5 Results for "

icaritin

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "icaritin" in MCE Product Catalog:

11
11 Cited Publications
Cat. No.: HY-N0678
CAS No.: 118525-40-9
Synonyms: Anhydroicaritin
Icaritin (Anhydroicaritin) is a prenylflavonoid derivative from Epimedium brevicornuMaxim. and potently inhibits proliferation of K562 cells (IC50 of 8 µM) and primary CML cells (IC50 of 13.4 µM for CML-CP and 18 µM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings, also enhances osteogenesis [3.
loading...
    loading...
Cat. No.: HY-N0678R
CAS No.: 118525-40-9
Synonyms: Anhydroicaritin (Standard)
Icaritin (Standard) is the analytical standard of Icaritin. This product is intended for research and analytical applications. Icaritin (Anhydroicaritin) is a prenylflavonoid derivative from Epimedium brevicornuMaxim. and potently inhibits proliferation of K562 cells (IC50 of 8 μM) and primary CML cells (IC50 of 13.4 μM for CML-CP and 18 μM for CML-BC). Icaritin can regulate MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings, also enhances osteogenesis [3.
loading...
    loading...
Cat. No.: HY-N13128
CAS No.: 108195-76-2
Icaritin-3-O-rhamnoside (compound 20) is a flavonoid compound that exhibits DPPH radical scavenging activity (IC50=227.9 μM) .
loading...
    loading...
Cat. No.: HY-149063
CAS No.: 2922842-01-9
Target:  

Apoptosis

Research Areas:  

Cancer

Antitumor agent-92, an Icaritin (HY-N0678) derivative, causes arrest at the G0/G1 phase in the cell cycle and induces cell apoptosis. Antitumor agent-92 has the potential for hepatocellular carcinoma (HCC) research .
loading...
    loading...
Cat. No.: HY-N19800
CAS No.: 1231899-06-1
Anhydroicaritin-3,7-di-O-glucuronide is a diglucuronide metabolite of icaritin. Anhydroicaritin-3,7-di-O-glucuronide is also a conjugated metabolite derived from prenylated flavonoids of the genus *Epimedium* in rats. In an in vitro microsomal system, Anhydroicaritin-3,7-di-O-glucuronide is mainly catalyzed by UGT1A1 and UGT1A8. Anhydroicaritin-3,7-di-O-glucuronide is generated via sequential glucuronidation at the 3-OH and 7-OH sites of icaritin, or via further conversion from monoglucuronides of icaritin .
loading...
    loading...