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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
p-PI3K
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "p-PI3K" in MCE Product Catalog:
64
64 Publications Verification
Cat. No.: HY-18234A
CAS No.: 103476-89-7
5
1
1 Cited Publications
Cat. No.: HY-N0819
CAS No.: 89412-79-3
Cat. No.: HY-P99422
CAS No.: 2247114-85-6
Synonyms: SHR-1316
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Research Areas:
Cat. No.: HY-18234
CAS No.: 55123-66-5
Cat. No.: HY-18234C
CAS No.: 24125-16-4
Category:
Cat. No.: HY-N3085
CAS No.: 52589-11-4
Category:
Phellodendron amurense Rupr. Flavanonols Flavonoids Rutaceae Metabolic Disease Phenols Polyphenols Plants Disease Research Fields
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Cat. No.: HY-18234B
CAS No.: 24365-47-7
Cat. No.: HY-18234AR
CAS No.: 103476-89-7
Category:
Cat. No.: HY-163511
PI3K/Akt/mTOR-IN-4 (compound 4r) is a potent PI3K/Akt/mTOR and tubulin polymerization inhibitor. PI3K/Akt/mTOR-IN-4 induce apoptosis and cell cycle arrest at G2/M phase. PI3K/Akt/mTOR-IN-4 decreases the expression of p-PI3K, p-Akt, and p-mTOR, β-tubulin .
Cat. No.: HY-149092
CAS No.: 2097497-16-8
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Anticancer agent 109 (compound 6-15) is an inhibitor of the Gas6-Axl axis with anti-cancer activity. Anticancer agent 109 inhibits the expression of Gas6 and Axl, and the expression p-PI3K and p-AKT in cancer cells, leads to G1 phase arrest and promotes cancer cells apoptosis, and inhibits tumor growth significantly in nude mouse tumor bearing models .
Cat. No.: HY-156080
CAS No.: 3052306-60-9
PI3K-IN-48 is a PI3K inhibitor with IC50 value of 1.55 ± 0.18 μM for A549 cells. PI3K-IN-48 can induce G0/G1 phase arrest, cell apoptosis, and down-regulate expression of p-PI3K and p-Akt. PI3K-IN-48 can be used for human lung cancers diseases research .
Cat. No.: HY-N0819R
CAS No.: 89412-79-3
Category:
Cat. No.: HY-183069
FKL-137 is a GLUT1 and PI3K/AKT signaling pathway inhibitor. FKL-137 binds to GLUT1, reduces glucose uptake and lactate secretion, downregulates glucose metabolism-related proteins, and inhibits erythroleukemia cell proliferation. FKL-137 downregulates PI3K, p-PI3K, AKT, p-AKT levels, disrupts the PI3K/AKT-GLUT1 positive feedback loop, and suppresses erythroleukemia cell proliferation. FKL-137 induces apoptosis via upregulated Bax, Cleaved-PARP and downregulated Bcl-2, PARP. FKL-137 can be used for the research of erythroleukemia .
Cat. No.: HY-183478
CAS No.: 39740-82-4
Target:
Ser/Thr Protease Cathepsin Autophagy SARS-CoV Atg8/LC3 NO Synthase COX p62 Arginase PTEN NF-κB PI3K Akt p38 MAPK ERK Reactive Oxygen Species (ROS)
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
