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Results for "

lipid A

" in MedChemExpress (MCE) Product Catalog:

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2759

Inhibitors & Agonists

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116

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500

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103

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MCE Kits

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587

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Products

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192

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Antibodies

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559

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GMP Molecules

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-138171

Lipid 5 3 Publications Verification	Liposome	Others
Lipid 5 is an amino lipid that affords efficient mRNA delivery in rodent and primate models. Lipid 5 shows optimal pharmacokinetics and non-toxic side effects .

HY-170333

Lipid A-11 CICL1	Liposome	Inflammation/Immunology
Lipid A-11 (Compound A-11) (CICL1) is an ionizable cationic lipid. Lipid A-11 can be used to prepare lipid nanoparticles. Lipid A-11 can be used in research involving T cell-targeted transfection .

HY-130320

*Monophosphoryl lipid* A** Glucopyranosyl lipid A	Toll-like Receptor (TLR)	Inflammation/Immunology Cancer
Monophosphoryl lipid A (Glucopyranosyl lipid A) is a toll-like receptor 4 agonist. Monophosphoryl lipid A is derived from the cell wall of nonpathogenic Salmonella. Monophosphoryl lipid A can be used for the research of immunization and vaccine .

HY-103251

PF-5081090 LpxC-4	Antibiotic Bacterial	Infection
PF-5081090 (LpxC-4) is a potent LpxC inhibitor, is a rapidly bactericidal with broad-spectrum activity. PF-5081090 serves as a regulator of lipid A biosynthesis in Gram-negative pathogens .

HY-153378

Lipid 15	Liposome	Others
Lipid 15 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

HY-149156

Lipid C24	Liposome	Cancer
Lipid C24 is a cationic ionizable lipid that can be used for synthesizing lipid nanoparticles. Lipid C24 can be used in the study of drug delivery .

HY-N8277

*Kdo2-Lipid* A ammonium** 3 Publications Verification	Toll-like Receptor (TLR) TNF Receptor	Cancer
Kdo2-Lipid A ammonium is a chemically defined lipopolysaccharide (LPS) with endotoxin activity equal to LPS. Kdo2-Lipid A ammonium is highly selective for TLR4. Kdo2-Lipid A ammonium stimulates the release of both TNF and PGE2 .

HY-135042

CAY10614 1 Publications Verification	Toll-like Receptor (TLR)	Neurological Disease
CAY10614 is a potent TLR4 antagonist. CAY10614 inhibits the lipid A-induced activation of TLR4, with an IC₅₀ of 1.675 μM. CAY10614 can improve survival of mice in lethal endotoxin shock model .

HY-148648

Lipid 29	Liposome	Others
Lipid 29 is an ionizable amino lipid. Lipid 29 can be used to form lipid nanoparticles .

HY-N16040

DMG-pSar25	Liposome	Others
DMG-pSar25 is a double lipid-tailed polysarcosine lipid with 25 sarcosine moieties, serving as a PEG lipid substitute in lipid nanoparticle formulations for mRNA delivery. DMG-pSar25 supports mRNA delivery in lipid nanoparticle formulations .

HY-156630

*Ionizable lipid-1* 1 Publications Verification	Liposome	Others
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .

HY-112757

DLinDMA 3 Publications Verification	Liposome	Others
DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery .

HY-W782032

*3D-Monophosphoryl Lipid* A-5** 3D-MPLA-5	Toll-like Receptor (TLR)	Inflammation/Immunology
3D-Monophosphoryl Lipid A-5 (3D-MPLA-5) is a TLR agonist that serves as a vaccine adjuvant and enhances the immunogenicity of vaccines .

HY-150115

Lipid 10 1 Publications Verification	Liposome	Others
Lipid 10 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

HY-154974

*LNP Lipid-8*	Liposome	Cancer
LNP Lipid-8 (11-A-M) is an ionizable single-tail multi-head lipid that can be used as a lipid nanoparticle (LNP) to deliver siRNA to T cells without targeting ligands. LNP Lipid-8 is more selective for T cells than other cell types such as hepatocytes. LNP Lipid-8 selectively delivers siRNA/sgRNA to T cells (especially CD8+ T cells) through endogenous lipid transport pathways, and can enter cells and release RNA through endocytosis to achieve gene silencing. LNP Lipid-8 loaded with GFP siRNA (siGFP) significantly led to GFP gene silencing in mouse models. LNP Lipid-8 showed good efficacy and safety in both cells and animals, without obvious liver targeting and toxicity. LNP Lipid-8 can be used for RNA delivery research in the fields of tumor immunotherapy and T cell-mediated autoimmune diseases .

HY-153852

*LNP Lipid-7*	Liposome	Others
LNP Lipid-7 is a cationic lipid. LNP Lipid-7 can be used to prepare lipid nanoparticles (LNPs) for the delivery of drugs such as nucleic acids .

HY-153186

*LNP Lipid-3*	Liposome	Others
LNP Lipid-3 is an ionizable lipid that can be used to synthesize lipid nanoparticles. LNP Lipid-3 can be applied in the research of drug delivery .

HY-160439

*Ionizable lipid-2*	Liposome	Others
Ionizable lipid-2 (Compound 1) is an ionizable lipid that can be used for the preparation of lipid nanoparticles and vaccine research .

HY-159717

Lipid 331	Liposome	Others
Lipid 331 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid 331 is a carrier for both siRNA and mRNA .

HY-153377

Lipid 14	Liposome SARS-CoV Bacterial	Infection Inflammation/Immunology
Lipid 14 is an ionizable amino lipid. Lipid 14 delivers mRNA into target cells, significantly enhancing the in vivo expression efficiency and immunogenicity of mRNA. Lipid 14 can be used to synthesize lipid nanoparticles (LNPs). Lipid 14 can be used for studies of SARS-CoV-2 and Yersinia pestis .

HY-134782

OF-Deg-Lin	Liposome	Others
OF-Deg-Lin is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

HY-D1594

BODIPY TR Cadaverine 3 Publications Verification	Fluorescent Dye	Others
BODIPY TR Cadaverine, a cadaverine derivative, is a red fluorescent dye. BODIPY TR Cadaverine can be used in a a highly sensitive and robust fluorescent displacement assay, which binds to native LPS strongly, specifically recognizing lipid A, and is competitively displaced by compounds displaying an affinity for lipid A .

HY-DY1076

BODIPY TR Cadaverine (solution)	Fluorescent Dye	Others
BODIPY TR Cadaverine (solution) , a cadaverine derivative, is a red fluorescent dye. BODIPY TR Cadaverine can be used in a a highly sensitive and robust fluorescent displacement assay, which binds to native LPS strongly, specifically recognizing lipid A, and is competitively displaced by compounds displaying an affinity for lipid A . Solvent and concentration: DMSO: 2 mM

HY-E70523

Pentanoyl coenzyme A Valeryl-CoA; Valeryl-coenzyme A; Pentanoyl coenzyme A free acid	Endogenous Metabolite	Metabolic Disease
Pentanoyl coenzyme A (Valeryl-CoA) is a short-chain fatty acyl-CoA that functions as an intermediate in mitochondrial β-oxidation and related metabolic pathways. Pentanoyl coenzyme A results from the formal condensation of the thiol group of coenzyme A with the carboxy group of pentanoic acid. Pentanoyl coenzyme A's levels can reflect changes in lipid metabolism under different physiological and pathological conditions. Pentanoyl coenzyme A can be used for research on lipid metabolism .

HY-150118

Lipid 8	Liposome	Others
Lipid 8 is an ionizable amino lipid that can be used to synthesize lipid nanoparticles (LNPs). Lipid 8 is applicable to research in drug delivery .

HY-159716

Lipid 50	Liposome	Others
Lipid 50 (compound 50) is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid 50 is a carrier for both siRNA and mRNA .

HY-U00319

Lipid peroxidation inhibitor 1	Reactive Oxygen Species (ROS)	Neurological Disease
Lipid peroxidation inhibitor 1 is a lipid peroxidation inhibitor with an IC₅₀ of 0.07 μM.

HY-159670

*Monophosphoryl Lipid* A-12** MPLA-12	Toll-like Receptor (TLR)	Inflammation/Immunology
Monophosphoryl Lipid A-12 (MPLA-12) is a Toll-like receptor 4 agonist. Monophosphoryl Lipid A-12 can be used for the research of immunization and vaccine .

HY-144002

RIBI-529 RC-529	Biochemical Assay Reagents	Inflammation/Immunology
RIBI-529 (RC-529), a lipid A mimetic (aminoalkyl glucosaminide 4-phosphate), is a adjuvant with a similar efficacy to MPL (Corixa). RIBI-529 signals through Toll-like receptor 4 to stimulate the innate immune system .

HY-173287

*LNP Lipid-48*	Liposome	Others
LNP Lipid-48 is an SM-102 analog used in the formation of lipid nanoparticles (LNPs).

HY-159858

Lipid 16	Liposome	Cancer
Lipid 16 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads. Lipid 16 as a potent cell type-specific ionizable lipid for the CD11bhi macrophage population without an additional targeting moiety .

HY-W698462

(S)-3-Hydroxymyristic acid (3S)-3-Hydroxytetradecanoic acid	Drug Isomer	Inflammation/Immunology
(S)-3-Hydroxymyristic acid ((3S)-3-Hydroxytetradecanoic acid) is the enantiomer of (R)-3-hydroxytetradecanoic acid (a lipid A component) (HY-W288375), and enhances the inherent immune adjuvant activity of lipid A .

HY-P3912A

Endotoxin inhibitor TFA	Interleukin Related	Infection
Endotoxin inhibitor TFA is a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor TFA inhibits the febrile response to LPS with very low toxicity and lethality .

HY-153376

*LNP Lipid-6*	Liposome	Others
LNP Lipid-6 (Compound Lipid 5) is an ionizable lipid (amino lipid). LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) .

HY-153375

*LNP Lipid-5*	Liposome	Others
LNP Lipid-5 (Compound Lipid 2) is an ionizable lipid (amino lipid). LNP Lipid-5 can be used to prepare lipid nanoparticles (LNP) .

HY-153187

*LNP Lipid-4*	Liposome	Others
LNP Lipid-4 (Compound 8-8) is a lipid compound. LNP Lipid-4 is involved in the synthesis of lipid nanoparticles compositions. LNP Lipid-4 has potential applications in the transportation of biologically active substances .

HY-153136

*LNP Lipid-1*	Liposome	Others
LNP Lipid-1 (Method B) is a lipid compound. LNP Lipid-1 is involved in the synthesis of lipid nanoparticles compositions. LNP Lipid-1 has potential applications in the transport of biologically active substances such as small molecule agents, proteins, and nucleic acids .

HY-150117

Lipid 6	Liposome	Others
Lipid 6 is an ionizable amino lipid. Lipid 6 can be used to synthesize lipid nanoparticles. Lipid 6 can be used in RNA delivery research .

HY-150116

Lipid 1	Liposome	Others
Lipid 1 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).

HY-156985

Lipid AX4	Isotope-Labeled Compounds Liposome	Others
Lipid AX4 is an ionizable cationic lipid with the _pK_a of 6.89， and can be used the study for the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo .

HY-D1412

LPd peroxida probe-1 1 Publications Verification	Ferroptosis	Others
LPd peroxida probe-1, a marker of ferroptosis, is a useful fluorescent probe for investigating the roles of lipid peroxidation in a variety of cell pathophysiologies. LPd peroxida probe-1 reduces lipid hydroperoxides to lipid alcohols and is used for imaging lipid hydroperoxides in living cells .

HY-159670B

*Monophosphoryl Lipid* A-12 triethylamine** MPLA-12 triethylamine	Toll-like Receptor (TLR)	Inflammation/Immunology
Monophosphoryl Lipid A-12 (triethylamine) is a toll-like receptor 4 agonist. Monophosphoryl Lipid A-12 (triethylamine) can be used for the research of immunization and vaccine .

HY-P3912

Endotoxin inhibitor	COX Interleukin Related	Infection
Endotoxin inhibitor a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor inhibits the febrile response to LPS with very low toxicity and lethality .

HY-E70266

Arachidoyl-CoA triammonium	Endogenous Metabolite	Metabolic Disease
Arachidoyl-CoA triammonium is a long-chain coenzyme A which formed by an esterification of a fatty alcohol and an activated fatty acid .

HY-131907

LpxC-IN-5	Bacterial	Infection
LpxC-IN-5 is a potent non-hydroxamate LpxC (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitor with an IC₅₀ of 20 nM. LpxC-IN-5 shows antibacterial activity against E. coli ATCC25922, P. aeruginosa ATCC27853, K. pneumoniae ATCC13883 and P. aeruginosa 5567 with MIC of 16, 4, 64, and 4 μg/mL, respectively .

HY-142992

*LNP Lipid-2*	Biochemical Assay Reagents Liposome	Others
LNP Lipid-2 is a lipid product can be used to deliver agents .

HY-176753

Lipid 20b	Liposome	Inflammation/Immunology
Lipid 20b is a thiophene ionizable cationic lipid. Lipid 20 b can be used to generate lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. Lipid 20b can be studied in research for enhancing mRNA vaccine delivery and transfection efficacy .

HY-156630A

*Ionizable lipid-1 hydrochloride*	Liposome	Others
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .

HY-N15786

*DSPE-RGD Lipid* sodium**	Biochemical Assay Reagents	Cancer
DSPE-RGD Lipid sodium is a lipid containing DSPE and RGD peptides that can be used to prepare lipid nanoparticles for drug delivery.

HY-N15803

*DOPE-RGD Lipid* sodium**	Biochemical Assay Reagents	Cancer
DOPE-RGD Lipid sodium is a lipid containing DOPE and RGD peptides that can be used to prepare lipid nanoparticles for drug delivery.

Cat. No.	Nombre del producto	Category	Target	Chemical Structure

HY-109506

DPPC 5+ Cited Publications 129Y83	Structural Classification Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Lipid Source Classification	Liposome Endogenous Metabolite
DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-113128A

sn-Glycerol 3-phosphate lithium	Productos naturales Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
sn-Glycerol 3-phosphate lithium is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate lithium from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate lithium for lipid metabolism .

HY-N0337

Eugenol,98% (stabilized with TBC) 5+ Cited Publications	Infection Structural Classification Monophenols Classification of Application Fields Phenols Piperaceae Plants Inflammation/Immunology Disease Research Fields Piper nigrum Linn. Source Classification	Environmental Pollutants Parasite Reactive Oxygen Species (ROS) Bacterial Apoptosis Ferroptosis
Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation.

HY-113128

sn-Glycerol 3-phosphate	Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Other Diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism .

HY-N3220

Myricetin 3-O-galactoside 1 Publications Verification	Flavonols Flavonoids Rhododendron dauricum Linn. Classification of Application Fields Phenols Polyphenols Metabolic Disease Ericaceae Plants Disease Research Fields Source Classification	Xanthine Oxidase
Myricetin 3-O-galactoside inhibits xanthine oxidase (XO) activity, lipid peroxidation and scavenges the free radical. Myricetin 3-O-galactoside inhibits lipid peroxidation with an IC₅₀ of 160 μg/mL. Antioxidant activity .

HY-N2427

Adamantane	Structural Classification Productos naturales Classification of Application Fields Psidium guajava Linn. Other Diseases Myrtaceae Plants Disease Research Fields	Others
Adamantane is a polycyclic cage molecule with high symmetry and remarkable properties. Adamantane can be incorporated into a lipophilic part of the lipid bilayer that constitutes membranes and as an anchor in the lipid bilayer of liposomes. Adamantane can be studied in pharmacological research to improve the lipophilicity and pharmacological properties of other active products .

HY-B1189

Meglutol Dicrotalic acid; 3-Hydroxy-3-methylglutaric acid	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification	HMG-CoA Reductase (HMGCR) Autophagy Endogenous Metabolite
Meglutol is a lipid-lowering agent. Meglutol can reduces cholesterol, triglycerides, serum β-lipoprotein, and phospholipids, and inhibits the activity of HMG-CoA reductase (a rate-limiting enzyme in cholesterol biosynthesis). Meglutol can induce significant lipid oxidative damage in brain tissue. It is promising for research in the field of cardiovascular diseases and metabolic diseases .

HY-N0261

Aurantio-obtusin 1 Publications Verification	Seeds of Cassia tora Linn. Cardiovascular Disease Classification of Application Fields Plants Quinones other families Leguminosae Anthraquinones Phenols Polyphenols Inflammation/Immunology Disease Research Fields Source Classification	TNF Receptor COX
Aurantio-obtusin is a anthraquinone compound that can be extracted from cassia seed. Aurantio-obtusin has the effects of decreasing blood pressure, decreasing blood lipids and anti-inflammatory.Aurantio-obtusin is an orally active vasodilator. Aurantio-obtusin ameliorates hepatic steatosis through AMPK/ autophagy- and AMPK/TFEB mediated inhibition of lipid accumulation .

HY-N8277

*Kdo2-Lipid* A ammonium** 3 Publications Verification	Productos naturales Microorganisms Classification of Application Fields Other Diseases Disease Research Fields Source Classification	Toll-like Receptor (TLR) TNF Receptor
Kdo2-Lipid A ammonium is a chemically defined lipopolysaccharide (LPS) with endotoxin activity equal to LPS. Kdo2-Lipid A ammonium is highly selective for TLR4. Kdo2-Lipid A ammonium stimulates the release of both TNF and PGE2 .

HY-N16040

DMG-pSar25	Structural Classification Lipid	Liposome
DMG-pSar25 is a double lipid-tailed polysarcosine lipid with 25 sarcosine moieties, serving as a PEG lipid substitute in lipid nanoparticle formulations for mRNA delivery. DMG-pSar25 supports mRNA delivery in lipid nanoparticle formulations .

HY-W013627

trans,trans-2,4-Decadienal	Productos naturales Microorganisms other families Classification of Application Fields Other Diseases Plants Disease Research Fields Source Classification	Apoptosis
trans,trans-2,4-Decadienal is a lipid peroxidation product of linolieic acid .

HY-N7390

Cholesterol glucuronide	Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Source Classification	Endogenous Metabolite
Cholesterol glucuronide is an endogenous metabolite of lipid generated in the liver by UDP glucuonyltransferase .

HY-N12762

DGTS	Structural Classification Microorganisms Lipid Source Classification	Liposome
DGTS, as described, is a structural isomer of DGTA and one of the most common betaine lipids found in microalgae, particularly abundant in Chlorophyceae . DGTS is a helper lipid that is structurally similar to DSPE or DOPE.

HY-113378R

3-Hydroxybutyric acid (Standard) β-Hydroxybutyric acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
3-Hydroxybutyric acid (Standard) is the analytical standard of 3-Hydroxybutyric acid. This product is intended for research and analytical applications. 3-Hydroxybutyric acid (β-Hydroxybutyric acid) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid can modulate the properties of membrane lipids[1].

HY-N7935

Procyanidin B5	Structural Classification Aronia melanocarpa Rosaceae Phenols Polyphenols Plants Source Classification	Reactive Oxygen Species (ROS)
Procyanidin B5 is an antioxidant with a IC₅₀ of 0.1 mM in lipid peroxidation assays using mouse liver homogenates. Procyanidin B5 scavenges superoxide anions and hydroxyl radicals, and inhibits lipid peroxidation. Procyanidin B5 can be used in research related to cardiovascular diseases, cancer, and malaria .

HY-113069

Decanoylcarnitine	Productos naturales Disease markers Endogenous metabolite Source Classification	Endogenous Metabolite
Decanoylcarnitine is a fatty ester lipid and an acylcarnitine derivative, which is a metabolite associated with impaired fatty acid metabolism in the elderly population .

HY-159670

*Monophosphoryl Lipid* A-12** MPLA-12	Lipid	Toll-like Receptor (TLR)
Monophosphoryl Lipid A-12 (MPLA-12) is a Toll-like receptor 4 agonist. Monophosphoryl Lipid A-12 can be used for the research of immunization and vaccine .

HY-N15971

DSPE-PEG(2000) Succinyl ammonium 2 Publications Verification	Structural Classification Lipid	Liposome
DSPE-PEG(2000) Succinyl ammonium is functionalized PEG lipid that can be used to synthesize lipid nanoparticles for drug delivery.

HY-N16032

Adipoyl-L-carnitine	Lipid	Biochemical Assay Reagents
Adipoyl-L-carnitine is an acyl carnitine lipid.

HY-N9610

Coenzyme Q6 Ubiquinone 30	Quinones Microorganisms Benzene Quinones Source Classification	Endogenous Metabolite
Coenzyme Q6 (Ubiquinone 30) is an isoprenylated benzoquinone lipid. Coenzyme Q6 exhibits functions in respiratory electron transport and as a lipid antioxidant. Coenzyme Q6 also has antioxidant effects, which can prevent the production of free radicals and oxidative damage .

HY-N16321

C18:0 DG-PEG2K-triGalNAc	Lipid	Biochemical Assay Reagents
C18:0 DG-PEG2K-triGalNAc is a functionalized PEG lipid that consists of a C18:0 DG unit conjugated to a triGalNAc. C18:0 DG-PEG2K-triGalNAc can be used to prepare lipid nanoparticles for drug delivery.

HY-142099

Hispaglabridin A	Structural Classification Flavonoids Leguminosae Plants Glycyrrhiza uralensis Fisch. Isoflavones Source Classification	Reactive Oxygen Species (ROS)
Hispaglabridin A is an isoflavone derivative extracted from licorice roots. Hispaglabridin A is an antioxidant that is effective at inhibiting lipid peroxidation .

HY-N16289

DSPE-PEG8 Maleimide sodium	Lipid	Biochemical Assay Reagents
DSPE-PEG8 Maleimide sodium is a PEG lipid containing DSPE, a polyethylene glycol chain consisting of eight ethylene glycol units (PEG8), and a maleimide group (Mal). DSPE-PEG8 Maleimide sodium can be used to prepare lipid nanoparticles for drug delivery .

HY-N16231

3A-MPLA ammonium	Lipid	Toll-like Receptor (TLR)
3A-MPLA ammonium, a monophosphoryl rri-acyl lipid A, is a TLR-4 agonist .

HY-N15786

*DSPE-RGD Lipid* sodium**	Lipid	Biochemical Assay Reagents
DSPE-RGD Lipid sodium is a lipid containing DSPE and RGD peptides that can be used to prepare lipid nanoparticles for drug delivery.

HY-N15803

*DOPE-RGD Lipid* sodium**	Lipid	Biochemical Assay Reagents
DOPE-RGD Lipid sodium is a lipid containing DOPE and RGD peptides that can be used to prepare lipid nanoparticles for drug delivery.

HY-N15984

18:1-12:0 Biotin PC	Structural Classification Lipid	Liposome
18:1-12:0 Biotin PC can be used in lipid blot analysis for studying the interactions of Niemann-Pick C2 (NPC2)-lipid. 18:1-12:0 Biotin PC is also used to prepare liposomes.

HY-N15837

DSPE-PEG(2000)-N-Triphenylphosphonium	Lipid	Biochemical Assay Reagents
DSPE-PEG(2000)-N-Triphenylphosphonium is functionalized PEG lipid that can be used to synthesize lipid nanoparticles for drug delivery.

HY-N16318

CP-LC-1067	Lipid	Biochemical Assay Reagents
CP-LC-1067 is a certest lipid.

HY-N15923

Anteiso 15:0 fatty acid	Lipid	Biochemical Assay Reagents
Anteiso 15:0 fatty acid is a branched lipid.

HY-N16291

DSG-pSar25-Maleimide	Structural Classification Lipid	Biochemical Assay Reagents
DSG-pSar25-Maleimide is a lipid that is composed of a DSG unit conjugated to a pSar25 polymer. DSG-pSar25-Maleimide can be used to prepare lipid nanoparticles for drug delivery.

HY-N15799

trans-AzCA4	Lipid	Biochemical Assay Reagents
trans-AzCA4 is a photoswitchable lipid .

HY-N15978

18:1-12:0 Biotin PIP3 tetrasodium	Lipid	Biochemical Assay Reagents
18:1-12:0 Biotin PIP3 tetrasodium is a biotinylated lipid.

HY-N15908

18:0 PEG2000 PE CF ammonium	Lipid	Fluorescent Dye
18:0 PEG2000 PE CF ammonium is a fluorescent PEG lipid.

HY-N15997

14:0-14:0(COOH) PC DMPC-COOH	Lipid	Biochemical Assay Reagents
14:0-14:0(COOH) PC is a lipid for supported monolayer.

HY-N15817

16:0 PA-PEG3-Mannose ammonium	Lipid	Biochemical Assay Reagents
16:0 PA-PEG3-Mannose ammonium is a functionalized lipid.

HY-N15884

NBD Palmitic acid	Lipid	Fluorescent Dye
NBD Palmitic Acid is a fluorescent lipid containing Palmitic acid (HY-N0830) .

HY-N8466

(-)-Lyoniresinol 9'-O-glucoside	Albizia julibrissin Durazz. Leguminosae Plants Saccharides Monosaccharides Source Classification	Reactive Oxygen Species (ROS)
(-)-Lyoniresinol 9'-O-glucoside is an inhibitor of ROS. (-)-Lyoniresinol 9'-O-glucoside reduces lipid accumulation and lipid metabolic disorders in FFAs-exposed HepG2 cells. (-)-Lyoniresinol 9'-O-glucoside inhibits high glucose-induced reactive oxygen species production .

HY-N2159

Lancerin 1 Publications Verification	Xanthones Classification of Application Fields Polygalaceae Phenols Polyphenols Metabolic Disease Plants Polygala tenuifolia Willd. Disease Research Fields Source Classification	Others
Lancerin, isolated from the root bark of Cudraniu cochinchinensis, possesses anti-lipid peroxidation .

HY-113128B

sn-Glycerol 3-phosphate biscyclohexylammonium salt	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
sn-Glycerol 3-phosphate biscyclohexylammonium salt is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate biscyclohexylammonium salt from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate biscyclohexylammonium salt for lipid metabolism .

HY-N16301

Lipid A (14:0(5)-cyclopropyl17:0(1)) diammonium	Lipid	Biochemical Assay Reagents
Lipid A (14:0(5)-cyclopropyl17:0(1)) diammonium, a lipid, is an adjuvant. Lipid A (14:0(5)-cyclopropyl17:0(1)) diammonium has immunostimulatory properties.

HY-N15852

APL-719	Lipid	Biochemical Assay Reagents
APL-719 is a cationic lipid that can be used to synthesize lipid nanoparticles for drug delivery.

HY-N15882

16:0 DNP Cap PE monoammonium	Lipid	Biochemical Assay Reagents
16:0 DNP Cap PE monoammonium is an antigenic lipid that plays a role in promoting antigen presentation on lipid bilayers .

HY-N15951

C16 Ceramide-suc-PEG2K-maleimide	Lipid	Biochemical Assay Reagents
C16 Ceramide-suc-PEG2K-maleimide is functionalized PEG lipid that can be used to synthesize lipid nanoparticles for drug delivery.

HY-N15992

POBPC	Lipid	Biochemical Assay Reagents
POBPC is a oxidized lipid.

HY-N16319

DSG-pSar25	Lipid	Biochemical Assay Reagents
DSG-pSar25 is a lipid conjugated to DSG and pSar25 polymer. DSG-pSar25 can be used to prepare lipid nanoparticles for drug delivery.

HY-N12440

Sarmenoside II	Crassulaceae Sedum sarmentosum Bunge Phenols Polyphenols Plants Source Classification	Others
Sarmenoside II is a flavonol glycoside with activity that inhibits lipid accumulation. Sarmenoside II inhibits albumin-oleate-induced lipid accumulation in HepG2 cells by approximately 30% at 100 μM.

HY-N16041

N-Octadecyl-pSar25	Lipid	Biochemical Assay Reagents
N-Octadecyl-pSar25 is a lipid that is composed of a N-octadecyl unit conjugated to a pSar25 polymer. N-Octadecyl-pSar25 can be used to synthesize lipid nanoparticles for drug delivery.

HY-N16037

N-Dodecyl-pSar25	Lipid	Biochemical Assay Reagents
N-Dodecyl-pSar25 is a lipid that is composed of a N-dodecyl unit conjugated to a pSar25 polymer. N-Dodecyl-pSar25 can be used to synthesize lipid nanoparticles for drug delivery.

HY-N15832

PacFA L-carnitine	Lipid	Biochemical Assay Reagents
pacFA L-carnitine is an acyl carnitine lipid.

Cat. No.	Nombre del producto	Chemical Structure

HY-W040193S

DSPC-d70
DSPC-d₇₀ (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₇₀) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .

HY-B2130S1

Uric acid-15N2
Uric acid- ¹⁵N₂ is the ¹⁵N labeled Uric acid . Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation .

HY-113147AS

L-Palmitoylcarnitine-d3 hydrochloride

L-Palmitoylcarnitine-d₃ hydrochloride is the deuterium labeled L-Palmitoylcarnitine hydrochloride. L-Palmitoylcarnitine hydrochloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine hydrochloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2 .

HY-W010452S1

3-Hydroxybutyric acid-13C4 sodium
3-Hydroxybutyric acid- ¹³C₄ sodium is the ¹³C labeled 3-Hydroxybutyric acid sodium (HY-W010452). 3-Hydroxybutyric acid sodium is a metabolite that is elevated in type I diabetes, and can modulate the properties of membrane lipids .

HY-113378S

3-Hydroxybutyric acid-d4 sodium
3-Hydroxybutyric acid-d₄ (sodium) is the deuterium labeled 3-Hydroxybutyric acid. 3-Hydroxybutyric acid (β-Hydroxybutyric acid) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid can modulate the properties of membrane lipids .

HY-W040193S3

DSPC-d83
DSPC-d₈₃ (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₈₃) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .

HY-N0337S

Eugenol-d3
Eugenol-d₃ is the deuterium labeled Eugenol. Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation.

HY-136490S

Psychosine-d5
Psychosine-d₅ is deuterium labeled Psychosine. Psychosine, a substrate of the galactocerebrosidase (GALC) enzyme, is a potential biomarker for Krabbe disease. Psychosine is a highly cytotoxic lipid, capable of inducing cell death in a wide variety of cell.

HY-B0430S

Pantothenic acid-13C3,15N hemicalcium
Pantothenic acid- ¹³C₃, ¹⁵N (hemicalcium) is the ¹³C-labeled and ¹⁵N-labeled D-Pantothenic acid. D-Pantothenic acid is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA). D-Pantothenic acid plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism .

HY-B2130S

Uric acid-13C,15N3
Uric acid- ¹³C, ¹⁵N₃ is the ¹³C-labeled and ¹⁵N-labeled Uric acid. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation .

HY-14520S

Tetrahydrofolic acid-d4

Tetrahydrofolic acid-d₄ is the deuterium labeled Tetrahydrofolic acid. Tetrahydrofolic acid (L-5,6,7,8-Tetrahydrofolic acid) is the biologically active vitamin B9 folate derivative. Tetrahydrofolic acid is a donor of one-carbon groups for amino acids, nucleic acids, and lipids. Tetrahydrofolic acid serves as an acceptor of free formaldehyde, producing 5,10-methylenetetrahydrofolate-Tetrahydrofolic acid .

HY-134541S6

SM-102-d4
SM-102-d₄ is the deuterium labeled SM-102 (HY-134541). SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-N0733S3

Glucosamine-6-13C hydrochloride
Glucosamine-6- ¹³C (hydrochloride) is the ¹³C labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as

HY-B1411S

i-Inositol-d6
i-Inositol-d₆ is the deuterium labeled i-Inositol. i-Inositol is a chemical compound, associated lipids are found in many foods, in particular fruit, especially cantaloupe and oranges.

HY-B0589S

Atorvastatin-d5 hemicalcium
Atorvastatin-d₅ (hemicalcium) is the deuterium labeled Atorvastatin. Atorvastatin hemicalcium is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin hemicalcium inhibits human SV-SMC proliferation and invasion with IC₅₀s of 0.39 μM and 2.39 μM, respectively .

HY-113217S

Cholesteryl oleate-d7

Cholesteryl oleate-d₇ is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing .

HY-B0006S1

Carvedilol-d4
Carvedilol-d₄ is the deuterium labeled Carvedilol. Carvedilol (BM 14190) is a non-selective β/α-1 blocker . Carvedilol inhibits lipid peroxidation in a dose-dependent manner with an IC₅₀ of 5 μM. Carvedilol is a multiple action antihypertensive agent with potential use in angina and congestive heart failure . Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome .

HY-N0733S

Glucosamine-13C hydrochloride
Glucosamine- ¹³C (hydrochloride) is the ¹³C labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a

HY-W770183

Uric acid-13C3
Uric acid- ¹³C₃ is ¹³C-labeled Uric acid (HY-B2130). Uric acid is the end product of purine metabolism in the human body. Uric acid can scavenge reactive oxygen species (ROS), such as singlet oxygen and peroxynitrite, and inhibit lipid peroxidation.

HY-112251S

D-Lin-MC3-DMA-13C3
D-Lin-MC3-DMA- ¹³C₃ is the ¹³C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle .

HY-B0258S

Gemfibrozil-d6
Gemfibrozil-d₆ is the deuterium labeled Gemfibrozil. Gemfibrozil is an activator of PPAR-α, used as a lipid-lowering agent; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively.

HY-N2427S

Adamantane-d16
Adamantane-d₁₆is the deuterium labeled Adamantane (HY-N2427). Adamantane, a polycyclic cage molecule with high symmetry and remarkable properties. Adamantane can be incorporated into a lipophilic part of the lipid bilayer that constitutes membranes and as an anchor in the lipid bilayer of liposomes. Adamantane can be used in research of surface recognition and drug delivery .

HY-136490S1

Psychosine-d7
Psychosine-d₇ is deuterium labeled Psychosine. Psychosine, a substrate of the galactocerebrosidase (GALC) enzyme, is a potential biomarker for Krabbe disease. Psychosine is a highly cytotoxic lipid, capable of inducing cell death in a wide variety of cell

HY-N7264S

7α-Hydroxycholesterol-d7
7α-Hydroxycholesterol-d₇ is the deuterium labeled 7α-Hydroxycholesterol. 7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation .

HY-141629S2

N-Palmitoyl-D-sphingomyelin-d9
N-Palmitoyl-D-sphingomyelin-d₉ (Sphingomyelin 16:0-d₉) is deuterium labeled N-Palmitoyl-D-sphingomyelin. N-Palmitoyl-D-sphingomyelin (Sphingomyelin 16:0) (Compound SM-03) can be used for the synthesis of lipid nanoparticles .

HY-B0589S1

Atorvastatin-d5 sodium
Atorvastatin-d₅ (sodium) is the deuterium labeled Atorvastatin sodium. Atorvastatin sodium is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin sodium inhibits human SV-SMC proliferation and invasion with IC₅₀s of 0.39 μM and 2.39 μM, respectively .

HY-W015851S

3-Hydroxybutanoic acid-13C sodium
3-Hydroxybutanoic acid-13C- ¹³C (sodium) is the ¹³C labeled 3-Hydroxybutanoic acid sodium (HY-W010452). 3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid sodium can modulate the properties of membrane lipids .

HY-W012241S1

Dodecanedioic acid-d4

Dodecanedioic acid-d₄ is the deuterium labeled Dodecanedioic acid (HY-W012241). Dodecanedioic acid is an orally active straight-chain dicarboxylic acid. As an alternative energy substrate between lipids and carbohydrates, Dodecanedioic acid can be rapidly oxidized during exercise, reducing muscle fatigue without stimulating insulin secretion. Dodecanedioic acid also exhibits blood glucose-lowering activity in non-insulin-dependent diabetes mellitus .

HY-109506S9

DPPC-13C2 1 Publications Verification
DPPC-13C2 is a deuterated labeled DPPC . DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-N0733S4

Glucosamine-15N hydrochloride
Glucosamine- ¹⁵N (hydrochloride) is the ¹⁵N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a

HY-N0733S1

Glucosamine-2-13C hydrochloride
Glucosamine-2- ¹³C (hydrochloride) is the ¹³C labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as

HY-N0733S2

Glucosamine-13C,15N hydrochloride
Glucosamine- ¹³C, ¹⁵N (hydrochloride) is the ¹³C and ¹⁵N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, i

HY-N0733S5

Glucosamine-13C6,15N hydrochloride
Glucosamine- ¹³C₆, ¹⁵N hydrochloride is the ¹³C and ¹⁵N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids.

HY-W010452S2

3-Hydroxybutyric acid-13C2 sodium
3-Hydroxybutyric acid- ¹³C₂ (sodium) is the ¹³C labeled 3-Hydroxybutyric acid sodium (HY-W010452). 3-Hydroxybutyric acid sodium is a metabolite that is elevated in type I diabetes, and can modulate the properties of membrane lipids .

HY-109541S1

Colfosceril miristate-d4
Colfosceril miristate-d₄ (DMPC-d₄) is deuterium labeled Colfosceril miristate. Colfosceril miristate is a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery .

HY-B0222S

1-Docosanol-d45
1-Docosanol-d₄₅ is the deuterium labeled 1-Docosanol. 1-Docosanol is a saturated fatty alcohol used traditionally as an emollient, emulsifier, and thickener in cosmetics, and nutritional supplement. 1-Docosanol is an inhibitor of lipid-enveloped viruses including herpes simplex.

HY-13417S

AICAR-13C2,15N
AICAR- ¹³C₂, ¹⁵N (Acadesine- ¹³C₂, ¹⁵N; AICA Riboside- ¹³C₂, ¹⁵N) is the ¹³C and ¹⁵N labeled AICAR (HY-13417) . AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor .

HY-W040193S1

DSPC-d74
DSPC-d₇₄ (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₇₄) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .

HY-W040193S6

DSPC-d13
DSPC-d₁₃ (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₁₃) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .

HY-W040193S2

DSPC-d79
DSPC-d₇₉ (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₇₉) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .

HY-W040193S5

DSPC-d9
DSPC-d₉ (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₉) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .

HY-W040193S4

DSPC-d4
DSPC-d₄ (1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d₄) is the deuterium labeled DSPC (HY-W040193). DSPC is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .

HY-109506S2

(Rac)-DPPC-d6
(Rac)-DPPC-d6 is a deuterated labeled DPPC . DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-B1858S

Isoprothiolane-d4

Isoprothiolane-d₄ is the deuterium labeled Isoprothiolane (HY-B1858). Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver .

HY-109506S10

DPPC-13C3
DPPC- ¹³C₃ (129Y83- ¹³C) is the ¹³C-labeled DPPC (HY-109506). DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-113217S1

Cholesteryl oleate-d7-1

Cholesteryl oleate-d₇-1 is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing .

HY-W747751

Sorbic acid-13C2

Sorbic acid- ¹³C₂ is the ¹³C-labeled Sorbic acid (HY-N0626). Sorbic acid is an effective, safe, and non-toxic food preservative. It can effectively inhibit most molds, yeasts, and certain bacteria. Sorbic acid is orally active and can enhance the growth performance of economically important animals (Duroc × Landrace × Yorkshire piglets) by activating the insulin-like growth factor system (IGF), and it can also lead to lipid accumulation by disrupting lipid clearance pathways .

HY-138166S

Rosuvastatin lactone-d6

Rosuvastatin lactone-d₆ is the deuterium labeled Rosuvastatin lactone. Rosuvastatin lactone is a metabolite of Rosuvastatin (HY-17504A), a statin lipid-lowering agent and HMG-CoA inhibitor. Rosuvastatin lactone exhibits endothelium-independent and HMG-CoA reductase-independent vasorelaxant activity in rat aortic rings, and its vasorelaxant effect is jointly mediated by NO produced by inducible nitric oxide synthase (iNOS) located in vascular smooth muscle and activation of potassium channels. Rosuvastatin lactone itself has no lipid-lowering effect .

HY-146925S

15:0 Lyso PC-d5

15:0 Lyso PC-d₅ is deuterium labeled 15:0 Lyso PC (HY-W329357). 15:0 Lyso PC is a lysophosphatidylcholine (Lyso PC), a product of phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine (PC) and is involved in cell membrane remodeling and inflammatory signaling. 15:0 Lyso PC demonstrates significant lipid metabolism disturbances in the serum of patients with ischemic heart disease (IHD) and ischemic cardiomyopathy (ICM). 15:0 Lyso PC can be used as a lipid biomarker for cardiovascular disease.

HY-113369S

Cholesteryl arachidonate-d8
Cholesteryl arachidonate-d₈ is deuterium labeled Cholesteryl arachidonate (HY-113369). Cholesteryl arachidonate, a lipid, is an endogenous metabolite. Cholesteryl arachidonate has antibacterial activity .

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-134541G

SM-102	Liposome	Infection
SM-102 (GMP) is SM-102 (HY-134541) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-134541GL

SM-102 (GMP Like)	Liposome	Infection
SM-102 (GMP Like) is SM-102 (HY-134541) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .

HY-W040193GL

DSPC (GMP Like) 1,2-Distearoyl-sn-glycero-3-PC (GMP Like); 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (GMP Like)	Liposome	Others
DSPC (GMP Like) (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is DSPC (HY-W040193) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .

HY-112754AGL

DOTAP chloride (GMP Like) 1,2-Dioleoyl-3-trimethylammonium-propane chloride (GMP Like)	Liposome	Others
DOTAP chloride (GMP Like) is the GMP Like class DOTAP chloride (HY-112754A). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOTAP chloride is a cationic lipid with good membrane fusion ability and biocompatibility. DOTAP chloride (GMP Like) can be used as an excipient for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) without the use of helper lipid .

HY-138170GL

ALC-0315 (GMP Like)	Liposome SARS-CoV	Infection
ALC-0315 (GMP Like) is ALC-0315 (HY-138170) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .

HY-138300GL

ALC-0159 (GMP Like)	Liposome	Inflammation/Immunology
ALC-0159 (GMP Like) is the GMP Like class ALC-0159 (HY-138300). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. ALC-0159, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient .

HY-112005GL

DOPE (GMP Like) Dioleoylphosphatidylethanolamine (GMP Like); 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (GMP Like)	Liposome Endogenous Metabolite	Inflammation/Immunology
DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .

HY-112251GL

D-Lin-MC3-DMA (GMP Like)	Liposome	Cancer
D-Lin-MC3-DMA (GMP Like) is the GMP Like class D-Lin-MC3-DMA (HY-112251). GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.

HY-112764GL

DMG-PEG 2000 (GMP Like)	Liposome	Metabolic Disease
DMG-PEG 2000 (GMP Like) is DMG-PEG 2000 (HY-112764) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .

HY-107413G

SR11237	RAR/RXR Tyrosine Hydroxylase	Neurological Disease Inflammation/Immunology
SR11237 GMP is SR11237 (HY-107413) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SR11237 is a RXR activator and lipid metabolism regulator that promotes the differentiation of induced neural stem cells into dopaminergic (TH-positive) neurons. SR11237 induces transcriptional regulation of lipogenic genes and cholesterol transporters, increases glycosaminoglycan release, and elevates total cellular triglyceride levels. SR11237 promotes heterodimerization of RXR with Nurr1, thereby enhancing tyrosine hydroxylase expression and facilitating dopamine release. SR11237 produces a synergistic effect when used in combination with bFGF/EGF. SR11237 is mainly used in studies related to osteoarthritis and Parkinson's disease .

HY-112005G

DOPE Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine	Ferroptosis Glutathione Peroxidase ACSL Family Amino acid Transporter	Neurological Disease Inflammation/Immunology
DOPE GMP is DOPE (HY-112005) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOPE (Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) is an orally active inhibitor of ferroptosis with anti-inflammatory and intestinal barrier maintenance activities. DOPE regulates the expression of ACSL4, SLC7A11 and GPX4 to restore the redox system balance, thereby reducing the levels of lipid peroxides, iron ions and intestinal inflammatory factors (IL-1β and IL-6). DOPE promotes the migration and proliferation of intestinal epithelial cells and increases the level of tight junction proteins; it also destabilizes endosomal membranes, mediates the conjugation of RVG peptides with mesenchymal stem cell-derived exosomes to enhance brain targeting. DOPE can be applied to research related to neonatal necrotizing enterocolitis and Alzheimer's disease .

HY-107614G

1-Oleoyl lysophosphatidic acid sodium 1-Oleoyl-sn-glycero-3-phosphate sodium; 1-Oleoyl-LPA sodium	LPL Receptor ROCK TGF-beta/Smad TGF-β Receptor	Neurological Disease Cancer
1-Oleoyl lysophosphatidic acid sodium (GMP) is the GMP-grade form of 1-Oleoyl lysophosphatidic acid sodium (HY-107614). GMP-grade small molecules serve as auxiliary reagents in cell therapy. 1-Oleoyl lysophosphatidic acid sodium is a bioactive lipid signaling molecule. 1-Oleoyl lysophosphatidic acid sodium inhibits lysoPLD-catalyzed hydrolysis of lysophosphatidylcholine and FS-3. 1-Oleoyl lysophosphatidic acid sodium activates LPA₁ and LPA₂, thereby triggering calcium mobilization, NFATc1 translocation, Rho/ROCK activation, Smad2/3 phosphorylation and c-Fos expression. 1-Oleoyl lysophosphatidic acid sodium induces anxiety-like, depression-like and hypoactivity phenotypes, regulates osteoclast cytoskeleton and viability, reduces osteoclast bone resorptive activity, and drives mesenchymal stem cell differentiation into myofibroblast-like cells. 1-Oleoyl lysophosphatidic acid sodium stimulates the secretion of transforming growth factor-β1 and stromal cell-derived factor-1. 1-Oleoyl lysophosphatidic acid sodium is applicable to research related to anxiety, depression and ovarian cancer .

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