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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
126 Results for "
human epidermal growth factor receptor
" in MedChemExpress (MCE) Product Catalog:
Products (126)
126 Results for "human epidermal growth factor receptor" in MCE Product Catalog:
57
Research Areas:
Cetuximab (C225) is a human IgG1 monoclonal antibody that inhibits epidermal growth factor receptor (EGFR), with a Kd of 0.201 nM for EGFR by SPR. Cetuximab has potent antitumor activity .
12
12 Cited Publications
Synonyms: T-DXd (solution); DS-8201 (solution); DS-8201a (solution)
Target:
Research Areas:
Trastuzumab deruxtecan (T-DXd; DS-8201a) (solution) is an anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate (ADC). Trastuzumab deruxtecan is composed of a humanized anti-HER2 antibody, an enzymatically cleavable peptide-linker, a topoisomerase I inhibitor (a toxin component of Dxd), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). Trastuzumab deruxtecan can be used for the research of HER2-positive breast cancer and gastric cancer .
12
12 Cited Publications
Synonyms: T-DXd; DS-8201; DS-8201a
Target:
Research Areas:
Trastuzumab deruxtecan (DS-8201a) is an anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate (ADC). Trastuzumab deruxtecan is composed of a humanized anti-HER2 antibody, an enzymatically cleavable peptide-linker, a topoisomerase I inhibitor (a toxin component of Dxd), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). Trastuzumab deruxtecan can be used for the research of HER2-positive breast cancer and gastric cancer .
5
5 Cited Publications
Cat. No.: HY-P0221
CAS No.: 137061-48-4
Synonyms: Pituitary Adenylate Cyclase Activating Polypeptide 38
Research Areas:
3
3 Cited Publications
Cat. No.: HY-P7017
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HBEGF; Diphtheria Toxin receptor (Heparin-Binding EGF-Like growth factor); Prev. HEGFL; Heparin-Binding epidermal growth factor; Prev. DTR; Short Form Heparin-Binding EGF-Like growth factor; Prev. DTS; Heparin-Binding EGF-Like growth factor; Diphtheria To
Species:
Human
Source:
E. coli
3
3 Cited Publications
Cat. No.: HY-P7400
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HBEGF; Diphtheria Toxin receptor (Heparin-Binding EGF-Like growth factor); Prev. HEGFL; Heparin-Binding epidermal growth factor; Prev. DTR; Short Form Heparin-Binding EGF-Like growth factor; Prev. DTS; Heparin-Binding EGF-Like growth factor; Diphtheria To
Species:
Human
Source:
CHO
2
Target:
Research Areas:
2
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-P72987
Purity: ≥ 75%, as determined by reducing SDS-PAGE.
Synonyms: EGFR; epidermal growth factor receptor Variant EX12_14del; Prev. ERBB; Cell Proliferation-Inducing Protein 61; ERBB1; Cell growth Inhibiting Protein 40; ERRP; receptor Protein-Tyrosine Kinase; receptor Tyrosine-Protein Kinase ErbB-1; Alternative Protein E
Species:
Human
Source:
Sf9 insect cells
2
2 Cited Publications
Cat. No.: HY-P73094
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ERBB2; P185erbB2; Prev. NGL; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (Neuro/Glioblastoma Derived Oncogene Homolog); HER2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2 Isoform C; receptor Tyrosine-Protein Kinase ErbB-2; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2; Proto-Oncogene C-ErbB-2; Neuroblastoma/Glioblastoma Derived Oncogene Homolog; Proto-Oncogene Neu; receptor Tyrosine-Protein Kinase ErbB-2 Variant; P185(ErbB2); Truncated HER2 Splice Variant P100; C-ERB-2; receptor Protein-Tyrosine Kinase; C-ERB2; Metastatic Lymph Node Gene 19; MLN-19; Alternative Protein ERBB2; HER-2; C-Erb B2/Neu Protein; CD340; CD340 Antigen; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; HER-2/Neu; Tyrosine Kinase-Type Cell Surface receptor HER2; Herstatin; Neuro/Glioblastoma Derived Oncogene Homolog; VSCN2; human epidermal growth factor receptor 2; MLN19; Metastatic Lymph Node Gene 19 Protein; TKR1; Erb-B2 receptor Tyrosine Kinase 2; MLN 19
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P74177
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EGFR; epidermal growth factor receptor Variant EX12_14del; Prev. ERBB; Cell Proliferation-Inducing Protein 61; ERBB1; Cell growth Inhibiting Protein 40; ERRP; receptor Protein-Tyrosine Kinase; receptor Tyrosine-Protein Kinase ErbB-1; Alternative Protein EGFR; Erb-B2 receptor Tyrosine Kinase 1; epidermal growth factor; Proto-Oncogene C-ErbB-1; EGFR VIII; HER1; NISBD2; epidermal growth factor receptor (Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog); NNCIS; Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog (Avian); PIG61; Avian Erythroblastic Leukemia Viral (V-Erb-B) Oncogene Homolog; MENA; epidermal growth factor receptor Tyrosine Kinase Domain; epidermal growth factor receptor; epidermal growth factor receptor Variant EX12_15del
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P72487
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HBEGF; Diphtheria Toxin receptor (Heparin-Binding EGF-Like growth factor); Prev. HEGFL; Heparin-Binding epidermal growth factor; Prev. DTR; Short Form Heparin-Binding EGF-Like growth factor; Prev. DTS; Heparin-Binding EGF-Like growth factor; Diphtheria To
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P70608
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: EGFR; epidermal growth factor receptor Variant EX12_14del; Prev. ERBB; Cell Proliferation-Inducing Protein 61; ERBB1; Cell growth Inhibiting Protein 40; ERRP; receptor Protein-Tyrosine Kinase; receptor Tyrosine-Protein Kinase ErbB-1; Alternative Protein E
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P70322
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ERBB3; receptor Protein-Tyrosine Kinase; Prev. LCCS2; P45-SErbB3; HER3; P85-SErbB3; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3; ErbB-3 R31; Tyrosine Kinase-Type Cell Surface receptor HER3; MDA-BF-1; human epidermal growth factor Recep
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P80116
Synonyms: Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody;
Cell growth inhibiting protein 40 antibody;
Cell proliferation inducing protein 61 antibody;
EGF R antibody;
EGFR antibody;
EGFR_human antibody;
epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) antibody;
epidermal growth factor receptor antibody;
erb-b2 receptor tyrosine kinase 1 antibody;
ERBB antibody;
ERBB1 antibody;
Errp antibody;
HER1 antibody;
mENA antibody;
NISBD2 antibody;
Oncogen ERBB antibody;
PIG61 antibody;
Proto-oncogene c-ErbB-1 antibody;
receptor tyrosine protein kinase ErbB 1 antibody;
receptor tyrosine-protein kinase ErbB-1 antibody;
SA7 antibody;
Species antigen 7 antibody;
Urogastrone antibody;
v-erb-b Avian erythroblastic leukemia viral oncogen homolog antibody;
wa2 antibody;
Wa5 antibody
Cat. No.: HY-164202
Research Areas:
ORM-5029 is a first-in-class human epidermal growth factor receptor 2 (HER2)-targeted antibody-drug conjugate (ADC) comprised of SMol006, a highly potent GSPT1 degrader, conjugated to Pertuzumab (HY-P9912). ORM-5029 exhibits robust efficacy across 14 HER2-positive breast cancer cell lines, with IC50 values ranging from 0.3 to 14.4 nM.ORM-5029 demonstrates anti-tumor activity in the BT474 xenograft model. ORM-5029 can be used for study of breast cancer .
Cat. No.: HY-P99268
CAS No.: 1334296-12-6
Synonyms: SAR 256212; MM 121
Cat. No.: HY-P99618
CAS No.: 2377419-89-9
Synonyms: IBI-315; BH2950
Target:
Research Areas:
Cat. No.: HY-P99941
CAS No.: 2079108-44-2
Synonyms: INCMGA-00012; MGA-012
Target:
Research Areas:
Cat. No.: HY-P10697A
Target:
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
