4 Results for "

matriptase-2

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "matriptase-2" in MCE Product Catalog:

Art. -Nr.: HY-130136A
Target:  

Ser/Thr Protease

Forschungsgebiete:  

Others

TMPRSS6-IN-1 (TFA) is a potent inhibitor of TMPRSS6 (Matriptase-2), belonging to TTSPs (transmembrane serine protease). TMPRSS6, is a type II TTSP, the genetic reduction of which will improve symptoms of hemochromatosis and beta thalassemia in mice .
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Art. -Nr.: HY-130136
CAS. Nr.: 2088415-78-3
Target:  

Ser/Thr Protease

Forschungsgebiete:  

Others

TMPRSS6-IN-1 (compound 8) is a potent inhibitor of TMPRSS6 (Matriptase-2), belonging to TTSPs (transmembrane serine protease). TMPRSS6, is a type II TTSP, the genetic reduction of which will improve symptoms of hemochromatosis and beta thalassemia in mice .
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Art. -Nr.: HY-P89613
Synonyms: UNQ354/PRO618, TMPRSS6, Transmembrane protease serine 6, matriptase-2

Host:  

Mouse

Application:  

WB, ICC/IF, IF-Tissue, IP, ELISA

Reactivity:  

human

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Art. -Nr.: HY-P992451
Synonyms: KY1066
RLYB331 (KY1066) is a is a monoclonal antibody targeting Matriptase-2 (TMPRSS6) . RLYB331 binds to the serine protease active site of matriptase-2, blocking protease activity to increase hepcidin expression. RLYB331 reduces iron overload, inhibits α-aggregates, reduces ROS, inhibits apoptosis, and enhances erythroid differentiation. RLYB331 ameliorates ineffective erythropoiesis in β-thalassemic mouse models. RLYB331 can be used for the research of β-thalassemia [2].
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