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haemoglobin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (1) Apoptosis (1) Biochemical Assay Reagents (1) CHIKV (1) Dengue Virus (1) Endogenous Metabolite (1) Flavivirus (1) Hemoglobin (3) Isotope-Labeled Compounds (5) Parasite (1) Reactive Oxygen Species (ROS) (2) Reference Standards (5) TrxR (1)
By Research Areas:	Cancer (7) Cardiovascular Disease (7) Infection (4) Metabolic Disease (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-18681

Voxelotor Maximum Cited Publications 9 Publications Verification GBT 440	Hemoglobin	Cardiovascular Disease
Voxelotor (GBT 440) is a potent inhibitor of haemoglobin S (HbS) polymerization. Voxelotor has the potential for sickle cell disease (SCD) treatment .

HY-13619

Efaproxiral 1 Publications Verification RSR13	Hemoglobin	Infection Cancer
Efaproxiral (RSR13) is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .

HY-13619A

Efaproxiral sodium 1 Publications Verification RSR13 sodium	Hemoglobin	Infection Cancer
Efaproxiral (RSR13) sodium is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral sodium decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .

HY-135514

Lys-Phe H-Lys-Phe-OH	Amino Acid Derivatives	Cardiovascular Disease
Lys-Phe is a dipeptide that inhibits both cell sickling and the gelation of solutions of sickle-cell haemoglobin .

HY-101193R

Zinc Protoporphyrin (Standard) Zn(II)-protoporphyrin IX (Standard); ZnPP (Standard); Zinc Protoporphyrin-9 (Standard)	Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis	Cardiovascular Disease Metabolic Disease Cancer
Zinc Protoporphyrin (Standard) is the analytical standard of Zinc Protoporphyrin. This product is intended for research and analytical applications. Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2 . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .

HY-P2995A

Hemoglobin porcine	Biochemical Assay Reagents	Others
Hemoglobin porcine is an oxygen-transporting protein present in the blood of domestic pigs, and also an oxygen carrier with higher oxygen affinity than human hemoglobin. Hemoglobin porcine exhibits cooperative oxygen-binding properties, with weaker heme-heme interactions than those of human hemoglobin .

HY-18681R

Voxelotor (Standard) GBT 440 (Standard)	Others Reference Standards	Cardiovascular Disease
Voxelotor (Standard) is the analytical standard of Voxelotor. This product is intended for research and analytical applications. Voxelotor (GBT 440) is a potent inhibitor of haemoglobin S (HbS) polymerization. Voxelotor has the potential for sickle cell disease (SCD) treatment .

HY-W728761

Voxelotor-d7 GBT 440-d₇	Isotope-Labeled Compounds	Cardiovascular Disease
Voxelotor-d7 is the deuterium labeled Voxelotor (HY-18681). Voxelotor is a potent inhibitor of haemoglobin S (HbS) polymerization .

HY-18681S

Voxelotor-d6 GBT 440-d₆	Isotope-Labeled Compounds Others	Cardiovascular Disease
Voxelotor-d₆ (GBT 440-d₆) is deuterium labeled Voxelotor. Voxelotor (GBT 440) is a potent inhibitor of haemoglobin S (HbS) polymerization. Voxelotor has the potential for sickle cell disease (SCD) treatment .

HY-13619S

Efaproxiral-d6 RSR13-d₆	Isotope-Labeled Compounds	Cancer
Efaproxiral (RSR13)-d₆ is the deuterium labeled Efaproxiral (HY-13619). Efaproxiral is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .

HY-13619AR

Efaproxiral sodium (Standard) RSR13 sodium (Standard)	Reference Standards	Cancer
Efaproxiral (RSR13) sodium (Standard) is the analytical standard of Efaproxiral sodium (HY-13619A). This product is intended for research and analytical applications. Efaproxiral sodium is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral sodium decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .

HY-13619R

Efaproxiral (Standard) RSR13 (Standard)	Reference Standards	Cancer
Efaproxiral (RSR13) (Standard) is the analytical standard of Efaproxiral (HY-13619). This product is intended for research and analytical applications. Efaproxiral is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .

HY-173107S

Haemoglobin HbA0 (a2b2), U-15N	Isotope-Labeled Compounds	Others
Haemoglobin HbA0 (a2b2), U- ¹⁵N is the ¹⁵N-labeled Haemoglobin Haemoglobin HbA0 (a2b2), U.

HY-173108S

Haemoglobin HbA2 (a2d2), U-15N	Isotope-Labeled Compounds	Others
Haemoglobin HbA2 (a2d2), U- ¹⁵N is the ¹⁵N-labeled Haemoglobin HbA2 (a2d2), U.

HY-106991

Amustaline S-303	CHIKV Dengue Virus Flavivirus	Infection
Amustaline (S-303) is a compound used for inactivating pathogens in blood components and belongs to the category of nucleic acid-targeted chemical decontaminants. Amustaline has the ability to inactivate viruses and is effective against mosquito-borne viruses such as Chikungunya virus (CHIKV), Dengue virus (DENV), and Zika virus (ZIKV). When combined with glutathione (Glutathione, GSH), which acts as a neutralizer to counteract adverse reactions, Amustaline ensures the stability of red blood cell membranes. Amustaline is mainly used for inactivating pathogens in red blood cell concentrates (RBCC) to reduce the risk of transfusion-transmitted infections (TTI) .

HY-135514R

Lys-Phe (Standard) H-Lys-Phe-OH (Standard)	Others Reference Standards	Cardiovascular Disease
Lys-Phe (Standard) is the analytical standard of Lys-Phe. This product is intended for research and analytical applications. Lys-Phe is a dipeptide that inhibits both cell sickling and the gelation of solutions of sickle-cell haemoglobin .

HY-182683

MMV085203	Parasite TrxR Reactive Oxygen Species (ROS)	Infection
MMV085203 is a potent Plasmodium falciparum inhibitor, with a PfTrxR EC₅₀ of 900 nM. MMV085203 exerts potent antimalarial activity against both blood‑stage and sexual‑stage Plasmodium falciparum parasites, with superior efficacy toward clinical isolates of high clonal diversity. MMV085203 modulates parasite redox homeostasis, induces ROS production, and elevates mitochondrial TCA cycle intermediates. MMV085203 can be used for the research of malaria .

Hemoglobin porcine	Biochemical Assay Reagents
Hemoglobin porcine is an oxygen-transporting protein present in the blood of domestic pigs, and also an oxygen carrier with higher oxygen affinity than human hemoglobin. Hemoglobin porcine exhibits cooperative oxygen-binding properties, with weaker heme-heme interactions than those of human hemoglobin .

Cat. No.	Product Name	Target	Research Area

HY-135514

Lys-Phe H-Lys-Phe-OH	Amino Acid Derivatives	Cardiovascular Disease
Lys-Phe is a dipeptide that inhibits both cell sickling and the gelation of solutions of sickle-cell haemoglobin .

HY-135514R

Lys-Phe (Standard) H-Lys-Phe-OH (Standard)	Peptides Reference Standards	Cardiovascular Disease
Lys-Phe (Standard) is the analytical standard of Lys-Phe. This product is intended for research and analytical applications. Lys-Phe is a dipeptide that inhibits both cell sickling and the gelation of solutions of sickle-cell haemoglobin .

Cat. No.	Product Name	Target	Research Area	Image

HY-114134

Epoetin beta rhEPO; EPOCH; Genetical recombination	Inhibitory Antibodies	Metabolic Disease Cancer
Epoetin beta (rhEPO) is a recombinant form of erythropoietin. Epoetin beta is responsible for the maintenance of erythropoiesis and can be used for anaemia research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-101193R

Zinc Protoporphyrin (Standard) Zn(II)-protoporphyrin IX (Standard); ZnPP (Standard); Zinc Protoporphyrin-9 (Standard)	Structural Classification Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis
Zinc Protoporphyrin (Standard) is the analytical standard of Zinc Protoporphyrin. This product is intended for research and analytical applications. Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2 . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .

Cat. No.	Product Name	Chemical Structure

HY-W728761

Voxelotor-d7
Voxelotor-d7 is the deuterium labeled Voxelotor (HY-18681). Voxelotor is a potent inhibitor of haemoglobin S (HbS) polymerization .

HY-18681S

Voxelotor-d6
Voxelotor-d₆ (GBT 440-d₆) is deuterium labeled Voxelotor. Voxelotor (GBT 440) is a potent inhibitor of haemoglobin S (HbS) polymerization. Voxelotor has the potential for sickle cell disease (SCD) treatment .

HY-13619S

Efaproxiral-d6
Efaproxiral (RSR13)-d₆ is the deuterium labeled Efaproxiral (HY-13619). Efaproxiral is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .

HY-173107S

Haemoglobin HbA0 (a2b2), U-15N
Haemoglobin HbA0 (a2b2), U- ¹⁵N is the ¹⁵N-labeled Haemoglobin Haemoglobin HbA0 (a2b2), U.

HY-173108S

Haemoglobin HbA2 (a2d2), U-15N
Haemoglobin HbA2 (a2d2), U- ¹⁵N is the ¹⁵N-labeled Haemoglobin HbA2 (a2d2), U.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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