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Results for "

iris

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Receptor (1) Apoptosis (1) Biochemical Assay Reagents (1) Drug Derivative (1) Drug Intermediate (1) Drug Metabolite (1) Endogenous Metabolite (1) mAChR (1) Prostaglandin Receptor (3) Reference Standards (2) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (4) Inflammation/Immunology (3) Metabolic Disease (4) Neurological Disease (2)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Natural
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Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N6819

Iristectorin B	Others	Cancer
Iristectorin B is an isoflavone from Iris tectorum, has anti-cancer activities in breast cancer .

HY-N6820

Iristectorin A	Others	Cancer
Iristectorin A, a natural product from Iris tectorum, has anti-cancer activities in breast cancer .

HY-RS01593

BRCA1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
BRCA1 Human Pre-designed siRNA Set A contains three designed siRNAs for BRCA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

BRCA1 Human Pre-designed siRNA Set A BRCA1 Human Pre-designed siRNA Set A

HY-116211

Amfonelic acid WIN-25978	Biochemical Assay Reagents	Neurological Disease
Amfonelic acid (WIN-25978) is a highly selective dopamine reuptake inhibitor. Amfonelic acid interferes with the in vitro neuronal uptake of norepinephrine in the iris of rats, but does not alter the concentrations of norepinephrine or dopamine in the whole mouse brain. Amfonelic acid can be used as a pharmacological tool to study the brain reward system, dopamine pathway and dopamine transporter .

HY-116161A

17-Phenyl trinor PGF2α isopropyl ester	Prostaglandin Receptor	Metabolic Disease
17-Phenyl trinor PGF₂α isopropyl ester is a FP receptor agonist and intraocular pressure-lowering agent. 17-Phenyl trinor PGF₂α isopropyl ester induces iris sphincter contraction, reduces intraocular pressure and pupil diameter, causes no ocular irritation, and only leads to mild conjunctival hyperemia. 17-Phenyl trinor PGF₂α isopropyl ester is applicable to relevant research on glaucoma .

HY-13938

Iretol 1 Publications Verification	Endogenous Metabolite	Metabolic Disease
Iretol (2,4,6-trihydroxyanisole) is a a degradation product of a glucoside obtained from Iris Jorentina. Iretol is an intermediate in the synthesis of natural isoflavones, such as Tectorigenin, Irigenin and Caviunin .

HY-N16552

Embinin	Apoptosis	Cardiovascular Disease
Embinin is a natural product that can be isolated from Petals of Iris germanica Linnaeous. Embinin can enhance lumbar disc neovascularization and induces apoptosis of nucleus pulposus cells in lumbar disc herniation rats .

HY-N11537

2-Methoxy-6-pentadecyl-1,4-benzoquinone	Others	Others
2-Methoxy-6-pentadecyl-1,4-benzoquinone (1c) is a pentadecyl derivative that can be isolated from seed oils of different iris plants such as I. pseudacorus, I. missouriensis and I. sibirica .

HY-116161

Bimatoprost isopropyl ester	Drug Intermediate	Cardiovascular Disease Others
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC₅₀ values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.1 A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.

HY-N7593

Tectoruside	Others	Inflammation/Immunology
Tectoruside is a phenol acid glycoside of the rhizome of Iris dichotoma Pall. Iris dichotoma Pall, a traditional Chinese herbal medicine, has been used in several disorders such as inflammation, throat disorders, asthma and coughs .

HY-N8913

Iristectorene B	Others	Others
Iristectorene B is a Triterpenoids product that can be isolated from the seeds of Iris tectorum. .

HY-N11789

3-Hydroxyirisquinone	Others	Others
3-Hydroxyirisquinone is a quinone derivative, which can isolated from the seeds of Iris bungei Maxim .

HY-N8859

Isoiridogermanal 16-Hydroxyiridal	Others	Others
Isoiridogermanal can be isolated from the extract of rhizomes of Iris tectorum Maxim. Isoiridogermanal is cytotoxic with IC50 values of 11 μM and 23 μM against MCF-7 and C32 cell lines.

HY-N2189R

Swertisin (Standard)	Reference Standards Adenosine Receptor	Metabolic Disease Inflammation/Immunology
Swertisin (Standard) is the analytical standard of Swertisin. This product is intended for research and analytical applications. Swertisin, a C-glucosylflavone isolated from Iris tectorum, is known to have antidiabetic, anti-inflammatory and antioxidant effects. Swertisin is an adenosine A1 receptor antagonist .

HY-126115

15(S)-Latanoprost 15-epi Latanoprost	Prostaglandin Receptor	Cardiovascular Disease Others
15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC₅₀ values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 μg dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys.

HY-126115R

15(S)-Latanoprost (Standard) 15-epi Latanoprost (Standard)	Prostaglandin Receptor Reference Standards	Cardiovascular Disease Others
15(S)-Latanoprost (Standard) is the analytical standard of 15(S)-Latanoprost. This product is intended for research and analytical applications. 15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 μg dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys.

HY-N7857

19(R)-Hydroxy-prostaglandin F2α 19(R)-Hydroxy PGF2α	Drug Metabolite	Metabolic Disease
19(R)-Hydroxy-prostaglandin F2α (19(R)-hydroxy PGF2α) is an ω-1 hydroxylase metabolite of PGF2α found in human semen. The concentration of 19(R)-Hydroxy-PGFs compounds (F2α and F1α together) in fresh human semen is about 20 μg/mL. 19(R)-Hydroxy-prostaglandin F2α exhibits no activity at the FP receptor of the cat iris sphincter muscle at concentrations up to 1 μM.

HY-175097

AL 8810 Ethyl amide	Drug Derivative	Others
AL 8810 Ethyl amide is an acetamide derivative of AL-8810 (HY-100449). AL 8810 Ethyl amide dose not exhibit a significant antagonistic effect on the action of PGF_2α, and it dose not cause the contraction of the cat iris .

HY-N17466

(7S,7′R,8S,8′S)-neo-Olivil	Others	Cancer
(7S,7′R,8S,8′S)-neo-Olivil is a lignan present in the rhizome of Iris tectorum. (7S,7′R,8S,8′S)-neo-Olivil shows no significant cytotoxicity against human tumor cells at a concentration of 10 μM .

HY-183932

NPC-14695	mAChR	Neurological Disease Inflammation/Immunology
NPC-14695 is a competitive and selective M3 muscarinic receptor antagonist, with a K_d value of 15 nM for guinea pig M3, 60 nM for guinea pig M2, and 25 nM for rabbit M1. NPC-14695 exhibits higher activity towards M3 receptors in bronchial smooth muscle than towards those regulating salivary secretion. NPC-14695 inhibits Carbachol (HY-B1208)-induced contraction of isolated rabbit iris smooth muscle .

Iristectorin B	Flavonoids Iridaceae Classification of Application Fields Phenols Polyphenols Plants Belamcanda chinensis (Linn.) Redouté Disease Research Fields Isoflavones Cancer Source Classification	Others
Iristectorin B is an isoflavone from Iris tectorum, has anti-cancer activities in breast cancer .

Iristectorin A	Flavonoids Iridaceae Classification of Application Fields Phenols Polyphenols Plants Belamcanda chinensis (Linn.) Redouté Disease Research Fields Isoflavones Cancer Source Classification	Others
Iristectorin A, a natural product from Iris tectorum, has anti-cancer activities in breast cancer .

Iretol 1 Publications Verification	Classification of Application Fields Phenols Polyphenols Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Iretol (2,4,6-trihydroxyanisole) is a a degradation product of a glucoside obtained from Iris Jorentina. Iretol is an intermediate in the synthesis of natural isoflavones, such as Tectorigenin, Irigenin and Caviunin .

Embinin	Structural Classification Flavonoids Iridaceae Flavones Plants Source Classification	Apoptosis
Embinin is a natural product that can be isolated from Petals of Iris germanica Linnaeous. Embinin can enhance lumbar disc neovascularization and induces apoptosis of nucleus pulposus cells in lumbar disc herniation rats .

Tectoruside	Iris tectorum Maxim. Iridaceae Classification of Application Fields Ketones, Aldehydes, Acids Lridaceae Plants Disease Research Fields Inflammation/Immunology Source Classification	Others
Tectoruside is a phenol acid glycoside of the rhizome of Iris dichotoma Pall. Iris dichotoma Pall, a traditional Chinese herbal medicine, has been used in several disorders such as inflammation, throat disorders, asthma and coughs .

Iristectorene B	Triterpenes Iris tectorum Maxim. Iridaceae Terpenoids Plants Source Classification	Others
Iristectorene B is a Triterpenoids product that can be isolated from the seeds of Iris tectorum. .

3-Hydroxyirisquinone	Quinones Iridaceae Benzene Quinones Plants Iris bungei Maxim. Source Classification	Others
3-Hydroxyirisquinone is a quinone derivative, which can isolated from the seeds of Iris bungei Maxim .

Isoiridogermanal 16-Hydroxyiridal	Natural Products Lridaceae Plants Source Classification	Others
Isoiridogermanal can be isolated from the extract of rhizomes of Iris tectorum Maxim. Isoiridogermanal is cytotoxic with IC50 values of 11 μM and 23 μM against MCF-7 and C32 cell lines.

Swertisin (Standard)	Iris tectorum Maxim. Flavonoids other families Iridaceae Classification of Application Fields Phenols Metabolic Disease Plants Inflammation/Immunology Disease Research Fields Source Classification	Reference Standards Adenosine Receptor
Swertisin (Standard) is the analytical standard of Swertisin. This product is intended for research and analytical applications. Swertisin, a C-glucosylflavone isolated from Iris tectorum, is known to have antidiabetic, anti-inflammatory and antioxidant effects. Swertisin is an adenosine A1 receptor antagonist .

(7S,7′R,8S,8′S)-neo-Olivil	Structural Classification Iris tectorum Maxim. Iridaceae Lignans Phenylpropanoids Plants Source Classification	Others
(7S,7′R,8S,8′S)-neo-Olivil is a lignan present in the rhizome of Iris tectorum. (7S,7′R,8S,8′S)-neo-Olivil shows no significant cytotoxicity against human tumor cells at a concentration of 10 μM .

Host:	Mouse (2)
Reactivity:	Human (2)
Application:	IHC-P (2) ELISA (2)
Isotype:	IgG1 (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal Antibody (1)
Modification:	Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P84289

	BRCA1 Antibody (YA3986) iris; PSCP; BRCAI; BRCC1; PNCA4; RNF53; BROVCA1; PPP1R53	IHC-P, ELISA	Human
	BRCA1 Antibody (YA3986) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to BRCA1.

HY-P84289A

	BRCA1 Antibody (YA3986)(PBS only) iris; PSCP; BRCAI; BRCC1; PNCA4; RNF53; BROVCA1; PPP1R53	IHC-P, ELISA	Human
	BRCA1 Antibody (YA3986) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to BRCA1.

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BRCA1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
BRCA1 Human Pre-designed siRNA Set A contains three designed siRNAs for BRCA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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