TMPRSS6-IN-1 TFA
Based on 1 Customer Validation
TMPRSS6-IN-1 (TFA) is a potent inhibitor of TMPRSS6 (Matriptase-2), belonging to TTSPs (transmembrane serine protease). TMPRSS6, is a type II TTSP, the genetic reduction of which will improve symptoms of hemochromatosis and beta thalassemia in mice.
For research use only. We do not sell to patients.
- Formula: C35H41F3N8O6S2
- Molecular Weight:790.88
-
Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Chemical Information
-
Appearance Solid
-
Molecular Weight 790.88
-
Formula C35H41F3N8O6S2
-
SMILES
NC(NCCC[C@H](NC([C@@H](NC([C@@H](NC(CCC1=CC=CC=C1)=O)CC2=CSC=N2)=O)C(C)C)=O)C(C3=NC4=C(S3)C=CC=C4)=O)=N.OC(C(F)(F)F)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 125 mg/mL (158.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (269 KB)
-
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2644 mL | 6.3221 mL | 12.6441 mL | 31.6104 mL |
| 5 mM | 0.2529 mL | 1.2644 mL | 2.5288 mL | 6.3221 mL | |
| 10 mM | 0.1264 mL | 0.6322 mL | 1.2644 mL | 3.1610 mL | |
| 15 mM | 0.0843 mL | 0.4215 mL | 0.8429 mL | 2.1074 mL | |
| 20 mM | 0.0632 mL | 0.3161 mL | 0.6322 mL | 1.5805 mL | |
| 25 mM | 0.0506 mL | 0.2529 mL | 0.5058 mL | 1.2644 mL | |
| 30 mM | 0.0421 mL | 0.2107 mL | 0.4215 mL | 1.0537 mL | |
| 40 mM | 0.0316 mL | 0.1581 mL | 0.3161 mL | 0.7903 mL | |
| 50 mM | 0.0253 mL | 0.1264 mL | 0.2529 mL | 0.6322 mL | |
| 60 mM | 0.0211 mL | 0.1054 mL | 0.2107 mL | 0.5268 mL | |
| 80 mM | 0.0158 mL | 0.0790 mL | 0.1581 mL | 0.3951 mL | |
| 100 mM | 0.0126 mL | 0.0632 mL | 0.1264 mL | 0.3161 mL |
TMPRSS6-IN-1 TFA Related Classifications
HY-130136A Related Classifications
Powered by Bioz