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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
mono-ADP-ribosyltransferase
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "mono-ADP-ribosyltransferase" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P80322
Synonyms: SIR2L6, SIRT6, NAD-dependent protein deacylase sirtuin-6, NAD-dependent protein deacetylase sirtuin-6, Protein mono-ADP-ribosyltransferase sirtuin-6, Regulatory protein SIR2 homolog 6, SIR2-like protein 6, hSIRT6
PARP10-IN-2 is a potent mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 3.64 μM for human PARP10. PARP10-IN-2 reveals potent inhibition on PARP2 and PARP15 with IC50s of 27 μM and 11 μM for human PARP2 and human PARP15, respectively .
PARP10-IN-3 is a selective mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 480 nM for human PARP10. PARP10-IN-3 reveals potent inhibition on PARP2 and PARP15 with IC50s of 1.7 μM for human PARP2 and human PARP15, respectively .
Cat. No.: HY-148709
CAS No.: 1708103-76-7
Target:
Research Areas:
ARTD10/PARP10-IN-1 (compound 23) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD7/PARP15, ARTD8/PARP14, ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 (ARTD1/PARP1) with IC50s of 1.7 μM, 1.6 μM, 0.8 μM, and 4.4 μM, respectively .
Cat. No.: HY-176456
CAS No.: 3064731-00-3
Target:
Research Areas:
PARP14 inhibitor 2 (Compound 3) is an orally active and highly selective PARP14 inhibitor with an IC50 value of <30 nM. PARP14 inhibitor 2 inhibits the mono-ADP-ribosyltransferase activity of PARP14 and regulates IFN-γ and IL-4 signaling, reversing protumor macrophage polarization and inhibiting anti-tumor inflammatory responses. PARP14 inhibitor 2 is promising for research of PARP14-related diseases such as tumors, atopic dermatitis and autoimmune diseases .
Cat. No.: HY-148710
CAS No.: 1708103-69-8
Target:
Research Areas:
ARTD10/PARP10-IN-2 (compound 19) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 ARTD1/PARP1 with IC50s of 2.0 μM, and 9.7 μM, respectively .
Cat. No.: HY-P77298
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ART4; Dombrock Blood Group Carrier Molecule Splice Variant III; Prev. DO; NAD(P)(+)--Arginine ADP-ribosyltransferase; ARTC4; mono(ADP-Ribosyl)Transferase 4; DOK1; mono-ADP-ribosyltransferase 4; ADP-ribosyltransferase 4 (Dombrock Blood Group); mono(ADP-Rib
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P77300
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ART4; Dombrock Blood Group Carrier Molecule Splice Variant III; Prev. DO; NAD(P)(+)--Arginine ADP-ribosyltransferase; ARTC4; mono(ADP-Ribosyl)Transferase 4; DOK1; mono-ADP-ribosyltransferase 4; ADP-ribosyltransferase 4 (Dombrock Blood Group); mono(ADP-Rib
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P77301
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ART4; Dombrock Blood Group Carrier Molecule Splice Variant III; Prev. DO; NAD(P)(+)--Arginine ADP-ribosyltransferase; ARTC4; mono(ADP-Ribosyl)Transferase 4; DOK1; mono-ADP-ribosyltransferase 4; ADP-ribosyltransferase 4 (Dombrock Blood Group); mono(ADP-Rib
Species:
Rat
Source:
HEK293
Cat. No.: HY-P77297
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ART4; Dombrock Blood Group Carrier Molecule Splice Variant III; Prev. DO; NAD(P)(+)--Arginine ADP-ribosyltransferase; ARTC4; mono(ADP-Ribosyl)Transferase 4; DOK1; mono-ADP-ribosyltransferase 4; ADP-ribosyltransferase 4 (Dombrock Blood Group); mono(ADP-Rib
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P77299
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ART4; Dombrock Blood Group Carrier Molecule Splice Variant III; Prev. DO; NAD(P)(+)--Arginine ADP-ribosyltransferase; ARTC4; mono(ADP-Ribosyl)Transferase 4; DOK1; mono-ADP-ribosyltransferase 4; ADP-ribosyltransferase 4 (Dombrock Blood Group); mono(ADP-Rib
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P87707
Synonyms: SIR2L6, SIRT6, NAD-dependent protein deacylase sirtuin-6, NAD-dependent protein deacetylase sirtuin-6, Protein mono-ADP-ribosyltransferase sirtuin-6, Regulatory protein SIR2 homolog 6, SIR2-like protein 6, hSIRT6
Cat. No.: HY-P74409
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ART3; Ecto-ADP-ribosyltransferase 3; ADP-ribosyltransferase 3 (Inactive); mono-ADP-ribosyltransferase; ARTC3; NAD(P)(+)--Arginine ADP-ribosyltransferase; ADP-ribosyltransferase C2 And C3 Toxin-Like 3; mono(ADP-Ribosyl)Transferase; NAD(P)(+)--Arginine ADP-
Species:
Human
Source:
HEK293
Cat. No.: HY-P702952
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: SIRT6; HSIRT6; Sirtuin 6; SIR2L6; Protein mono-ADP-ribosyltransferase Sirtuin-6; Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 6 (S. Cerevisiae); NAD-Dependent Protein Deacetylase Sirtuin-6; Sirtuin (Silent Mating Type Information Regulati
Species:
Human
Source:
E. coli
Cat. No.: HY-P703626
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: SIRT6; HSIRT6; Sirtuin 6; SIR2L6; Protein mono-ADP-ribosyltransferase Sirtuin-6; Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 6 (S. Cerevisiae); NAD-Dependent Protein Deacetylase Sirtuin-6; Sirtuin (Silent Mating Type Information Regulati
Species:
Human
Source:
E. coli
Cat. No.: HY-P701951
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PARP14; Protein mono-ADP-ribosyltransferase PARP14; Poly(ADP-Ribose) Polymerase Family Member 14; B Aggressive Lymphoma Protein 2; ARTD8; Poly [ADP-Ribose] Polymerase 14; BAL2; PARP-14; KIAA1268; B-Aggressive Lymphoma 2; PART8; Collaborator Of STAT6; ADP-
Species:
Human
Source:
E. coli
Cat. No.: HY-P701952
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PARP14; Protein mono-ADP-ribosyltransferase PARP14; Poly(ADP-Ribose) Polymerase Family Member 14; B Aggressive Lymphoma Protein 2; ARTD8; Poly [ADP-Ribose] Polymerase 14; BAL2; PARP-14; KIAA1268; B-Aggressive Lymphoma 2; PART8; Collaborator Of STAT6; ADP-
Species:
Human
Source:
E. coli
Cat. No.: HY-P811793
Synonyms: ADPRTL1, KIAA0177, PARPL, PARP4, Protein mono-ADP-ribosyltransferase PARP4, 193 kDa vault protein, ADP-ribosyltransferase diphtheria toxin-like 4, PARP-related/IalphaI-related H5/proline-rich, Poly [ADP-ribose] polymerase 4, Vault poly(ADP-ribose) polymerase, ARTD4, PH5P, PARP-4, VPARP
Cat. No.: HY-P811793A
Synonyms: ADPRTL1, KIAA0177, PARPL, PARP4, Protein mono-ADP-ribosyltransferase PARP4, 193 kDa vault protein, ADP-ribosyltransferase diphtheria toxin-like 4, PARP-related/IalphaI-related H5/proline-rich, Poly [ADP-ribose] polymerase 4, Vault poly(ADP-ribose) polymerase, ARTD4, PH5P, PARP-4, VPARP
Cat. No.: HY-P76734
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ART1; ADP-ribosyltransferase C2 And C3 Toxin-Like 1; ADP-ribosyltransferase 1; mono(ADP-Ribosyl)Transferase 1; ARTC1; ADP-ribosyltransferase 2; CD296; CD296 Antigen; ART2; RT6; GPI-Linked NAD(P)(+)--Arginine ADP-ribosyltransferase 1
Species:
Cynomolgus
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
