Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
iris
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "iris" in MCE Product Catalog:
1
Target:
Art. -Nr.: HY-N6819
CAS. Nr.: 94396-09-5
Category:
Iridaceae Flavonoids Phenols Polyphenols Plants Belamcanda chinensis (Linn.) Redouté Disease Research Fields Cancer Isoflavones
Target:
Art. -Nr.: HY-N6820
CAS. Nr.: 37744-61-9
Category:
Iridaceae Flavonoids Phenols Polyphenols Plants Belamcanda chinensis (Linn.) Redouté Disease Research Fields Cancer Isoflavones
Target:
Art. -Nr.: HY-RS01593
Target:
Forschungsgebiete:
BRCA1 Human Pre-designed siRNA Set A contains three designed siRNAs for BRCA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-116211
CAS. Nr.: 15180-02-6
Synonyms: WIN-25978
Target:
Forschungsgebiete:
Amfonelic acid (WIN-25978) is a highly selective dopamine reuptake inhibitor. Amfonelic acid interferes with the in vitro neuronal uptake of norepinephrine in the iris of rats, but does not alter the concentrations of norepinephrine or dopamine in the whole mouse brain. Amfonelic acid can be used as a pharmacological tool to study the brain reward system, dopamine pathway and dopamine transporter .
Target:
Forschungsgebiete:
17-Phenyl trinor PGF2α isopropyl ester is a FP receptor agonist and intraocular pressure-lowering agent. 17-Phenyl trinor PGF2α isopropyl ester induces iris sphincter contraction, reduces intraocular pressure and pupil diameter, causes no ocular irritation, and only leads to mild conjunctival hyperemia. 17-Phenyl trinor PGF2α isopropyl ester is applicable to relevant research on glaucoma .
Art. -Nr.: HY-N16552
CAS. Nr.: 52589-13-6
Category:
Target:
Art. -Nr.: HY-N11537
CAS. Nr.: 144078-11-5
2-Methoxy-6-pentadecyl-1,4-benzoquinone (1c) is a pentadecyl derivative that can be isolated from seed oils of different iris plants such as I. pseudacorus, I. missouriensis and I. sibirica .
Art. -Nr.: HY-116161
CAS. Nr.: 130273-87-9
Target:
Forschungsgebiete:
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.1 A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.
Art. -Nr.: HY-N7593
CAS. Nr.: 38784-73-5
Category:
Iris tectorum Maxim. Iridaceae Ketones, Aldehydes, Acids Lridaceae Plants Disease Research Fields Inflammation/Immunology
Target:
Art. -Nr.: HY-N8913
CAS. Nr.: 156791-81-0
Category:
Iris tectorum Maxim. Triterpenes Iridaceae Terpenoids Plants
Target:
Art. -Nr.: HY-N11789
CAS. Nr.: 100205-29-6
Target:
Art. -Nr.: HY-N8859
CAS. Nr.: 86293-25-6
Synonyms: 16-Hydroxyiridal
Category:
Target:
Art. -Nr.: HY-126115
CAS. Nr.: 145773-22-4
Synonyms: 15-epi Latanoprost
Target:
Forschungsgebiete:
15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 μg dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys.
Art. -Nr.: HY-126115R
CAS. Nr.: 145773-22-4
Synonyms: 15-epi Latanoprost (Standard)
Forschungsgebiete:
15(S)-Latanoprost (Standard) is the analytical standard of 15(S)-Latanoprost. This product is intended for research and analytical applications. 15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 μg dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys.
Art. -Nr.: HY-N7857
CAS. Nr.: 64625-53-2
Synonyms: 19(R)-Hydroxy PGF2α
Target:
Forschungsgebiete:
19(R)-Hydroxy-prostaglandin F2α (19(R)-hydroxy PGF2α) is an ω-1 hydroxylase metabolite of PGF2α found in human semen. The concentration of 19(R)-Hydroxy-PGFs compounds (F2α and F1α together) in fresh human semen is about 20 μg/mL. 19(R)-Hydroxy-prostaglandin F2α exhibits no activity at the FP receptor of the cat iris sphincter muscle at concentrations up to 1 μM.
Art. -Nr.: HY-175097
Target:
Forschungsgebiete:
AL 8810 Ethyl amide is an acetamide derivative of AL-8810 (HY-100449). AL 8810 Ethyl amide dose not exhibit a significant antagonistic effect on the action of PGF2α, and it dose not cause the contraction of the cat iris .
Art. -Nr.: HY-P84289A
Synonyms: iris; PSCP; BRCAI; BRCC1; PNCA4; RNF53; BROVCA1; PPP1R53
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
