Amine (MW 3400) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Amine (MW 3400)can be used in drug delivery research .
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- HY-W440826
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Pegylated Lipids
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DOPE-PEG1000-COOH is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG1000-COOHcan be used in drug delivery research .
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- HY-W440829
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Pegylated Lipids
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DOPE-PEG5000-COOH is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-COOHcan be used in drug delivery research .
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- HY-166680
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Pegylated Lipids
Fluorescent Lipids
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DOPE-PEG5000-FITC is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG5000-FITCcan be used in drug delivery research .
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- HY-179836
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Pegylated Lipids
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DOPE-PEG-Azide ammonium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery.
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| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-112005GL
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Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)
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Liposome
Endogenous Metabolite
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Inflammation/Immunology
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DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
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- HY-112005G
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Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
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Ferroptosis
Glutathione Peroxidase
ACSL Family
Amino acid Transporter
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Neurological Disease
Inflammation/Immunology
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DOPE GMP is DOPE (HY-112005) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE (Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) is an orally active inhibitor of ferroptosis with anti-inflammatory and intestinal barrier maintenance activities. DOPE regulates the expression of ACSL4, SLC7A11 and GPX4 to restore the redox system balance, thereby reducing the levels of lipid peroxides, iron ions and intestinal inflammatory factors (IL-1β and IL-6). DOPE promotes the migration and proliferation of intestinal epithelial cells and increases the level of tight junction proteins; it also destabilizes endosomal membranes, mediates the conjugation of RVG peptides with mesenchymal stem cell-derived exosomes to enhance brain targeting. DOPE can be applied to research related to neonatal necrotizing enterocolitis and Alzheimer's disease .
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