Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
long non-coding RNA
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "long non-coding RNA" in MCE Product Catalog:
Cat. No.: HY-148688
Purity: 96.25%
Target:
Research Areas:
ASO 556089 sodium is a 16 nucleotide length gapmer (3-10-3) that targets the human and mouse long non-coding RNA MALAT1, with the sequence: 5’-GmCATTmCTAATAGmCAGmC-3’ .
0 Images
ION-626112 (sodium)
Cat. No.: HY-159693A
Synonyms: ION-626112 sodium
0 Images
ION-626112
Cat. No.: HY-159693
CAS No.: 2091995-55-8
Synonyms: ION-626112
Cat. No.: HY-162384
CAS No.: 3034959-68-4
Target:
Research Areas:
EPIC-0628 is an inhibitor of the HOTAIR-EZH2 interaction and promotes ATF3 expression. The long noncoding RNA HOTAIR has been found to regulate glioblastoma (GBM) progression and mediate DNA damage repair (DDR) by interacting with the catalytic subunit EZH2 of PRC2. EPIC-0628 also inhibits the ATF3-p38-E2F1 DDR pathway to inhibit the HR pathway and upregulates CDKN1A (p21) expression, causing cell cycle arrest. EPIC-0628 also synergizes with Temozolomide (TMZ) (HY-17364) to enhance its in vivo potency .
Cat. No.: HY-175604
CAS No.: 1061105-16-5
Target:
Research Areas:
SCL-1 is an orally active anti-PD-1/PD-L1 inhibitor. SCL-1 can inhibit PD-1/PD-L1 binding. SCL-1 increases T cells, B cells and natural killer cells. SCL-1 exerts strong tumor growth inhibitory effects that were mediated by effector T-cell induction inside tumors and the up-regulated expression of long non-coding RNAs as neoantigens leading to cytotoxic T lymphocyte activation. SCL-1 can be used for the research of cancer, such as triple-negative breast cancer .
Cat. No.: HY-148688H
Target:
Research Areas:
ASO 556089 (with PS modification) sodium is the PS-modified version of ASO 556089 (HY-148688). ASO 556089 sodium is a 16 nucleotide length gapmer (3-10-3) that targets the human and mouse long non-coding RNA MALAT1, with the sequence: 5’-GmCATTmCTAATAGmCAGmC-3’ .
Cat. No.: HY-190809
Target:
Research Areas:
Anticancer agent-371 is an anticancer compound that exerts antiproliferative and cytotoxic activity by inhibiting ABCC2 efflux transporter expression, inducing the integrated stress response and ER stress/unfolded protein response pathways, promoting amino acid deprivation and metabolic stress signaling, and reprogramming the long non-coding RNA landscape; it exhibits low toxicity to normal cells and can be used for research on pancreatic cancer, breast cancer, colorectal cancer, liver cancer, and ovarian cancer .
Cat. No.: HY-P73024
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EFNA1; GMAN; Prev. TNFAIP4; Tumor Necrosis Factor Alpha-Induced Protein 4; Prev. EPLG1; TNF Alpha-Induced Protein 4; EPH-Related Receptor Tyrosine Kinase Ligand 1; LERK-1; Ephrin-A1; Tumor Necrosis Factor, Alpha-Induced Protein 4; LERK1; Epididymis Secretory Sperm Binding Protein; Immediate Early Response Protein B61; Ligand Of Eph-Related Kinase 1; ECKLG; B61; Ephrin A1; Gastric Cancer Metastasis Associated long noncoding RNA
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P70373
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EFNA1; GMAN; Prev. TNFAIP4; Tumor Necrosis Factor Alpha-Induced Protein 4; Prev. EPLG1; TNF Alpha-Induced Protein 4; EPH-Related Receptor Tyrosine Kinase Ligand 1; LERK-1; Ephrin-A1; Tumor Necrosis Factor, Alpha-Induced Protein 4; LERK1; Epididymis Secretory Sperm Binding Protein; Immediate Early Response Protein B61; Ligand Of Eph-Related Kinase 1; ECKLG; B61; Ephrin A1; Gastric Cancer Metastasis Associated long noncoding RNA
Species:
Mouse
Source:
HEK293
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
