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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
oncometabolite
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "oncometabolite" in MCE Product Catalog:
64
63
63 Cited Publications
Synonyms: DL-Lactic acid sodium; E-270 sodium
Target:
Environmental Pollutants Endogenous Metabolite Bacterial Hydroxycarboxylic Acid Receptor (HCAR)
Research Areas:
Lactic acid (DL-Lactic acid) sodium (60% w/w in water) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid sodium (60% w/w in water) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid sodium (60% w/w in water) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity . Lactic acid sodium (60% w/w in water) also has antimicrobial activity, which can be used as a food preservative .
This product has a content (w/w) of 60%, and 1 mL of the system contains 798 mg of Lactic acid sodium, i.e., a concentration of 798 mg/mL (i.e., 7.12 M).
This product has a content (w/w) of 60%, and 1 mL of the system contains 798 mg of Lactic acid sodium, i.e., a concentration of 798 mg/mL (i.e., 7.12 M).
63
63 Cited Publications
Synonyms: DL-Lactic acid potassium; E-270 potassium
Research Areas:
Lactic acid (DL-Lactic acid) potassium is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid potassium is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid potassium is an oncometabolite and has immune protective role of lactate in anti-tumor immunity . Lactic acid also potassium has antimicrobial activity, which can be used as a food preservative .
63
63 Cited Publications
Synonyms: DL-Lactic acid calcium; E-270 calcium
Target:
Environmental Pollutants Endogenous Metabolite Bacterial Hydroxycarboxylic Acid Receptor (HCAR)
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Lactic acid (DL-Lactic acid) calcium is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid calcium is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid calcium is an oncometabolite and has immune protective role of lactate in anti-tumor immunity . Lactic acid calcium also has antimicrobial activity, which can be used as a food preservative .
19
Cat. No.: HY-W015114
CAS No.: 63512-50-5
Synonyms: (S)-2-Hydroxyglutaric acid disodium
Cat. No.: HY-W015883S4
CAS No.: 194160-45-7
Synonyms: (S)-2-Hydroxyglutaric acid
Cat. No.: HY-W015883S
CAS No.: 201595-62-2
Cat. No.: HY-W015883S3
CAS No.: 24461-32-3
Cat. No.: HY-B2227BS
CAS No.: 344299-52-1
Synonyms: DL-Lactic acid-d4 sodium; E-270-d4 sodium
Cat. No.: HY-B2227BS1
CAS No.: 1219802-24-0
Synonyms: DL-Lactic acid-d3 sodium; E-270-d3 sodium
Cat. No.: HY-W015114R
CAS No.: 63512-50-5
Synonyms: (S)-2-Hydroxyglutaric acid disodium (Standard)
Cat. No.: HY-W015883S2
CAS No.: 100858-52-4
Cat. No.: HY-W769991
CAS No.: 1173021-18-5
Synonyms: Lactic acid sodium-13C2
Cat. No.: HY-121916
CAS No.: 1355446-05-7
Target:
Research Areas:
ML309 is a highly selective and potent inhibitor of the R132H mutant isocitrate dehydrogenase 1 (IDH1 R132H), with an IC50 of 96 nM. ML309 is a competitive inhibitor of α-KG, with a Ki value of 156 nM, and its inhibitory activity against the wild-type IDH1 is greater than 35 μM. ML309 effectively reduces the production of the tumor metabolite 2-HG in U87MG cells. ML309 can be used as a chemical probe to study the role of the mutant IDH1 in cancer .
Cat. No.: HY-W744986
Synonyms: (2S)-2-Hydroxyglutaric acid-d5 disodium
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
