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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
embryotoxicity
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "embryotoxicity" in MCE Product Catalog:
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Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor .
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1 Cited Publications
Synonyms: Manganese(Ⅱ) chloride tetrahydrate, molecular biology grade,≥99.0% (KT)
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1 Cited Publications
Fluopyram is an orally active succinate dehydrogenase inhibitor, antifungal and nematicide. Fluopyram inhibits succinate dehydrogenase activity, activates CAR/PXR nuclear receptors, and increases caspase-3, TNF-α and NF-κB. Fluopyram inhibits the growth of F. virguliforme, Botrytis cinerea and Alternaria solani with EC50 values of 3.35, 5.389 and 0.244 µg/mL, respectively. Fluopyram induces liver and thyroid tumor formation. Fluopyram is nephrotoxic and embryotoxic .
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Dibenzothiophene is an orally active and a noncompetitive CYP1A inhibitor. Dibenzothiophene inhibits CYP1A-mediated EROD activity with a Km of 0.592 μM. Dibenzothiophene interacts with the AHR pathway. Dibenzothiophene enhances the embryotoxicity of β-naphthoflavone (HY-114740). Dibenzothiophene shows acute toxicity in mice. Dibenzothiophene is mainly used for the study of the mechanism of developmental toxicity in organisms .
Cat. No.: HY-W040194
CAS No.: 81777-89-1
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Clomazone is a broad spectrum herbicide, mainly used to control annual broadleaf weeds and grass weeds in various crops such as rice, soybeans, and peanuts. Clomazone inhibits carotenoid biosynthesis, and treated plants show typical "albinism" symptoms due to the destruction of chloroplast membrane structure leading to chlorophyll degradation. Clomazone exhibits multiple toxic effects on non-target organisms, including aquatic lethality, developmental malformations, liver damage, mitochondrial dysfunction, and hematotoxicity .
Synonyms: stearyldimethylbenzylammonium chloride; Benzyldimethyloctadecylammonium chloride
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Benzyldimethylstearylammonium chloride is a quaternary ammonium cationic surfactant without embryotoxicity .
Cat. No.: HY-N8492
CAS No.: 13283-90-4
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Cat. No.: HY-119459R
CAS No.: 658066-35-4
Fluopyram (Standard) is the analytical standard of Fluopyram (HY-119459). This product is intended for research and analytical applications. Fluopyram is an orally active succinate dehydrogenase inhibitor, antifungal and nematicide. Fluopyram inhibits succinate dehydrogenase activity, activates CAR/PXR nuclear receptors, and increases caspase-3, TNF-α and NF-κB. Fluopyram inhibits the growth of F. virguliforme, Botrytis cinerea and Alternaria solani with EC50 values of 3.35, 5.389 and 0.244 µg/mL, respectively. Fluopyram induces liver and thyroid tumor formation. Fluopyram is nephrotoxic and embryotoxic .
Cat. No.: HY-19141
CAS No.: 136075-60-0
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L-691121 exhibits antiarrhythmic efficacy through block of potassium channel and a followed prolonged cardiac potential. L-691121 exhibits embryotoxicity with fetal mortality at the dose of 0.8 mg/kg/day (p.o.). L-691121 is orally active .
Cat. No.: HY-B0806AR
CAS No.: 637-32-1
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Proguanil (hydrochloride) (Standard) is the analytical standard of Proguanil (hydrochloride). This product is intended for research and analytical applications. Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor .
Target:
Research Areas:
Proguanil (Standard) is the analytical standard of Proguanil. This product is intended for research and analytical applications. Proguanil, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil is a dihydrofolate reductase (DHFR) inhibitor .
Cat. No.: HY-W011777S
Synonyms: MS-222-d5
Cat. No.: HY-B0973S
CAS No.: 33262-29-2
Research Areas:
Dibenzothiophene (Standard) is the analytical standard of Dibenzothiophene (HY-B0973). This product is intended for research and analytical applications. Dibenzothiophene is an orally active and a noncompetitive CYP1A inhibitor. Dibenzothiophene inhibits CYP1A-mediated EROD activity with Km of 0.592 μM. Dibenzothiophene interacts with the AHR pathway. Dibenzothiophene enhances the embryotoxicity of β-naphthoflavone (HY-114740). Dibenzothiophene shows acute toxicity in mice. Dibenzothiophene is mainly used for the study of the mechanism of developmental toxicity in organisms .
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Research Areas:
DCPD is an amine substance with both embryotoxicity and teratogenicity, and its total effect ED50 is 0.6 μmol per egg. DCPD induces early and late embryonic death, and causes multiple embryonic malformations including microcephaly, hypoplastic optic cup, eyelid and corneal defects. DCPD can serve as a calcium phosphate additive for biomimetic α-tricalcium phosphate bone cement, which inhibits the transformation of α-tricalcium phosphate into calcium-deficient hydroxyapatite, blocks the release of Gelatins (HY-Y1365), and effectively prolongs the setting time of bone cement. DCPD is applicable to studies related to embryonic malformations .\n
Cat. No.: HY-19659A
CAS No.: 164150-85-0
Synonyms: DW-116 hydrochloride
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Fandofloxacin (DW-116) hydrochloride is an orally active quinolone antibiotic. Fandofloxacin hydrochloride is embryotoxic and teratogenic. Fandofloxacin hydrochloride can be used for the research of bacterial infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
