6 Results for "

hyperkalemia

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "hyperkalemia" in MCE Product Catalog:

Cat. No.: HY-107929
CAS No.: 37286-92-3
Synonyms: Poly(styrenesulfonic acid) calcium salt
Target:  

Potassium Channel

Research Areas:  

Metabolic Disease

Calcium polystyrene sulfonate (Poly(styrenesulfonic acid) calcium salt) is an orally active potassium-lowering agent. Calcium polystyrene sulfonate binds potassium in the distal colon in exchange for Ca 2+. Calcium polystyrene sulfonate can be used for the research of hyperkalemia in chronic kidney disease .
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Cat. No.: HY-112961
CAS No.: 1208912-84-8
Purity:  ≥95.0%
Research Areas:  

Metabolic Disease

Patiromer is an orally active, selective and non-absorbable intestinal potassium (K +) polymer binder that reversibly binds potassium ions in exchange for calcium (Ca 2+). Patiromer can rapidly and continuously reduce serum potassium levels, maintain a normal blood potassium state, and reduce serum aldosterone levels. Patiromer also increases fecal potassium excretion. Patiromer is mainly used in the study of hyperkalemia associated with diseases such as chronic kidney disease, diabetes, and heart failure, and is particularly suitable for improving renin-angiotensin-aldosterone system inhibitor (RAASi) therapy .
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Cat. No.: HY-147406
CAS No.: 2589926-20-3
Synonyms: ION-904
Tonlamarsen (ION-904) is a GalNAc-conjugated antisense oligonucleotide and Angiotensinogen synthesis inhibitor. Tonlamarsen specifically reduces the production of Angiotensinogen in the liver and plasma, and exhibits extremely low activity in the kidneys. Tonlamarsen can be used in research related to hypertension and heart failure .
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Cat. No.: HY-120321
CAS No.: 1355687-91-0
DSR-71167 is an orally active mineralocorticoid receptor (MR) antagonist with an IC50 of 0.26 μM. DSR-71167 exhibits weak carbonic anhydrase (CA) inhibitory activity with an IC50 of 19 μM. DSR-71167 can dose-dependently increase urinary sodium excretion in rat models and has a very low risk of hyperkalemia in potassium-loading rat models. DSR-71167 lowers systolic blood pressure in hypertensive rat models. DSR-71167 can be used for research on hypertension and heart failure .
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Cat. No.: HY-P3565
CAS No.: 1446991-36-1
Synonyms: STX-b
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease

Sarafotoxin S6d (STX-b) is a polypeptide toxin isolated from the venom of the Israeli sand boa constrictor. Sarafotoxin S6d induces multiple electrocardiogram (ECG) changes including myocardial ischemia and hyperkalemia. Sarafotoxin S6d induces strong extracellular calcium-dependent vasoconstriction in rat aorta and exhibits positive inotropic effects in rat atria. Sarafotoxin S6d can be used in the study of cardiovascular diseases .
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Cat. No.: HY-147406A
CAS No.: 2589926-21-4
Synonyms: ION-904 sodium
Tonlamarsen (ION-904) sodium is a GalNAc-conjugated antisense oligonucleotide and Angiotensinogen synthesis inhibitor. Tonlamarsen sodium specifically reduces the production of Angiotensinogen in the liver and plasma, and exhibits extremely low activity in the kidneys. Tonlamarsen sodium can be used in research related to hypertension and heart failure .
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