19 Results for "

human α-amylase

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "human α-amylase" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N0668
CAS No.: 64849-39-4
Rubusoside is a diterpene glycoside that is also a sweetener and solubilizer with anti-angiogenic, anti-cancer, anti-obesity, anti-allergic and anti-asthmatic effects. Rubusoside attenuates airway hyperresponsiveness and reduces inflammatory cells in bronchoalveolar lavage fluid (BALF), reducing OVA (HY-W250978)-induced airway inflammation. Rubusoside also prevents palmitic acid-induced lipotoxicity in pancreatic INS-1 cells, reduces the transport of human glucose transporters GLUT-1 and fructose GLUT-5, and inhibits NF-κB and α-amylase (α-amylase) .
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1
1 Cited Publications
Cat. No.: HY-N1495
CAS No.: 34620-76-3
Synonyms: Maltopentose
Maltopentaose is the shortest chain oligosaccharide. Maltopentaose is a substrate for α-amylases. Maltopentaose can be classified as maltodextrin and is also used in a study to investigate glycation and phosphorylation of α-lactalbumin. Maltopentaose is used to study the inhibition kinetics of human pancreatic α-amylase by dehydrodieugenol B .
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Cat. No.: HY-B2193A
CAS No.: 9000-90-2
Synonyms: 1,4-alpha-D-Glucan-glucanohydrolase, ptyalin
α-Amylase, Human Saliva (1,4-alpha-D-Glucan-glucanohydrolase) is a hydrolase enzyme that can be isolated from human saliva. α-Amylase, Human Saliva catalyses the hydrolysis of internal α-1, 4-glycosidic linkages in starch to yield products like glucose and maltose. α-Amylase, Human Saliva can be used in life science research .
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Cat. No.: HY-112835
CAS No.: 96597-16-9
Purity:  99.42%
Synonyms: pNP-G7
Target:  

Amylases Glycosidase

Research Areas:  

Inflammation/Immunology

Ethylidene-4-nitrophenyl-α-D-Maltoheptaoside (EPS; pNP-G7) serves as a substrate for α-amylase. In the presence of an auxiliary enzyme such as α-glucosidase (α-glucosidase), Ethylidene-4-nitrophenyl-α-D-Maltoheptaoside is degraded by amylase (Amylase) to release a chromophore, enabling the measurement of amylase activity. Ethylidene-4-nitrophenyl-α-D-Maltoheptaoside is applicable for the diagnosis of pancreatitis [2].
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Cat. No.: HY-B2193B
CAS No.: 9000-90-2
Synonyms: amylase, a-amylase, 1,4-a-D-glucan glucanohydrolase, glycogenase
Research Areas:  

Others

α-Amylase, Human Pancreas (Amylase) is a hydrolase enzyme that can be isolated from human pancreas. α-Amylase, Human Pancreas catalyses the hydrolysis of internal α-1, 4-glycosidic linkages in starch to yield products like glucose and maltose. α-Amylase, Human Pancreas can be used in life science research .
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Cat. No.: HY-135530
CAS No.: 5424-20-4
Purity:  ≥96.0%
Chinese gallotannin is a non-specific promiscuous α-amylase inhibitor with a Ki of 0.82 μg/mL for human salivary α-amylase. Chinese gallotannin can be used for the research of diabetes .
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Cat. No.: HY-N9454
CAS No.: 91893-83-3
Garcinoic acid is an orally active anti-inflammatory agent that crosses the blood-brain barrier. Garcinoic acid also enhances efferocytosis and enzyme/receptor regulation, and selectively inhibits human COX-2, porcine α-amylase, Saccharomyces cerevisiae α-glucosidase and human DNA polymerase β (IC50=11 μM), as well as activates human PXR. Garcinoic acid enhances macrophage efferocytosis via receptors such as MerTK and LRP-1, and promotes the production of pro-resolving lipid mediators. Garcinoic acid inhibits NF-κB activation and pro-inflammatory cytokine secretion, interferes with aggregation, downregulates NLRP3 inflammasome activity, and binds to targets including CD44 and EGFR to inhibit leukemia cell proliferation. The pharmacological activities of Garcinoic acid, such as antioxidant, anti-inflammatory and lipid metabolism-regulating effects, are widely used in studies related to various diseases including atherosclerosis, Alzheimer's disease, type 2 diabetes, inflammatory bowel disease and viral pneumonia .
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Cat. No.: HY-W008168
CAS No.: 5470-96-2
Synonyms: 2-Quinolinecarboxaldehyde
Quinoline-2-carboxaldehyde (2-Quinolinecarboxaldehyde) is a quinoline derivative that serves as a synthetic precursor for Schiff base copper complexes. Quinoline-2-carboxaldehyde is applicable to research related to the synthetic design of biomaterials or organic compounds, such as fluorescent sensors .
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Cat. No.: HY-N0668R
CAS No.: 64849-39-4
Rubusoside (Standard) is the analytical standard of Rubusoside. This product is intended for research and analytical applications. Rubusoside is a diterpene glycoside that is also a sweetener and solubilizer with anti-angiogenic, anti-cancer, anti-obesity, anti-allergic and anti-asthmatic effects. Rubusoside attenuates airway hyperresponsiveness and reduces inflammatory cells in bronchoalveolar lavage fluid (BALF), reducing OVA (HY-W250978)-induced airway inflammation. Rubusoside also prevents palmitic acid-induced lipotoxicity in pancreatic INS-1 cells, reduces the transport of human glucose transporters GLUT-1 and fructose GLUT-5, and inhibits NF-κB and α-amylase (α-amylase) .
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Cat. No.: HY-W207699
CAS No.: 27052-20-6
MAO-B-IN-46 (Compound 16) is a selective hMAO-B inhibitor (IC50: 26.8 nM), with weak activity against hMAO-A (IC50: 7.2054 μM). MAO-B-IN-46 (Compound 8) also acts as an α-amylase inhibitor (IC50: 19.46 μM). MAO-B-IN-46 exhibits certain neuroprotective effects and shows no significant toxicity to human gingival fibroblasts and SH-SY5Y cells. Additionally, MAO-B-IN-46 can scavenge DPPH and ABTS free radicals, with IC50 values of 17.86 μM and 17.71 μM, respectively. MAO-B-IN-46 can be used in the research of neurodegenerative diseases such as Parkinson's disease, diabetes, and diseases related to oxidative stress resistance .
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Cat. No.: HY-143268
Target:  

Amylases Glycosidase

Research Areas:  

Metabolic Disease

HPA-IN-1 (Compound 1) is a potent and selective human pancreatic α-amylase (HPA) inhibitor with IC50 values of 12.0 μM and 410.4 μM against HPA and α-glucosidase, respectively .
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Cat. No.: HY-143269
CAS No.: 2885971-91-3
Target:  

Amylases Glycosidase

Research Areas:  

Metabolic Disease

HPA-IN-2 (Compound 2a-1) is a potent and selective human pancreatic α-amylase (HPA) inhibitor with IC50 values of 8.2 μM and 450.7 μM against HPA and α-glucosidase, respectively .
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Cat. No.: HY-168074
4″-C18 EGCG is a potent inhibitor of α-amylase and α-glucosidase with IC50 values of 3.74 and 0.81 μM, respectively. 4″-C18 EGCG inhibits carbohydrate hydrolases, reduces oxidative stress and inflammation, and exhibits antidiabetic activity. 4″-C18 EGCG also downregulates proinflammatory cytokines and is cytotoxic to primary human peripheral blood mononuclear cells (PBMCs), non-cancer cell lines 3T3-L1, and HEK 293 at 50 μM .
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Cat. No.: HY-P7500
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AMY2B; Alpha-amylase 2B; Prev. AMY2; Glycogenase; 1,4-Alpha-D-Glucan Glucanohydrolase 2B; AMY3; amylase Alpha 2B (Pancreatic); HXA; Carcinoid Alpha-amylase; amylase Alpha 2B; amylase, Alpha 2B; Pancreatic
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76722
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AMY2A; PA; Prev. AMY2; Pancreatic amylase Alpha 2A; 1,4-Alpha-D-Glucan Glucanohydrolase; Alpha-amylase; amylase Alpha 2A (Pancreatic); Glycogenase; Pancreatic Alpha-amylase; amylase Alpha 2A; amylase, Alpha 2A; Pancreatic
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-184382
Target:  

Glycosidase

Research Areas:  

Inflammation/Immunology

α-Amylase-IN-15 is a dual inhibitor of α-amylase and α-glucosidase, with IC50 values of 6.7 μM and 18.55 μM, respectively, and a Ki value of 50.9 μM against α-amylase. α-Amylase-IN-15 binds to both free α-amylase and the enzyme-substrate complex. By inhibiting α-glucosidase, α-Amylase-IN-15 achieves dual inhibition of carbohydrate metabolic enzymes. α-Amylase-IN-15 can be used in the research of type 2 diabetes .
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Cat. No.: HY-184383
Target:  

Glycosidase Amylases

Research Areas:  

Metabolic Disease

α-Amylase/α-Glucosidase-IN-25 is a α-Amylase inhibitor and a competitive α-Glucosidase inhibitor, with an IC50 of 10.89 μM against α-glucosidase and an IC50 of 20.62 μM against α-amylase. α-Amylase/α-Glucosidase-IN-25 limits carbohydrate digestion. α-Amylase/α-Glucosidase-IN-25 can be used in the research of type 2 diabetes .
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Cat. No.: HY-N17294
CAS No.: 603995-11-5
Dendromoniliside D is a sesquiterpene glycoside. Dendromoniliside D can be isolated from D. nobile. Dendromoniliside D inhibits α-amylase. Dendromoniliside D can be used in the research of liver cancer, lung cancer, and breast cancer .
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Cat. No.: HY-N11852
CAS No.: 51415-08-8
Momilactone B is an inhibitor of α-amylase and α-glucosidase, with an IC50 of 146.85 μg/mL against Aspergillus oryzae α-amylase and an IC50 of 612.03 μg/mL against Saccharomyces cerevisiae α-glucosidase. Momilactone B upregulates the expression of p21 Waf1/Cip1, reduces the kinase activity of Cdk4 and Cdk6, induces cell cycle arrest and apoptosis in cancer cells, and triggers irreversible cell death via cell membrane damage. Momilactone B inhibits the growth of neighboring plant species and serves as a major contributing factor to the allelopathy of rice. Momilactone B can be used in studies related to rice allelopathy, type 2 diabetes, colon cancer and leukemia .
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