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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
molecular ion
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "molecular ion" in MCE Product Catalog:
10
10 Publications Verification
Cat. No.: HY-B1610N
5
5 Cited Publications
Synonyms: 2-Morpholinoethanesulphonic acid
5
5 Cited Publications
Cat. No.: HY-D0858A
CAS No.: 145224-94-8
Synonyms: 2-Morpholinoethanesulphonic acid monohydrate
5
5 Cited Publications
Cat. No.: HY-D0858C
CAS No.: 1266615-59-1
Synonyms: 2-Morpholinoethanesulphonic acid hydrate
5
5 Cited Publications
Cat. No.: HY-D0858E
CAS No.: 39946-25-3
Synonyms: 2-Morpholinoethanesulphonic acid potassium
5
5 Cited Publications
Cat. No.: HY-D0858B
CAS No.: 71119-23-8
Synonyms: 2-Morpholinoethanesulphonic acid sodium salt
5
5 Cited Publications
Cat. No.: HY-D0858D
CAS No.: 117961-21-4
Synonyms: 2-Morpholinoethanesulphonic acid hemisodium
1
1 Cited Publications
Cat. No.: HY-W019981B
CAS No.: 7791-18-6
Synonyms: MgCl2 hexahydrate, for molecular biology
1
Target:
Research Areas:
DOTA-tris(tBu)ester NHS ester is a bifunctional precursor to a DOTA-based chelating agent. DOTA-tris(tBu)ester NHS ester can be used to label primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules, and upon deprotection forms stable complexes with metal ions for applications in molecular imaging .
Cat. No.: HY-W088069
CAS No.: 16788-57-1
Target:
Research Areas:
Dipotassium hydrogen phosphate trihydrate, which is commonly used as a buffer and source of phosphorus and potassium in various applications, such as fertilizers, food processing, and pharmaceuticals, in biochemistry and molecular biology, Dipotassium hydrogen phosphate trihydrate is used in the preparation of cell culture media And reagent buffer system, in addition, it has been used in analytical chemistry as a reagent for the determination of calcium and magnesium ions in water samples.
Cat. No.: HY-D0858S
CAS No.: 352534-94-2
Cat. No.: HY-D0858AR
CAS No.: 145224-94-8
Synonyms: 2-Morpholinoethanesulphonic acid monohydrate (Standard)
Cat. No.: HY-118967
CAS No.: 663212-40-6
Synonyms: VU0183254
Target:
Research Areas:
VUANT1 (VU0183254) is an allosteric antagonist of insect odorant receptor ion channels, which has the activity of inhibiting insect odorant receptor signaling. VUANT1 can inhibit the activation of insect odorant receptors through allosteric regulation, which is important for the study of the molecular mechanism of insect olfactory signaling. Although it may be of limited use in insect control programs, it can be used as a pharmacological tool to study related mechanisms.
Cat. No.: HY-101238R
CAS No.: 2482-00-0
Category:
Cat. No.: HY-101238S
CAS No.: 909556-32-7
Cat. No.: HY-101238SA
Research Areas:
Agmatine-d8 hydrochloride is the deuterated-labeled Agmatine-d8 hydrochloride. Agmatine hydrochloride exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor .
Cat. No.: HY-L923
9000 compounds
Ion channels are key proteins on the cell membrane that regulate the flow of ions across membranes. They participate in nearly all physiological processes, including nerve conduction, muscle contraction, heart rhythm, and pain perception. Abnormalities in their function can lead to various serious diseases such as arrhythmia, epilepsy, hypertension, neuropathic pain, and cancer. Therefore, ion channels are highly valuable drug targets—over 15% of approved drugs target ion channels currently, demonstrating their irreplaceable therapeutic value in cardiovascular, neurological, and analgesic fields.
MCE has collected a library of over 5,000 reported ion channel-related bioactive compounds targeting major sites such as Na+ channels, K+ channels, Ca2+ channels, GABA receptors, iGluRs, and others. Using AI models, these compounds are characterized through both 2D representations (molecular fingerprints, pharmacophores) and 3D representations (3D conformation) to screen for a collection of lead-like compounds highly similar to known active molecules. Additionally, an hERG channel prediction algorithm integrating XGB and ISE mapping strategy is employed to assess and exclude potential cardiotoxicity in the library.. This step significantly reduces safety risks in subsequent screenings, particularly for ion channel drug development related to cardiovascular systems (e.g., Nav1.5, Cav1.2), effectively minimizing failures due to hERG inhibition and serving as a valuable tool for ion channel drug screening.
Cat. No.: HY-D0858DR
CAS No.: 117961-21-4
Synonyms: 2-Morpholinoethanesulphonic acid hemisodium (Standard)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
