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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
pig skin
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "pig skin" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-W010056
CAS No.: 623-91-6
Target:
1
Sulbentine (Dibenzthione) is a thiadiazine-class antifungal agent. Sulbentine exhibits fungicidal and fungistatic activity against Trichophyton mentagrophytes. Sulbentine can be used for the research of dermatophyte infection .
Cat. No.: HY-N6821
CAS No.: 129499-78-1
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2-O-α-D-Glucopyranosyl-L-ascorbic Acid is an orally active glucoside derivative of ascorbic acid. 2-O-α-D-Glucopyranosyl-L-ascorbic Acid can be hydrolyzed by α-glucosidase to release ascorbic acid. 2-O-α-D-Glucopyranosyl-L-ascorbic Acid inhibits melanin synthesis, prevents UV-induced cell damage, and promotes collagen synthesis in skin fibroblasts. 2-O-α-D-Glucopyranosyl-L-ascorbic Acid also induces oxidative stress to inhibit tumor growth. 2-O-α-D-Glucopyranosyl-L-ascorbic Acid can be used in research related to tumors, inflammation, and other conditions .
Synonyms: N-Stearoyl phytosphingosine
Cat. No.: HY-Y0850U3
CAS No.: 9002-89-5
Synonyms: Polyvinyl alcohol (Mw 125000, 98-99% hydrolyzed, ~2800 polymerization); Poly(Ethenol) (Mw 125000, 98-99% hydrolyzed, ~2800 polymerization)
Cat. No.: HY-W013762
CAS No.: 77-94-1
Research Areas:
Tributyl citrate is a low-toxicity and orally active citrate ester with no genotoxicity or skin sensitizing activity. Tributyl citrate also acts as a plasticizer, solvent, FDA-approved indirect food additive, and topical anesthetic, among other uses. Tributyl citrate induces a needle-prick insensitivity response that lasts for more than 2 hours, and a 5% suspension of it temporarily eliminates the corneal reflex in rabbits. Tributyl citrate causes no significant systemic toxicity in rats and cats at most tested doses, and only may cause growth retardation and gastrointestinal reactions such as diarrhea and nausea at high doses or with repeated oral administration .
Cat. No.: HY-W087907
CAS No.: 530-75-6
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Acetylsalicylsalicylic acid exhibits immunogenicity that induces contact sensitivity and causes skin erythema and slight edema in guinea pigs .
Cat. No.: HY-19443
CAS No.: 299460-62-1
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UCB-35440 is an orally active histamine H1 receptor antagonist and 5-lipoxygenase inhibitor. UCB-35440 can be used for the research of dermatologic inflammatory conditions .
Cat. No.: HY-141582S
CAS No.: 1354806-91-9
Synonyms: N-Stearoyl phytosphingosine-d3
Cat. No.: HY-118834
CAS No.: 70497-14-2
Synonyms: Lyngbyatoxin A
Target:
Cat. No.: HY-164010
CAS No.: 607737-00-8
Research Areas:
SUN-1334H free base is an orally active inhibitor for histamine H1 receptor, with an IC50 of 20.3 nM and Ki of 9.7 nM. SUN-1334H free base inhibits histamine-induced contractions of isolated guinea-pig ileum with an IC50 of 0.198 μM. SUN-1334H free base inhibits histamine-induced bronchoconstriction in guinea pigs, histamine-induced skin wheals in beagle dogs, and ovalbumin-induced rhinitis in guinea pigs .
Cat. No.: HY-117896
CAS No.: 138828-39-4
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SC-50605 and SC-51146 are second-generation leukotriene B4 (LTB4) receptor antagonists that effectively inhibit LTB4-induced chemotaxis in guinea pigs. SC-50605 targets the LTB4 receptor and has the potential to inhibit inflammatory diseases such as asthma, rheumatoid arthritis, and skin diseases. .
Cat. No.: HY-180411
CAS No.: 146461-98-5
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SM-15178 is a potent, orally active and selective leukotriene B4 (LTB4) receptor antagonist with an IC50 of 0.30 μM. SM-15178 attenuates LTB4 (HY-107608)-induced neutrophil accumulation in mouse skin and bronchoconstriction in guinea pigs. SM-15178 emonstrates significant anti-inflammatory efficacy across multiple animal models of inflammation. SM-15178 can be used for the research of chronic inflammatory diseases such as inflammatory bowel disease, psoriasis, and asthma .
Cat. No.: HY-W130596
CAS No.: 122-72-5
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Cat. No.: HY-119958
CAS No.: 74161-27-6
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Acamelin is a Benzofuranoquinone compound that acts as a contact sensitizer. It can be isolated from the heartwood of Acacia melanoxylon R. Br., an Australian blackwood. Acamelin induces positive skin reactions and contact allergy in guinea pigs. It is applicable to research related to allergic contact dermatitis .
Cat. No.: HY-123497
CAS No.: 336884-84-5
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R116031 is a selective Neurokinin-1 (NK-1) receptor antagonist with a Ki of 0.45 nM for human NK-1 receptor. R116031 inhibits Substance P (HY-P0201)-induced peripheral effects (skin reactions and plasma extravasation in guinea pigs) and a central effect (thumping in gerbils).R116031 labeled with 3H significantly accumulate in the striatum, olfactory tubercule, olfactory bulb and locus coeruleus in gerbils models. R116031 can be used as a positron emission tomography (PET) ligand for PET imaging .
Cat. No.: HY-W040536
CAS No.: 6440-58-0
Synonyms: Dimethyloldimethyl hydantoin
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DMDM hydantoin (Dimethyloldimethyl hydantoin) is a hydantoin-derived formaldehyde-releasing preservative and allergen. DMDM hydantoin releases formaldehyde via hydrolysis in water, including under physiological pH conditions, and the release amount is affected by pH, concentration, composition, temperature and storage duration. DMDM hydantoin exerts bactericidal effects by mediating the cross-linking of proteins, RNA and DNA through the released formaldehyde, thereby inhibiting metabolism and cell division. DMDM hydantoin can induce allergic contact dermatitis directly, via the released formaldehyde, or through both pathways simultaneously. DMDM hydantoin is skin-irritating, and the released formaldehyde brings toxicological risks including carcinogenicity, mutagenicity and reproductive toxicity after entering the body. DMDM hydantoin can be used in studies related to allergic contact dermatitis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
